Results 121 to 130 of about 51,943 (224)

Apigenin inhibits renal cell carcinoma cell proliferation

Oncotarget, 2017
Apigenin, a natural flavonoid found in vegetables and fruits, has antitumor activity in several cancer types. The present study evaluated the effects and mechanism of action of apigenin in renal cell carcinoma (RCC) cells. We found that apigenin suppressed ACHN, 786-0, and Caki-1 RCC cell proliferation in a dose- and time-dependent manner.
Meng, Shuai, Zhu, Yi, Li, Jiang-Feng, Wang, Xiao, Liang, Zhen, Li, Shi-Qi, Xu, Xin, Chen, Hong, Liu, Ben, Zheng, Xiang-Yi, Xie, Li-Ping   +10 more
openaire   +3 more sources

In Vitro Antimicrobial Activity and In Vivo Intestinal Barrier Regulation by Commiphora leptophloeos Bark Extract in 5‐Fluorouracil–Induced Mucositis

Chemistry &Biodiversity, Volume 23, Issue 4, April 2026.
ABSTRACT This study evaluated the phytochemical composition, antimicrobial activity, and in vivo protective effects of the hydroethanolic extract from Commiphora leptophloeos stem bark (HECL) against 5‐fluorouracil (5‐FU)‐induced intestinal mucositis. Despite the extensive traditional use of C.
Stphannie Jamyla de Araújo Barbosa, Renato Dantas‐Medeiros, Susana Barbosa Ribeiro, Amanda Silveira da Silva, Lucas Vinicius Souza de Carvalho, Rafaela Torres Dantas da Silva, Gerlane Coelho Bernardo Guerra, Raimundo Fernandes de Araújo Júnior, Nizyara Costa da Silva, Raphael Victor Silva Andrade, Gabrielle Marques de Paiva, Silvana Maria Zucolotto, Rafaela Alcindo Silva de Sousa Fé, Maria Laura de Souza Lima, Raphaël Grougnet, Sergio Ortiz, Ana Caroline Zanatta, Aurigena Antunes de Araújo   +17 more
wiley   +1 more source

Apigenin protects ischemic stroke by regulating intestinal microbiota homeostasis, regulates brain metabolic profile

Frontiers in Pharmacology
Background and ObjectiveIschemic stroke is a cerebrovascular disease with highly incidence. Previous research has demonstrated that apigenin provides protective effects against ischemic stroke.
Jinjian Li, Qiaoli Xu, Xiaoming Xu, Wei He, Hui Zhang, Hui Zhang, Haoxu Ren, Haoxu Ren, Yue Wang, Xu Wang, Xu Wang, Dexi Zhao, Dexi Zhao   +12 more
doaj   +1 more source

A 2,3-diphenylpyrido[1,2-a] pyrimidin-4-one derivative inhibits specific angiogenic factors induced by TNF-α

Saudi Pharmaceutical Journal, 2019
Low-grade chronic inflammation is a key process of angiogenesis in tumour progression. We investigated whether a synthetic analogue of apigenin, the 2-(3,4-dimethoxyphenyl)-3-phenyl-4H-pyrido[1,2-a] pyrimidin-4-one (called DB103), interfered with the ...
Serena Del Turco, Luca Quattrini, Rocchina Colucci, Melania Gaggini, Concettina La Motta, Giuseppina Basta   +5 more
doaj   +1 more source

Valorization of Banana Biomass: Nutritional and Phytochemical Insights With Applications in Food and Allied Industries

eFood, Volume 7, Issue 2, April 2026.
Composition, biological activity and food application of banana biomass. ABSTRACT The global banana processing industry generates substantial organic waste in the form of peels, leaves, stems, and flowers, posing both environmental challenges and opportunities for valorization within a circular economy framework.
Bushra Iram Fatima, Saeed Akhtar, Muhammad Zulqarnain Khan, Muhammad Qamar, Tariq Ismail, Wisha Saeed, Elham Assadpour, Tuba Esatbeyoglu, Seid Mahdi Jafari   +8 more
wiley   +1 more source

Potential Hypoglycemic, Hypolipidemic, and Hypouricemic Bioactive Components From Ampelopsis grossedentata Explored by Affinity Ultrafiltration With Three Enzyme Targets

eFood, Volume 7, Issue 2, April 2026.
By integrating bioaffinity ultrafiltration coupled with HPLC‐MS/MS, this study identified quercetin, myricetrin, dihydromyricetin, and taxifolin from Ampelopsis grossedentata as key inhibitors of α‐glucosidase, pancreatic lipase, and xanthine oxidase, highlighting the promising potential of A.
Siyang Mao, Chu Chu, Yanzhi Xiong, Mengjia Xu, Jian Yang, Mingquan Guo   +5 more
wiley   +1 more source

Study on the encapsulation mechanism of collagen hydrogel for apigenin

Journal of Future Foods
Poor stability and low solubility of flavonoids extremely limited their efficient application in functional foods. Hydrogel delivery systems have good stabilizing and enhancing effects on flavonoids.
Wenya Meng, Yuru Wu, Qian Zhou, Jing Li, Xu Liu, Kang Liu   +5 more
doaj   +1 more source

Effects of Juice Processing on Anti-inflammatory Flavonoids in Plant Foods [PDF]

, 2009
Apigenin glycosides are abundant in parsley, celery, and chamomile tea and possess unique anti-inflammatory properties in vitro. Apigenin O-glycosides have been evaluated in foods by hydrolysis and comparison to aglycone standards, but intact O- and C ...
Hostetler, Greg
core  

Traditional Chinese Herbal Plant Penthorum chinense Pursh: Health Factors and Its Future Development

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
This review expounds on the species, morphological characteristics, and distribution areas of Penthorum chinense Pursh, summarizes the active ingredients mainly including flavonoids in PCP and their extraction methods. It also pays particular attention to the pharmacological effects of PCP, such as liver protection, antioxidation, anti‐inflammation ...
Hui Zhang, Ning Zhang, Baoguo Sun
wiley   +1 more source

Protective Mechanism of Aqueous Extract From Ixeris sonchifolia in Myocardial Ischemia–Reperfusion Injury: Insights From Network Pharmacology and Experimental Validation

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
This study evaluated KDZ aqueous extract's therapeutic potential for MI/RI and investigated its mechanism. In a mouse MI/RI model, the aqueous extract mitigated injury and preserved cardiac function. Liquid chromatography‐mass spectrometry (LC–MS) identified eighty‐six components. Based on Compound‐target‐disease interaction network and KEGG enrichment
Xiaoxia Tian, Baoyi Chen, Longtai Chen, Kuan Liu, Jiazhao Chu, Fang Liu, Sijing Feng, Lina Lai   +7 more
wiley   +1 more source