Results 181 to 190 of about 9,527 (222)

Apigenin as an anticancer agent

Phytotherapy Research, 2020
AbstractApigenin is an edible plant‐derived flavonoid that has been reported as an anticancer agent in several experimental and biological studies. It exhibits cell growth arrest and apoptosis in different types of tumors such as breast, lung, liver, skin, blood, colon, prostate, pancreatic, cervical, oral, and stomach, by modulating several signaling ...
Muhammad Imran, Tanweer Aslam Gondal, Muhammad Atif   +2 more
exaly   +4 more sources

Apigenin and apigenin-derivatives from artichokes: urine excretion in humans

, 2011
Apigenin and apigenin glycosides are the main flavonoids in artichokes. Thus, their 24 h-urinary excretion was investigated, as a marker of absorption, in six women after consumption of two steamed artichokes. No enzymes treatment was performed and the urine metabolites were investigated by HPLC-MS/MS.
RICIPUTI, YLENIA, T. P. Dew, CABONI, MARIA, G. Williamson   +3 more
openaire   +3 more sources

Labeling of apigenin with 131I and bioactivity of 131I-apigenin in male and female rats

Journal of Radioanalytical and Nuclear Chemistry, 2009
Apigenin (4′,5,7-trihydroxyflavone), one of the most common flavonoids, has been shown to possess a variety of biological activities including tumor growth inhibition and chemopreventation. In the present study, apigenin was labeled with 131I using iodogen method and investigated of its bioactivity.
Seyitoglu B., Yurt Lambrecht F., Durkan K.   +2 more
openaire   +3 more sources

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Evaluation of Properties of Apigenin and [G-3H]Apigenin and Analytic Method Development

Journal of Pharmaceutical Sciences, 1997
This study provides baseline data and analytical methods to assist in the evaluation of apigenin, a plant flavonoid with promising chemopreventive activity against skin cancer. Apigenin was freely soluble in dimethylsulfoxide (> 100 mg/mL), but it had low solubility (0.00135-1.63 mg/mL) in all the other solvents and surfactants tested, especially in ...
B, Li, D H, Robinson, D F, Birt
openaire   +2 more sources

On the Accumulation of Apigenin in Chamomile Flowers

Planta Medica, 1990
By preparing and analysing extracts of fresh chamomile flowers from outdoor and greenhouse cultures, it was possible to show that apigenin does not actually occur in living chamomile flowers. Apigenin is the result of post-harvest processes converting apigenin 7-glycoside and its derivatives into the aglycone.
A, Schreiber, R, Carle, E, Reinhard
openaire   +2 more sources

UHPLC assisted simultaneous separation of apigenin and prednisolone and its application in the pharmacokinetics of apigenin

Journal of Chromatography B, 2019
A new ultra-high performance liquid chromatography-mass spectrometry-mass spectrometry (UHPLC-MS/MS) system has been formulated for the resolution of closely related drugs apigenin (API, a bioflavinoid) and prednisolone (PRD) from their mixture. This developed method comprised of a "BEH™ C18 column (50 mm × 2.1 mm, 1.7 μm)" using acetonitrile and 0.1 ...
Ehab M, Elzayat, Faiyaz, Shakeel, Sultan, Alshehri, Mohamed A, Ibrahim, Mohammad A, Altamimi, Mohsin, Kazi, Fars Kaed, Alanazi, Nazrul, Haq   +7 more
openaire   +2 more sources

The Anticancer Potential of Apigenin Via Immunoregulation

Current Pharmaceutical Design, 2021
Apigenin is an edible flavonoid widely distributed in natural plants, including most vegetables and fruits. Previous studies have revealed that apigenin possesses multiple biological functions by demonstrating antiinflammatory, anti-oxidative, anti-bacterial, anti-viral, anti-tumor and cardiovascular protective effects.
Lu Xu, Mohamed Y. Zaky, Waleed Yousuf, Anwar Ullah, Gehad R. Abdelbaset, Yingqiu Zhang, Osama M. Ahmed, Shuyan Liu, Han Liu   +8 more
openaire   +2 more sources

Apigenin

Apigenin, a flavonoid naturally found in many vegetables, fruits, and medicinal plants, possesses strong antioxidant properties. Apigenin is produced in plants through flavonoid biosynthesis, starting with phenylalanine. Thanks to its three hydroxyl groups, it reduces cellular damage by scavenging free radicals.
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Development of apigenin monoclonal antibodies and an immunoassay for the quantification of apigenin in celery

Food Chemistry
Apigenin, a 4',5,7-trihydroxyflavone compound with diverse biological activities, is found abundantly in vegetables and fruits, particularly in celery. The identification and quantification of apigenin have become critical indicators for quality control in raw pharmaceuticals, finished drugs, and formulations.
Di, Sun, Chunlei, Cao, Feng, Sun, Yifan, Liu, Zihui, Jin, Qiyang, Zhao, Yue, He, Yaohai, Zhang, Yongliang, Cui   +8 more
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The synthesis and bioactivity of apigenin derivatives

Fitoterapia
Apigenin, a naturally occurring compound with a flavone core structure, is known for its diverse bioactivities, including anti-inflammation, anti-toxicant, anti-cancer and so on. There has been significant interest in the medicinal chemistry community.
Shun, Liu, Xing, Zheng, Zhongqin, Luo, Caihong, Tang, Yufei, Hu, Qingying, Peng, Pengbing, Mi, Hongfei, Chen, Xu, Yao   +8 more
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