Results 41 to 50 of about 12,228 (219)
Hearing Thresholds and Serum Apelin Levels in Patients with Vertebrobasilar Insufficiency [PDF]
, 2014 Objective: Vertebrobasilar insufficiency (VBI) is a clinical entity that results from the decrease in flow volumes due to hemodynamic changes in the vertebral artery and its branches.
Selda Demirtaş +5 more
core +1 more source
, 2022 The forest plots of pooled estimates of standardized mean differences of circulating apelin (A), apelin/HDL-c (B), apelin/LDL-c (C), apelin/triglycerides (D), and apelin/total cholesterol (E) levels between cases with CVDs and controls.
Saeed Hosseini (13184173) +8 more
core +1 more source
Inhibition of the apelin/apelin receptor axis decreases cholangiocarcinoma growth [PDF]
Cancer Letters, 2017 Cholangiocarcinoma (CCA) is a malignancy of the biliary epithelium that is associated with low five-year survival. The apelin receptor (APLNR), which is activated by the apelin peptide, has not been studied in CCA. The purpose of this study is to determine if inhibition of the apelin/APLNR axis can inhibit CCA growth.Immunohistochemistry, rtPCR ...
Hall, C +12 more
openaire +3 more sources
Plasma apelin: A novel biomarker for predicting diabetes
, 2017 Background: Apelin regulates insulin sensitivity and secretion in animals. However, whether plasma apelin predicts incident diabetes in humans remains unknown. Methods: We studied a cohort including 447 subjects (148 men, 299 women) without diabetes and
洪啟盛;林茂欣;高憲立;莊立民;李弘元;林昭維 +1 more
core +1 more source
Early vessel destabilization mediated by Angiopoietin-2 and subsequent vessel maturation via Angiopoietin-1 induce functional neovasculature after ischemia. [PDF]
, 2013 We assessed whether Angiopoietin-2 (Ang2), a Tie2 ligand and partial antagonist of Angiopoietin-1 (Ang1), is required for early vessel destabilization during postischemic angiogenesis, when combined with vascular growth factors.
Di Qin (107446) +20 more
core +2 more sources
Apelin Serum Level in Egyptian Patients with Chronic Hepatitis C
Mediators of Inflammation, 2011 Objective. Highlighting the apelin system would present a new therapeutic target for liver disease. Apelin; endogenous ligand for the orphan receptor APJ, was recently suggested to be associated with fibrosis progression and cirrhosis in addition to ...
Hala O. El-Mesallamy +3 more
doaj +1 more source
Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia
Advanced Science, EarlyView.The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian +12 more
wiley +1 more source
, 2021 BACKGROUND & AIMS: Apelin is the endogenous ligand of its G-protein coupled receptor, APJ, and apelin serum levels are increased in human liver diseases.
Francis, Heather +30 more
core +1 more source
Apelin receptor in GtoPdb v.2023.1 [PDF]
, 2023 The apelin receptor (nomenclature as agreed by the NC-IUPHAR Subcommittee on the apelin receptor [73] and subsequently updated [75]) responds to apelin, a 36 amino-acid peptide derived initially from bovine stomach.
Williams, Thomas L. +9 more
core +1 more source
Frontiers in Pharmacology, 2020 Apelin is the endogenous ligand for APJ, a G-protein-coupled receptor. Apelin gene and protein are widely distributed in the central nervous system and peripheral tissues. The role of apelin in chronic inflammatory pain is still unclear.
Shuangyu Lv +5 more
doaj +1 more source