Results 91 to 100 of about 5,264 (176)

Suppression of APOBEC3-mediated restriction of HIV-1 by Vif

open access: yesFrontiers in Microbiology, 2014
The APOBEC3 restriction factors are a family of deoxycytidine deaminases that are able to suppress replication of viruses with a single-stranded DNA intermediate by inducing mutagenesis and functional inactivation of the virus.
Yuqing eFeng   +3 more
doaj   +1 more source

87. APOBEC3G and Immunity to Retroviruses

open access: yesMolecular Therapy, 2004
APOBEC3G is capable of providing a cellular defense against retroviruses by deaminating deoxycytidine to deoxyuridine in the first strand of nascent retroviral cDNA. However, this defense can be counteracted by the HIV virion-infectivity factor (Vif), which targets APOBEC3G for degradation by the proteasome.
openaire   +1 more source

Molecular mechanism for regulating APOBEC3G DNA editing function by the non-catalytic domain

open access: yesNature Communications
APOBEC3G, part of the AID/APOBEC cytidine deaminase family, is crucial for antiviral immunity. It has two zinc-coordinated cytidine-deaminase domains.
Hanjing Yang   +6 more
doaj   +1 more source

Prevalence of HBsAg among Moroccan HIV-1 infected patients and APOBEC3G variant frequencies in HIV-1/HBV co-infection

open access: yesJournal of Infection in Developing Countries
Introduction: Human immunodeficiency virus (HIV) / hepatitis B virus (HBV) causes higher rates of liver disease compared to infection with just one virus.
Imane Belbacha   +7 more
doaj   +1 more source

APOBEC3G-vermittelte Hemmung der Masernvirus-Replikation

open access: yes, 2011
Measles virus (MV) is a negative-strand RNA virus which belongs to the family Para-myxoviridae and remains one of the leading causes of morbidity and mortality in the develop-ing world. Following entry of MV into the body, infection of CD150-positive B- and T-cells as well as dendritic cells and monocytes/macrophages leads to a systemic infection ...
openaire   +1 more source

Genetic Diversity of Vif and Vpr Accessory Proteins in HIV-1 Group M Clades. [PDF]

open access: yesViruses
Galzitskaya O   +7 more
europepmc   +1 more source

APOBEC3G

open access: yesSeibutsu Butsuri, 2015
openaire   +2 more sources

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