Results 131 to 140 of about 8,460 (160)

APOBEC3B protein expression associates with poor prognosis for breast cancer patients with ER-positive disease. [PDF]

Breast Cancer Res
Schreurs MAC, Timmermans AM, Carpenter MA, Smid M, den Bakker MA, van Deurzen CHM, Harris RS, Martens JWM.   +7 more
europepmc   +1 more source

Impact of mRNA and protein isoforms in lipoprotein metabolism and how to modulate them. [PDF]

Curr Opin Lipidol
Martinovich KM, Cale JM, Aung-Htut MT.
europepmc   +1 more source

APOBEC3 promotes squamous differentiation via IL-1A/AP-1 signaling. [PDF]

Nat Commun
Sturdivant MS, Truong AS, Zhou M, Toomer ED, Beckabir W, Raupp J, Manocha U, Zambrano IA, Tan HJ, Bjurlin MA, Smith AB, Rose TL, Milowsky MI, Wobker SE, Gessner KH, Damrauer JS, Kim WY.   +16 more
europepmc   +1 more source

Multi-omics analysis of the effects of pla2g4a on the prognosis of various cancers and its experimental validation in breast cancer cell lines. [PDF]

Discov Oncol
Qian Y, Yuan Q, Yu H, Ye R, Niu M, Liu F.   +5 more
europepmc   +1 more source

Whole genome sequencing revealed esophageal squamous cell carcinoma related biomarkers. [PDF]

PLoS One
Li M, Li L, Wang X, Zhao Y, Du P, Wang W, Wang Z, Wang Y, Sheng Y, Gu M, Jia X.   +10 more
europepmc   +1 more source

Acquired High Tumor Mutational Burden and Activity of Immunotherapy after Targeted Therapy in Microsatellite Stable Colorectal Cancer. [PDF]

Clin Cancer Res
Yeh C, Artz O, Zhang H, Karnoub ER, Ntiamoah P, Weipert C, Walch H, Harrold E, Keane F, Chalasani S, Segal NH, Foote MB, Cercek A, Pagano A, Maron SB, Diaz LA, Iacobuzio-Donahue CA, Shia J, Rousseau B, Yaeger R.   +19 more
europepmc   +1 more source

An in vitro cytidine deaminase assay to monitor APOBEC activity on DNA. [PDF]

Methods Enzymol
Sanchez A, Buisson R.
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APOBEC-Induced Mutagenesis in Cancer

Annual Review of Genetics, 2022
The initiation, progression, and relapse of cancers often result from mutations occurring within somatic cells. Consequently, processes that elevate mutation rates accelerate carcinogenesis and hinder the development of long-lasting therapeutics. Recent sequencing of human cancer genomes has identified patterns of mutations, termed mutation signatures,
Tony M, Mertz, Christopher D, Collins, Madeline, Dennis, Margo, Coxon, Steven A, Roberts   +4 more
openaire   +2 more sources