Results 71 to 80 of about 39,255 (266)
Apigenin: A Promising Molecule for Cancer Prevention [PDF]
Pharmaceutical Research, 2010 Apigenin, a naturally occurring plant flavone, abundantly present in common fruits and vegetables, is recognized as a bioactive flavonoid shown to possess anti-inflammatory, antioxidant and anticancer properties. Epidemiologic studies suggest that a diet rich in flavones is related to a decreased risk of certain cancers, particularly cancers of the ...
Sanjeev, Shukla, Sanjay, Gupta
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Apigenin induces cell cycle arrest at the G2/M phase.
, 2013 HT-29 cells were treated with the indicated concentrations of apigenin. (A) Relative viability of cells treated with apigenin for 72 hr was measured using the Cell Counting Kit-8.
Tomoyuki Taniguchi (337403) +5 more
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Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events
Phytotherapy Research, EarlyView.An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia +1 more
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Phytotherapy Research, EarlyView.Graphical representation of ethnomedical uses, major bioactive compounds, pharmacological potential and toxicological risks of Ruta graveolens L. ABSTRACT Ruta graveolens L. is widely used in traditional European, Asian, African, and South American medicine for digestive, nervous, cardiovascular, respiratory, and reproductive disorders.
Tetiana Serhiienko +3 more
wiley +1 more source
Journal of Chemical Research, 2012 An efficient method for the synthesis of apigenin (4’,5,7-trihydroxyflavone, a traditional medicine) from phloroglucinol and anisaldehyde has been developed. This transformation features a green method for hydroxyl protection as methyl ethers and a different way for cyclisation using iodine in DMSO. The overall yield of 40% is satisfactory.
Jin Wang +7 more
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, 2012 Programmed death ligand 1 (PD-L1) is a T cell inhibitory molecule expressed by activated T cells and antigen presenting cells, as well as by various tumor types. PD-L1 expression is believed to contribute to immune evasion by breast cancer cells.
Hickey, Megan
core
Apigenin Protects Hypertensive Intracerebral Hemorrhage by Regulating Trx1 Through Binding to PRDX2
Phytotherapy Research, EarlyView.ABSTRACT Intracerebral hemorrhage (ICH) remains the most severe stroke subtype with high mortality and disability rates. Although apigenin has shown cerebroprotective potential in preclinical studies, its mechanism of action, particularly in hypertensive ICH, remains poorly understood.
Hao‐chen Xu +6 more
wiley +1 more source
The flavonoid apigenin upregulates CD26/DPPIV on human colorectal carcinoma cells
, 2013 CD26/dipeptidyl peptidase IV is a cell-surface glycoprotein expressed by various cell types, including epithelial cells of the normal human colon. CD26 levels increase during epithelial cell differentiation but become dysregulated during malignancies ...
Lefort, Emilie
core
, 2016 Physicochemical investigation of the red alga Acanthophora spicifera (Vahl) Borgesen, collected from Al-Shoaiba coast, Red Sea, Saudi Arabia, led to the isolation of a flavone from the algal tissue with acetone.
Essam A. Salem +3 more
core +1 more source
Plant‐Derived Natural Product Nanodelivery System in Cancer Therapy
Phytotherapy Research, EarlyView.This review comprehensively summarizes the recent progress and emerging concepts in nanotechnology‐based delivery systems for plant‐derived natural products, with a particular focus on their application in precision cancer therapy. ABSTRACT Plant‐derived natural products have emerged as important sources of anticancer agents because of their diverse ...
Changqi Shi +9 more
wiley +1 more source