Results 101 to 110 of about 9,527 (222)

Stage‐Specific Metabolic and Proteomic Dynamics Underlying Ripening and Quality Formation in Tropical Evergreen Pomegranate

eFood, Volume 7, Issue 4, August 2026.
Integrated multi‐omics reveals that pomegranate ripening between 90 and 130 days drives optimal sugar‐acid balance and pigmentation via coordinated regulation of phenylpropanoid, flavonoid, and carbohydrate metabolism pathways. ABSTRACT Pomegranate fruit development involves coordinated physiological, metabolic, and proteomic changes shaping coloration
Yawen Zhang, Ling Wei, Kaibing Zhou, Qin Deng, Muhammad Mobeen Tahir, Hongxia Wu, Minjie Qian   +6 more
wiley   +1 more source

Antioxidant activity and molecular mechanisms of typical flavonoids in Dendrobium officinale

Shipin yu jixie
ObjectiveTo explore the antioxidant activity and molecular mechanism of the typical flavonoid apigenin and its glycoside compounds in Dendrobium officinale.MethodsThe antioxidant activities of apigenin and its glycoside compounds were assessed using the ...
WANG Yixue, QIN Si, ZHOU Runze, LYU Chenghao   +3 more
doaj   +1 more source

Therapeutic Potential of Berberis vulgaris in Modulating Metabolic Syndrome Biomarkers: Mechanistic Insights and Functional Food Implications

Food Frontiers, Volume 7, Issue 4, July 2026.
ABSTRACT Barberry (Berberis vulgaris) has emerged as a promising functional food candidate for the management of metabolic syndrome due to its diverse bioactive constituents, particularly berberine. This review synthesizes current experimental and clinical evidence regarding its effects on glycemic control, lipid metabolism, blood pressure regulation ...
Fakhar Shahid, Ifrah Jabeen, Muhammad Inam‐ur‐Raheem, Amin Mousavi Khaneghah, Muhammad Abid, Rana Muhammad Aadil   +5 more
wiley   +1 more source

Exploring the molecular mechanism of apigenin in treating bronchiectasis based on network pharmacology and molecular docking

Scientific Reports
Bronchiectasis is a complex, heterogeneous inflammatory chronic respiratory disease with an unknown etiology. In the context of increasingly severe drug resistance, there is an urgent need to explore new treatment strategies.
Haizhu Huang, Jiahui Han, Yanping Liu, Qinzhe Zhang, Yue Zhou, Shaochu Zheng, Chuanlin Zhou, Chongxi Bao, Cao Qing, Wei Lu, Xiaopu Wu, Yun Jiang, Liangming Zhang, Jing Luo, Jinliang Kong   +14 more
doaj   +1 more source

Anti-inflammation Activity Evaluation of Apigenin-O-Glycosides and Apigenin-C-Glycosides

Shipin gongye ke-ji, 2022
Objective: The anti-inflammatory activities of apigenin-7-O-β-D-glucopyranoside, apigenin 5-O-glucoside, vitexin and isovitexin were evaluated. Methods: Changes of protein in THP-1 cells pretreated with flavonoids were measured by Western blot test.
Hui LI, Siyi PAN, Xiaoyun XU
openaire   +1 more source

In vitro anti-inflammatory effect of apigenin in the Helicobacter pylori-infected gastric adenocarcinoma cells

, 2014
AP-1, activator protein 1; CagA, cytotoxin associated antigen; COX-2, cyclooxygenase-2; ERK1/2, extracellular signal regulated kinase 1/2; EtBr, ethidium bromide; H2DCF-DA, dihydrodichlorofluorescein diacetate; HE, dihydroethidium; ICAM-1, intercellular ...
Yuan-Chuen Wang, Kai-Ming Huang
core   +1 more source

Pyruvate Kinase M2 Mediates Apigenin‐Induced Energy Crisis and Apoptosis in Colon Cancer Cells

Food Frontiers, Volume 7, Issue 4, July 2026.
Apigenin, a dietary flavonoid with low toxicity, induces profound bioenergetic collapse in colon cancer cells by downregulating PKM2. This metabolic crisis, characterized by suppressed glycolysis and mitochondrial dysfunction, ultimately triggers robust apoptosis.
Ke Zhang, Xingtao Zhou, Xujie Wang, Mingyong Xie   +3 more
wiley   +1 more source

Mechanistic insights into EIF6 as a target of Apigenin in alleviating chondrocyte senescence

Experimental Gerontology
Purpose: Apigenin, a flavonoid found in edible plants, has demonstrated therapeutic potential in various diseases, but its role in knee osteoarthritis (KOA) remains unclear. This study aimed to identify the potential targets and mechanisms of Apigenin in
Erliang Li, Hui Yu, Xin Xu, Min Wang, Mingyi Yang, Zhi Yang, Peng Xu   +6 more
doaj   +1 more source

Apigenin induces cell cycle arrest at the G2/M phase.

, 2013
HT-29 cells were treated with the indicated concentrations of apigenin. (A) Relative viability of cells treated with apigenin for 72 hr was measured using the Cell Counting Kit-8.
Tomoyuki Taniguchi (337403), Yoshihiro Sowa (451995), Toshiyuki Sakai (309632), Yosuke Iizumi (337402), Masakatsu Oishi (337401), Wakana Goi (337404)   +5 more
core   +1 more source

Multi‐Induction Strategies in Crops: Mechanisms, Synergistic Effects, and Sustainable Applications for Enhanced Secondary Metabolite Production

Food Frontiers, Volume 7, Issue 4, July 2026.
This review analyzes single/combined abiotic (light, water, nutrients, hormones) and biotic (microbes, yeast) elicitors regulating signaling, gene expression, and metabolism to boost plant secondary metabolites. It highlights synergistic multielicitor strategies for crop quality and functional foods, while critically addressing current limitations and ...
Yifei Sun, Daoyan Xiao, Xingyue Li, Zhaofei Wang, Maoqin Xia, Chao Song, Hong‐Lei Li   +6 more
wiley   +1 more source