Results 21 to 30 of about 531,671 (288)

Association of CDH1, FANCB and APC Gene Polymorphisms 
with Lung Cancer Susceptibility in Chinese Population

Chinese Journal of Lung Cancer, 2022
Background and objective Lung cancer is the main cause of cancer-related death globally. Single nucleotide polymorphism (SNP) is one of the important factors leading to the occurrence of lung cancer, but its mechanism has not been elucidated.
Lianchun SU, Hua HUANG, Min GAO, Yongwen LI, Ruifeng SHI, Chen CHEN, Xuanguang LI, Guangsheng ZHU, Hongyu LIU, Jun CHEN   +9 more
doaj   +1 more source

Coste de la publicación en abierto de artículos de autoría española en cinco áreas de las ciencias sociales

Arbor: Ciencia, Pensamiento y Cultura, 2021
La publicación en abierto de los artículos conlleva unos gastos conocidos como cargos por procesamiento de artículos (APC, en sus siglas en inglés). El objetivo de este trabajo es determinar el coste de los artículos publicados en abierto mediante APC de
Antonia Ferrer-Sapena, Christian Vidal-Cabo, Rafael Aleixandre-Benavent, Juan Carlos Valderrama-Zurián   +3 more
doaj   +1 more source

Evaluation of the burden of HPV-related hospitalizations as a useful tool to increase awareness: 2007–2017 data from the sicilian hospital discharge records [PDF]

, 2020
In light of the implementation of human papillomavirus (HPV) prevention strategies, epidemiological studies in different geographical areas are required in order to assess the impact of HPV-related diseases.
Amato L., Amodio E., Candiloro S., Casuccio A., Costantino C., Maranto M., Marrella A., Palmeri S., Pizzo S., Restivo V., Vitale F.   +10 more
core   +1 more source

APC Communiqué [PDF]

, 2012
This is the archive of the fall 2012 APC communiqué, a bi-annual newsletter, which has a special report on Ambassador Zhong Jianhua's visit entitled "China’s Africa Envoy discusses China-Africa ...
Boston University African Presidential Center
core   +6 more sources

Wnt/beta-catenin/Tcf signaling: A critical pathway in gastrointestinal tumorigenesis [PDF]

, 2002
Cancers of the gastrointestinal tract, including the liver, bile ducts, and pancreas, constitute the largest group of malignant tumors. Colorectal cancer is one of the most common neoplastic diseases in Western countries and one of the leading causes of ...
Bommer, G., Göke, B., Kolligs, F. T.
core   +2 more sources

Cell-type specific MyD88 signaling is required for intestinal tumor initiation and progression to malignancy

OncoImmunology, 2018
The signal adapter MyD88, an essential component of Toll-like receptor (TLR) signaling, is important for gut-microbiome interactions. However, its contribution to cancer and its cell-type specific functions are controversially discussed.
Anne Holtorf, Anja Conrad, Bernhard Holzmann, Klaus-Peter Janssen   +3 more
doaj   +1 more source

Cross-sectional observational study protocol: missing microbes in infants born by caesarean section (MiMIC): antenatal antibiotics and mode of delivery

BMJ Open, 2022
Introduction The intestinal microbiome in early life plays a major role in infant health and development. Factors like antibiotic exposure, breast/formula feeding and mode of delivery are known to affect the microbiome.
Eugene M Dempsey, Catherine Stanton, R Paul Ross, C Anthony Ryan, Elaine Patterson, John F Cryan, Alicja K Warda, Sofia D Forssten, Mairead N O'Riordan, Carol-Anne O’Shea, Finola Keohane, Grainne Meehan, Orlagh O’Connor   +12 more
doaj   +1 more source

Arabidopsis ULTRAVIOLET-B-INSENSITIVE4 maintains cell division activity by temporal inhibition of the anaphase-promoting complex/cyclosome [PDF]

, 2011
The anaphase-promoting complex/cyclosome (APC/C) is a multisubunit ubiquitin ligase that regulates progression through the cell cycle by marking key cell division proteins for destruction.
Berckmans, Barbara, Boudolf, Véronique, De Jaeger, Geert, De Veylder, Lieven, De Wit, Kevin, Heyman, Jefri, Koncz, Csaba, Lessa Alvim Kamei, Claire, Van Den Daele, Hilde, Verkest, Aurine   +9 more
core   +2 more sources

APC-β-catenin-TCF signaling silences the intestinal guanylin-GUCY2C tumor suppressor axis. [PDF]

, 2020
Sporadic colorectal cancer initiates with mutations in APC or its degradation target β-catenin, producing TCF-dependent nuclear transcription driving tumorigenesis. The intestinal epithelial receptor, GUCY2C, with its canonical paracrine hormone guanylin,
Bashir, Babar, Blomain, Erik S, Caparosa, Ellen, Pattison, Amanda M, Rappaport, Jeffrey A, Snook, Adam E, Stem, Jonathan, Waldman, Scott A   +7 more
core   +1 more source

Another 'futile quest'? A simulation study of Yang and Land's Hierarchical Age-Period-Cohort model [PDF]

, 2013
Background: Whilst some argue that a solution to the age-period-cohort (APC) 'identification problem' is impossible, numerous methodological solutions have been proposed, including Yang and Land's Hierarchical-APC (HAPC) model: a multilevel model ...
Bell, Andrew, Jones, Kelvyn
core   +5 more sources