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Protective effects of apigenin, apigenin-8-sulfonate, and apigenin-3′, 8-disulfonate on d-galactosamine-induced acute liver damage in mice

Medicinal Chemistry Research, 2020
The water-soluble sulfated derivatives, apigenin-8-sulfonate sodium (AS) and apigenin-3′, 8-disulfonate sodium (ADS) derived from parent apigenin (AP), were synthesized and characterized by infrared (IR) spectra, hydrogen nuclear magnetic resonance (1H NMR), carbon nuclear magnetic resonance (13C NMR), high-resolution mass spectra (HRMS), and elemental
Xin-Bin Yang, Yu Huang
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Apigenin alleviates STZ-induced diabetic cardiomyopathy

Molecular and Cellular Biochemistry, 2017
Apigenin is an important component of fruits and vegetables in human daily diets. Several cellular and animal models have been performed to demonstrate its anti-oxidant and anti-inflammatory bioactivities. However, the cardioprotective effects of apigenin in diabetic cardiomyopathy (DCM) remain unclear.
Huang-Jun, Liu   +9 more
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Chemoprevention by Apigenin

2017
Phytoestrogens are compounds derived from plants with steroid-like structures. They are also called as plant hormones and bind to estrogen receptor (ER). The five main classes of phytoestrogens include flavones, isoflavones, lignans, coumestans, and stilbenes.
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Effect of Apigenin on Neurodegenerative Diseases

CNS & Neurological Disorders - Drug Targets
Abstract: Neurodegenerative diseases (NDDs), such as Alzheimer's and Parkinson's, are the most frequent age-related illnesses affecting millions worldwide. No effective medication for NDDs is known to date and current disease management approaches include neuroprotection strategies with the hope of maintaining and improving the function of neurons ...
Kajal Gaur, Yasir Hasan Siddique
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Apigenin and inflammation in the brain: can apigenin inhibit neuroinflammation in preclinical models?

Inflammopharmacology
Apigenin is a flavone-kind of flavonoid present in fruits and vegetables. Apigenin exhibits biological activities including neuropharmacological effects against different neurological disorders. In this study, we summarize and discuss the molecular mechanisms of the anti-neuroinflammatory effects of apigenin in neurological disorders.
Tosin A. Olasehinde, Oyinlola O. Olaokun
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Apigenin

Skin & Allergy News, 2008
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The synthesis and bioactivity of apigenin derivatives

Fitoterapia
Apigenin, a naturally occurring compound with a flavone core structure, is known for its diverse bioactivities, including anti-inflammation, anti-toxicant, anti-cancer and so on. There has been significant interest in the medicinal chemistry community.
Shun, Liu   +8 more
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Apigenin

2021
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Zweite synthese des Apigenins

Berichte der deutschen chemischen Gesellschaft, 1905
Marie Breger, St. V. Kostanecki
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Apigenin: Chemistry and Pharmacology

2023
Ana Clara Aprotosoaie, Anca Miron
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