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Effect of Apigenin on Neurodegenerative Diseases

CNS & Neurological Disorders - Drug Targets
Abstract: Neurodegenerative diseases (NDDs), such as Alzheimer's and Parkinson's, are the most frequent age-related illnesses affecting millions worldwide. No effective medication for NDDs is known to date and current disease management approaches include neuroprotection strategies with the hope of maintaining and improving the function of neurons ...
Kajal Gaur, Yasir Hasan Siddique
openaire   +2 more sources

Oxidative coupling of apigenin

Tetrahedron, 1970
Abstract Two novel biflavonyls have been prepared by phenolic oxidative coupling of apigenin, using alkaline potassium ferricyanide as the oxidizing agent. The structures of these dimers have been established as 3,3- and 3,3′-biapigeninyl respectively, primarily by spectroscopic methods.
R.J. Molyneux, A.C. Waiss, W.F. Haddon
openaire   +1 more source

Chemoprevention by Apigenin

2017
Phytoestrogens are compounds derived from plants with steroid-like structures. They are also called as plant hormones and bind to estrogen receptor (ER). The five main classes of phytoestrogens include flavones, isoflavones, lignans, coumestans, and stilbenes.
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Behavioral characterisation of the flavonoids apigenin and chrysin

Fitoterapia, 2000
The behavioral effects of acute administration of two flavonoids, apigenin and chrysin, contained in Matricaria chamomilla and in Passiflora incarnata, respectively, were studied in rats. The data demonstrate that in our experimental conditions, the two flavonoids were equally able to reduce locomotor activity when injected in rats at a minimal ...
ZANOLI, Paola   +2 more
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Apigenin and Metabolic Effects

2023
Flavonoids, an important plant ingredient, have been known for more than a century and are among the compounds of interest in many clinical experimental studies. Flavonoids are classified into six subclasses. Apigenin belongs to the class of flavones among these subclasses.
TIRAŞ, Sena   +2 more
openaire   +1 more source

Apigenin and inflammation in the brain: can apigenin inhibit neuroinflammation in preclinical models?

Inflammopharmacology
Apigenin is a flavone-kind of flavonoid present in fruits and vegetables. Apigenin exhibits biological activities including neuropharmacological effects against different neurological disorders. In this study, we summarize and discuss the molecular mechanisms of the anti-neuroinflammatory effects of apigenin in neurological disorders.
Tosin A. Olasehinde, Oyinlola O. Olaokun
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Apigenin in Apigenin Nanoliposomes: Development and Validation of an Analytical Technique Based on HPTLC

Research Journal of Biotechnology
Apigenin is a flavonoid found in various fruits and vegetables, aimed at its extensive array of biological actions such as anti-oxidant, anti-viral, antibacterial, anti-inflammatory, including chemo preventive property. Therefore, this study aimed to develop, describe and evaluate apigenin nanoliposomes.
P.P. Shetti, S. Gudasi, M. Kubade
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Apigenin

Skin & Allergy News, 2008
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Effects of Apigenin on the Apoptosis Index of Atherosclerosis

Journal of Cardiovascular Pharmacology
Abstract: Recently, apigenin has been widely studied for its antiatherosclerosis properties, but its mechanism remains to be further elucidated. This study aims to evaluate the expression of LOX-1, Bcl-2, and Bax in apigenin-treated atherosclerotic rats and to explore whether apigenin affect the expression of apoptotic genes.
Zhuo-Nan Jia   +10 more
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Apigenin

2021
openaire   +1 more source

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