Results 231 to 240 of about 176,190 (308)
Liver-metabolic stress, apolipoprotein E ε4, and cognition and amyloid burden: findings from the dementia platform Korea trial-ready registry. [PDF]
Ahn YH +8 more
europepmc +1 more source
Identification of rare variants in Alzheimer\u27s disease [PDF]
Cruchaga, Carlos +2 more
core +1 more source
Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI
Abstract Human cerebrovasculature is finely tuned to enable local changes in blood flow to meet the brain's demands, whilst protecting the brain from systemic changes in blood pressure, both acutely during a heartbeat and chronically over time. This review summarises cerebrovascular structure and function, their role in disease and neurodegeneration ...
Ian D. Driver, Kevin Murphy
wiley +1 more source
Slc7a11-Mediated Cystine/Glutamate Antiport Reprograms Macrophage Polarization and Ameliorates Atherosclerosis. [PDF]
Zhou S +12 more
europepmc +1 more source
Abstract IgA nephropathy (IgAN) is a common type of primary glomerulonephritis in children. The pathogenesis of childhood IgAN remains unclear, and there is a lack of effective non‐invasive biomarkers for this disease. Single‐cell RNA sequencing was performed in children with IgAN to delineate cellular and molecular compositions, and subcluster ...
Ling Yu +7 more
wiley +1 more source
Meta-analysis reveals apolipoprotein ε4 confers higher susceptibility to Parkinson's disease dementia in Asian populations. [PDF]
Akhter N +5 more
europepmc +1 more source
Abstract Klotho, a pleiotropic protein initially identified for its role in kidney function, has garnered significant attention for its neuroprotective properties in various neurodegenerative diseases. It regulates key processes, such as oxidative stress, neuroinflammation, synaptic plasticity and myelination, all crucial for maintaining neuronal ...
Amir Arsalan Ghahari +7 more
wiley +1 more source
Blood PCSK9 Impacts Alzheimer's Disease Risk in an <i>APOE</i> Genotype-Dependent Manner: A Prospective Cohort Study. [PDF]
Tao Q +10 more
europepmc +1 more source

