Results 21 to 30 of about 28,192 (282)
Rhomboid-like proteins in Apicomplexa: phylogeny and nomenclature
Rhomboids form a family of polytopic intramembrane serine proteases. In Toxoplasma gondii, an essential activity called microneme protein protease 1 (MPP1) cleaves secreted adhesive proteins within their transmembrane domains, at a site conserved in similar proteins of other Apicomplexa.
Dominique Soldati+2 more
openaire +7 more sources
Background Cryptosporidium spp. are globally distributed parasites that infect epithelial cells in the microvillus border of the gastrointestinal tract of all classes of vertebrates.
L. Tumova+12 more
semanticscholar +1 more source
Chromatin dynamics can regulate all DNA-dependent processes. Access to DNA within chromatin is orchestrated mainly by histones and their posttranslational modifications (PTMs).
Vanessa Severo+6 more
doaj +1 more source
Spatial distribution and evaluation of risk factors for bovine neosporosis in Rondônia, Brazil [PDF]
Neospora caninum is an important worldwide parasite responsible for causing abortion in animals. Due to limited information on the occurrence of infection by this parasite in the state of Rondônia, Brazil, this study aimed to determine the seroprevalence
A.M. Andrade Júnior+14 more
doaj +1 more source
Currently, the drugs used for toxoplasmosis have severe toxicity to human cells, and the treatment still lacks effective and safer alternatives. The search for novel drug targets is timely.
Mariana Galvão Ferrarini+12 more
doaj +1 more source
Conoid extrusion regulates glideosome assembly to control motility and invasion in Apicomplexa
Members of Apicomplexa are defined by apical cytoskeletal structures and secretory organelles, tailored for motility, invasion and egress. Gliding is powered by actomyosin-dependent rearward translocation of apically secreted transmembrane adhesins.
Nicolas Dos Santos Pacheco+7 more
semanticscholar +1 more source
Cystoisospora belli is an intestinal Apicomplexan parasite associated with diarrheal illness and disseminated infections in humans, mainly immunocompromised individuals such as those living with the human immunodeficiency virus (HIV) or acquired ...
Ana Luz Galván-Díaz+5 more
doaj +1 more source
How Apicomplexa Parasites Secrete and Build Their Invasion Machinery.
Apicomplexa are obligatory intracellular parasites that sense and actively invade host cells. Invasion is a conserved process that relies on the timely and spatially controlled exocytosis of unique specialized secretory organelles termed micronemes and ...
M. Cova, M. Lamarque, M. Lebrun
semanticscholar +1 more source
Paving the Way: Contributions of Big Data to Apicomplexan and Kinetoplastid Research
In the age of big data an important question is how to ensure we make the most out of the resources we generate. In this review, we discuss the major methods used in Apicomplexan and Kinetoplastid research to produce big datasets and advance our ...
Robyn S. Kent+7 more
doaj +1 more source
A survey on Apicomplexa protozoa in sheep slaughtered for human consumption
Infections with the Apicomplexa Toxoplasma gondii, Neospora caninum, and Sarcocystis spp. are common causes of reproductive disorders in sheep. However, few epidemiological studies regarding co-infections with these three protozoa are reported in sheep ...
G. Dessì+9 more
semanticscholar +1 more source