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Prediction of the therapeutic mechanism of Sugemule-4 in insomnia treatment using network pharmacology and molecular docking. [PDF]
Medicine (Baltimore)Su R, Wang J, Su D, Su R, Sa C, Bao L.
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Apigenin as an anticancer agent
Phytotherapy Research, 2020AbstractApigenin is an edible plant‐derived flavonoid that has been reported as an anticancer agent in several experimental and biological studies. It exhibits cell growth arrest and apoptosis in different types of tumors such as breast, lung, liver, skin, blood, colon, prostate, pancreatic, cervical, oral, and stomach, by modulating several signaling ...
Muhammad Imran +8 more
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Apigenin-Induced Suicidal Erythrocyte Death
Journal of Agricultural and Food Chemistry, 2011Apigenin, a flavone in fruits and vegetables, stimulates apoptosis and thus counteracts cancerogenesis. Erythrocytes may similarly undergo suicidal cell death or eryptosis, characterized by cell shrinkage and phosphatidylserine exposure at the cell surface.
Zbidah, Mohanad +6 more
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Evaluation of Properties of Apigenin and [G-3H]Apigenin and Analytic Method Development
Journal of Pharmaceutical Sciences, 1997This study provides baseline data and analytical methods to assist in the evaluation of apigenin, a plant flavonoid with promising chemopreventive activity against skin cancer. Apigenin was freely soluble in dimethylsulfoxide (> 100 mg/mL), but it had low solubility (0.00135-1.63 mg/mL) in all the other solvents and surfactants tested, especially in ...
B, Li, D H, Robinson, D F, Birt
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Apigenin and apigenin-derivatives from artichokes: urine excretion in humans
2011Apigenin and apigenin glycosides are the main flavonoids in artichokes. Thus, their 24 h-urinary excretion was investigated, as a marker of absorption, in six women after consumption of two steamed artichokes. No enzymes treatment was performed and the urine metabolites were investigated by HPLC-MS/MS.
RICIPUTI, YLENIA +3 more
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Oxidative coupling of apigenin
Tetrahedron, 1970Abstract Two novel biflavonyls have been prepared by phenolic oxidative coupling of apigenin, using alkaline potassium ferricyanide as the oxidizing agent. The structures of these dimers have been established as 3,3- and 3,3′-biapigeninyl respectively, primarily by spectroscopic methods.
R.J. Molyneux, A.C. Waiss, W.F. Haddon
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The Anticancer Potential of Apigenin Via Immunoregulation
Current Pharmaceutical Design, 2021Apigenin is an edible flavonoid widely distributed in natural plants, including most vegetables and fruits. Previous studies have revealed that apigenin possesses multiple biological functions by demonstrating antiinflammatory, anti-oxidative, anti-bacterial, anti-viral, anti-tumor and cardiovascular protective effects.
Lu Xu +8 more
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