Results 91 to 100 of about 39,255 (266)
Advances in Unconventional and Sustainable Synthetic Approaches to Benzopyran Scaffolds
The Chemical Record, EarlyView.This review provides a comprehensive and critical analysis of low‐impact synthetic methodologies reported in the last 8 years (2018–2026) for the construction of benzopyran‐derived scaffolds, such as coumarins, flavones, chromones, chromenes, and chromanes. The benzopyran scaffold is a versatile family of heterocycles found in a wide range of bioactive
Nathalia B. Sá +4 more
wiley +1 more source
Journal of Current Oncology and Medical Sciences, 2023 Apigenin is a member of the flavonoid family that has been used in medicine for a long time. Apigenin is one of the compounds that has been used for a long time to treat various disorders and diseases.
Roshanak Ale-Esmaiel +1 more
doaj
Interaction of apigenin with calf thymus (CT) DNA.
, 2014 (A) UV-Vis spectra of CT-DNA, apigenin and apigenin+CT-DNA. (B) UV-Vis spectra of CT-DNA with varying concentration of apigenin ranging from 0.025 mM to 0.2 mM in solution.
Rajnee Kanwal (533137) +3 more
core +1 more source
Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges
British Journal of Pharmacology, EarlyView.This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu +6 more
wiley +1 more source
Apigenin decreases expression of the myofibroblast phenotype
FEBS Letters, 2001 We investigated the effect of the dietary flavonoid apigenin on myofibroblast function. We report that in myofibroblasts treated with apigenin, proliferation and basal levels of α1(I) collagen and α‐smooth muscle actin mRNAs were markedly reduced. Apigenin also attenuated the transforming growth factor‐β‐stimulated increases of α1(I) collagen and α ...
Ricupero, Dennis A +4 more
openaire +2 more sources
Bioavailability of Apigenin from Apiin-Rich Parsley in Humans
, 2006 Aim: Absorption and excretion of apigenin after the ingestion of apiin-rich food, i.e. parsley, was tested. Methods: Eleven healthy subjects (5 women, 6 men) in the age range of 23–41 years and with an average body mass index of 23.9 ± 4.1 kg/m2 took ...
Meyer, Hellen;Bolarinwa, Adrian;Wolfram, Guenther;Linseisen, Jakob
core +1 more source
Coloration Technology, EarlyView.Abstract This study investigates a sustainable dyeing and finishing strategy for recycled nylon 6,6 and organic cotton fabrics dyed with weld. Following meta‐mordant dyeing using alum under Natural Organic Dye Standard (NODS)‐compliant conditions, the fabrics were subjected to functional finishing with titanium dioxide as a multifunctional ...
Recep Karadag +2 more
wiley +1 more source
Apigenin as a Multi-Targeted Agent in Gastrointestinal Cancers: A Systems Pharmacology Approach [PDF]
Advanced Pharmaceutical BulletinIntroduction: Apigenin, a dietary flavonoid found in various medicinal plants, has demonstrated notable anticancer effects. However, its multi-targeted molecular mechanisms in gastrointestinal (GI) cancers remain poorly understood.
Duaa Kamel Al-Moussawi +4 more
doaj +1 more source
Immunology, EarlyView.Unlike generalized mTOR inhibitors, Torin‐1 uniquely drives compensatory upregulation of TIM‐3 on human NK cells, shielding them from immunosuppression while concurrently inhibiting glioblastoma (GBM) growth. Selecting or preconditioning ex vivo NK cell products for high TIM‐3 expression can offer a combination strategy for adoptive cell therapy in GBM.
Yuning Liu +11 more
wiley +1 more source
Scientific ReportsBronchiectasis is a complex, heterogeneous inflammatory chronic respiratory disease with an unknown etiology. In the context of increasingly severe drug resistance, there is an urgent need to explore new treatment strategies.
Haizhu Huang +14 more
doaj +1 more source