Results 211 to 220 of about 288,320 (254)

Trends in the Prevalence of Macrosomia Among Live Births in Greece: A Nationwide Analysis, 1980-2023. [PDF]

open access: yesCureus
Vlachadis N   +9 more
europepmc   +1 more source

APC

ACM SIGMETRICS Performance Evaluation Review, 2012
Due to the infamous "memory wall" problem and a drastic increase in the number of data intensive applications, memory rather than processor has become the leading performance bottleneck of modern computing systems. Evaluating and understanding memory system performance is increasingly becoming the core of high-end computing. Conventional memory metrics,
Xian-He Sun, Dawei Wang
openaire   +2 more sources

Screening for APC Mutations Based on Detection of Truncated APC Proteins

Digestive Diseases and Sciences, 1998
Mutation of the adenomatous polyposis coli (APC) gene is frequently found in colorectal tumors from both familial adenomatous polyposis (FAP) and non-FAP patients. Analysis of APC mutation is time-consuming and costly due to the large size of the APC gene.
O, Tominaga   +3 more
openaire   +2 more sources

APC: the plot thickens

Current Opinion in Genetics & Development, 1999
Adenomatous polyposis coli (APC) is an important tumour suppressor in the human colon. It is conserved between human and flies, and promotes, together with Axin and glycogen synthase kinase 3 (GSK3), the degradation of the Wnt-signalling effector beta-catenin.
openaire   +2 more sources

APC

2016
Joanna Louise Groden   +2 more
  +4 more sources

APC in Cell Migration

2009
Adenomatous Polyposis Coli (APC) is a tumor suppressor protein involved in the initiation and progression of colon cancer. The most widely accepted function ofAPC is to participate to the Wnt signaling pathway, by downregulating beta-catenin and thereby controlling gene transcription and cell proliferation.
openaire   +2 more sources

The APC-EB1 Interaction

2009
Changes in cell proliferation seen in cancers initiated by adenomatous polyposis coli (APC) gene mutation are driven by the loss of an ability to negatively regulate the canonical WNT signalling pathway. However, mutant APC proteins also lack the ability to interact with a number of other ligands and it is possible that the loss of these interactions ...
openaire   +2 more sources

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