Results 51 to 60 of about 531,671 (288)
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Modulation of the gut microbiome with nisin
Scientific Reports, 2023 Nisin is a broad spectrum bacteriocin used extensively as a food preservative that was identified in Lactococcus lactis nearly a century ago. We show that orally-ingested nisin survives transit through the porcine gastrointestinal tract intact (as ...
Catherine O’Reilly +12 more
doaj +1 more source
Immunogenicity of targeted lentivectors [PDF]
, 2014 To increase the safety and possibly efficacy of HIV-1 derived lentivectors (LVs) as an anti-cancer vaccine, we recently developed the Nanobody (Nb) display technology to target LVs to antigen presenting cells (APCs).
Adotévi +67 more
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FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Tobacco Induced DiseasesIntroduction Smoking is a major risk factor for laryngeal cancer (LC). Understanding the impact of smoking on the changing disease burden of LC is crucial for LC prevention in China and provides a scientific basis for formulating targeted LC prevention ...
Xue Gu +7 more
doaj +1 more source
Hematology, Transfusion and Cell Therapy, 2023 Objetivos: Abastecer os hospitais é responsabilidade dos bancos de sangue e o primeiro passo para conseguir hemocomponentes seguros para transfusão, é uma somatória de medidas como a realização da triagem sorológica nas amostras dos doadores sangue ...
JAD Santos +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
Вавиловский журнал генетики и селекции, 2015 Six regulatory SNPs (single nucleotide polymorphisms) of two human APC and MLH1 genes (rs75996864, rs76241113, rs78037487, rs80112297, rs80313086 and rs1800734) were evaluated by the previously developed rSNP_Guide method to compute the significance of ...
D. A. Rasskazov +9 more
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Giant rectal fecaloma treated with carbonated soft drink and argon plasma coagulation
European Journal of Case Reports in Internal MedicineConstipation is a common gastrointestinal disorder affecting approximately 15% of the population, with a higher prevalence in women and older adults. It can be classified as primary, including functional constipation, pelvic floor dysfunction, and slow ...
Philippe Attieh +3 more
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Cancer Management and Research, 2021 Shaohua Guo,1,2,* Yumeng Ye,3,* Xinyi Liu,4 Yuan Gong,5 Mingyan Xu,4 Lele Song,4,6 Hongyi Liu1 1Department of General Surgery, The First Medical Center of the Chinese PLA General Hospital, Beijing, People’s Republic of China; 2Department of ...
Guo S +6 more
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