Results 21 to 30 of about 290,331 (256)

Cell-type specific MyD88 signaling is required for intestinal tumor initiation and progression to malignancy

OncoImmunology, 2018
The signal adapter MyD88, an essential component of Toll-like receptor (TLR) signaling, is important for gut-microbiome interactions. However, its contribution to cancer and its cell-type specific functions are controversially discussed.
Anne Holtorf, Anja Conrad, Bernhard Holzmann, Klaus-Peter Janssen   +3 more
doaj   +1 more source

Association of CDH1, FANCB and APC Gene Polymorphisms 
with Lung Cancer Susceptibility in Chinese Population

Chinese Journal of Lung Cancer, 2022
Background and objective Lung cancer is the main cause of cancer-related death globally. Single nucleotide polymorphism (SNP) is one of the important factors leading to the occurrence of lung cancer, but its mechanism has not been elucidated.
Lianchun SU, Hua HUANG, Min GAO, Yongwen LI, Ruifeng SHI, Chen CHEN, Xuanguang LI, Guangsheng ZHU, Hongyu LIU, Jun CHEN   +9 more
doaj   +1 more source

Coste de la publicación en abierto de artículos de autoría española en cinco áreas de las ciencias sociales

Arbor: Ciencia, Pensamiento y Cultura, 2021
La publicación en abierto de los artículos conlleva unos gastos conocidos como cargos por procesamiento de artículos (APC, en sus siglas en inglés). El objetivo de este trabajo es determinar el coste de los artículos publicados en abierto mediante APC de
Antonia Ferrer-Sapena, Christian Vidal-Cabo, Rafael Aleixandre-Benavent, Juan Carlos Valderrama-Zurián   +3 more
doaj   +1 more source

Comparative analysis of global and Chinese trends in the burden of ischemic stroke attributable to secondhand smoke from 1990–2021

Tobacco Induced Diseases
Introduction Ischemic stroke (IS) represents a major health burden in China, and tobacco control is recognized as a practical and effective strategy to alleviate this impact. This study examines the influence of secondhand smoke (SHS) on the IS burden in
Xiao Zhou, Jiaming Liu, Xin Li
doaj   +1 more source

The ABCs of APCs

Nursing Management (Springhouse), 2000
To make sure your ED has money to spend, you need an Ambulatory Payment Classifications process that's streamlined, error-free, and compliant with regulations. Here's how.
openaire   +3 more sources

Research on Control Strategy of Auxiliary Power Converter in Dual-Current Train AC/DC Conversion

Chengshi guidao jiaotong yanjiu
[Objective] The start-stop control strategy for the auxiliary power converter (APC) under AC/DC conversion conditions of dual-current trains, and for train HAVC(heating, ventilation and air conditioning) system are studied, aiming to avoid APC ...
YANG Zhihao, ZHANG Yuguang, LU Jinxiao
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Cross-sectional observational study protocol: missing microbes in infants born by caesarean section (MiMIC): antenatal antibiotics and mode of delivery

BMJ Open, 2022
Introduction The intestinal microbiome in early life plays a major role in infant health and development. Factors like antibiotic exposure, breast/formula feeding and mode of delivery are known to affect the microbiome.
Eugene M Dempsey, Catherine Stanton, R Paul Ross, C Anthony Ryan, Elaine Patterson, John F Cryan, Alicja K Warda, Sofia D Forssten, Mairead N O'Riordan, Carol-Anne O’Shea, Finola Keohane, Grainne Meehan, Orlagh O’Connor   +12 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Impact and underlying mechanisms of osteoblast-derived exosomes on biological characteristics of prostate cancer cells

陆军军医大学学报
Objective To investigate the effects and potential mechanisms of osteoblast-derived exosomes on the biological properties of prostate cancer (PC) cells.
LI Jingyi, CHEN Jiajiu, LI Yaoming
doaj   +1 more source