Results 71 to 80 of about 23,711 (313)
Frontiers in Physiology, 2021 The apelin receptor (APJ) is a member of the family A of G-protein-coupled receptors (GPCRs) and is involved in range of physiological and pathological functions, including fluid homeostasis, anxiety, and depression, as well as cardiovascular and ...
Gong Hu +4 more
semanticscholar +1 more source
Apelin decreases myocardial injury and improves right ventricular function in monocrotaline-induced pulmonary hypertension [PDF]
, 2009 Falcao-Pires I, Goncalves N, Henriques-Coelho T, Moreira-Goncalves D, Roncon-Albuquerque R Jr, Leite-Moreira AF. Apelin decreases myocardial injury and improves right ventricular function in monocrotaline-induced pulmonary hypertension.
Falcão-Pires I +5 more
core +1 more source
Journal of Men's HealthThis study was aimed to investigate the effects of acute and chronic High Intensity Interval Training (HIIT) on Irisin, BDNF (brain-derived neurotrophic factor), and Apelin levels. The study included twenty-one male soccer referees.
semanticscholar +1 more source
Effects of adenotonsillectomy on plasma inflammatory biomarkers in obese children with obstructive sleep apnea: A community-based study. [PDF]
, 2015 BackgroundObesity and obstructive sleep apnea syndrome (OSA) are highly prevalent and frequently overlapping conditions in children that lead to systemic inflammation, the latter being implicated in the various end-organ morbidities associated with these
Alonso-Álvarez, ML +7 more
core +1 more source
On the cardiovascular activity of apelin [PDF]
Cardiovascular Research, 2005 See article by Ashley et al. [8] (pages 73–82) in this issue. Apelin, a peptide recently isolated from bovine stomach extracts, has been seen to act as an endogenous ligand of the orphan G-protein-coupled APJ receptor [1]. The structure of apelin preproteins was deduced from the sequences of the relevant cDNAs.
openaire +4 more sources
Frontiers in Pharmacology, 2020 Apelin is the endogenous ligand for APJ, a G-protein-coupled receptor. Apelin gene and protein are widely distributed in the central nervous system and peripheral tissues. The role of apelin in chronic inflammatory pain is still unclear.
Shuangyu Lv +5 more
doaj +1 more source
, 2016 Angiogenesis involves the formation of new blood vessels by sprouting or splitting of existing blood vessels. During sprouting, a highly motile type of endothelial cell, called the tip cell, migrates from the blood vessels followed by stalk cells, an ...
Dallinga, Marchien G. +5 more
core +3 more sources
G-Protein coupled receptor signalling in pluripotent stem cell-derived cardiovascular cells: Implications for disease modelling [PDF]
, 2015 Human pluripotent stem cell derivatives show promise as an in vitro platform to study a range of human cardiovascular diseases. A better understanding of the biology of stem cells and their cardiovascular derivatives will help to understand the strengths
Dolatshad, NF +4 more
core +1 more source
Requirement of Apelin-Apelin Receptor System for Oxidative Stress-Linked Atherosclerosis [PDF]
The American Journal of Pathology, 2007 The recently identified endogenous peptide apelin and its specific apelin receptor (APJ) are currently being considered as potential regulators in vascular tissue. Previously, we reported apelin mediates phosphorylation of myosin light chain and elicits vasoconstriction in vascular smooth muscle.
Minoru Kihara +14 more
openaire +2 more sources
British Journal of Clinical Pharmacology, 2022 Chronic kidney disease (CKD) is common and cardiovascular disease (CVD) is its commonest complication. The apelin system is a potential therapeutic target for CVD but data relating to apelin in CKD are limited. We examined expression of the apelin system
Duuamene Nyimanu +8 more
semanticscholar +1 more source