Independent associations of TOMM40 and APOE variants with body mass index [PDF]
, 2019 The TOMM40-APOE variants are known for their strong, antagonistic associations with Alzheimer's disease and body weight. While a stronger role of the APOE than TOMM40 variants in Alzheimer's disease was suggested, comparative contribution of the TOMM40 ...
Arbeev, Konstantin G +10 more
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Pharmacogenomics and Personalized Medicine, 2022 Zhifu Xiao,1,* Haixia Zhao2,* 1Department of Thyroid Surgery, Shanxi Provincial People’s Hospital, Taiyuan, Shanxi, 030012, People’s Republic of China; 2Central Lab, General Hospital of Taiyuan Iron and Steel Group, Taiyuan, Shanxi, 030003 ...
Xiao Z, Zhao H
doaj
Атеросклероз, 2018 Aim: to form a panel of genetic markers for analyzing the risk of long-term adverse prognosis of cardiovascular diseases in Russia population. Material and methods.
E. V. Shakhtshneider +7 more
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The Suggestive Effect of Apo A, Apo B, and Apo A/Apo B on Erectile Dysfunction [PDF]
The Journal of Sexual Medicine, 2021 ABSTRACTBackgroundErectile dysfunction (ED) is closely related to coronary heart disease (CHD). Apolipoprotein (Apo) A1, Apo B, and Apo A/Apo B are known to be predictive factors for CHD. They are not yet a definite laboratory marker for the diagnosis of ED in cardiology. Therefore, we investigated the association between Apo A1, Apo B, and Apo A/Apo B,
Xiucheng, Li, Dongjie, Li
openaire +2 more sources
Crossroads between peripheral atherosclerosis, western-type diet and skeletal muscle pathophysiology: emphasis on apolipoprotein E deficiency and peripheral arterial disease [PDF]
, 2017 Atherosclerosis is a chronic inflammatory process that, in the presence of hyperlipidaemia, promotes the formation of atheromatous plaques in large vessels of the cardiovascular system.
Matsakas, Antonios, Sfyri, Peggy
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RNA-Seq Mouse Brain Regions Expression Data Analysis: Focus on ApoE Functional Network
Journal of Integrative Bioinformatics, 2017 ApoE expression status was proved to be a highly specific marker of energy metabolism rate in the brain. Along with its neighbor, Translocase of Outer Mitochondrial Membrane 40 kDa (TOMM40) which is involved in mitochondrial metabolism, the corresponding
Babenko Vladimir N. +2 more
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Microbiota and Alzheimer's disease: Toward new clinical approaches [PDF]
Medicinski PodmladakAlzheimer’s disease (AD) is now viewed as a systemic disorder in which genetics, the gut microbiome and immune dysregulation converge to accelerate amyloid-β (Aβ) and tau pathology. Genetic studies have identified 70 risk loci. The strongest AD risk loci
Đokić Jelena, Dinić Miroslav
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Artery tertiary lymphoid organs control multi-layered territorialized atherosclerosis B cell responses in aged ApoE-/- mice [PDF]
, 2016 Objective: Explore aorta B cell immunity in aged ApoE-/- mice. Approach and Results: Transcript maps, FACS, immunofluorescence analyses, cell transfers, and Ig-ELISPOT assays showed multi-layered atherosclerosis B cell responses in artery tertiary ...
Andreas J.R. Habenicht +13 more
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The role of the KIBRA and APOE genes in developing spatial abilities in humans
Вавиловский журнал генетики и селекции, 2022 In the contemporary high-tech society, spatial abilities predict individual life and professional success, especially in the STEM (Science, Technology, Engineering, and Mathematics) disciplines.
A. V. Kazantseva +8 more
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Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism [PDF]
, 2018 Table S1. Demographic and clinical features of human subjects used in this study. Figure S1. Aβ deposition in microvessels in AD patients and APPSw/0 mice. Figure S2. Biochemical analysis of Aβ42 aggregates. Figure S3.
Herz, Joachim +9 more
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