Results 1 to 10 of about 2,377,565 (362)
On the Aggregation of Apolipoprotein A-I. [PDF]
Int J Mol Sci, 2022 In vivo, apolipoprotein A-I (ApoA-I) is commonly found together with lipids in so-called lipoprotein particles. The protein has also been associated with several diseases—such as atherosclerosis and amyloidosis—where insoluble aggregates containing ApoA-I are deposited in various organs or arteries.
Frankel R, Sparr E, Linse S.
europepmc +3 more sources
Apolipoprotein A-I and Cancer [PDF]
Frontiers in Pharmacology, 2015 High-density lipoprotein (HDL) and apolipoprotein A-I (apoA-I), the predominant protein in plasma HDL, have long been the focus of intense studies in the field of atherosclerosis and cardiovascular disease.
M. Zamanian-Daryoush, J. DiDonato
semanticscholar +3 more sources
Definitions, 2020 Description Apolipoprotein A-I is the major apoprotein of HDL and is a relatively abundant plasma protein with a concentration of 1.0-1.5 mg/ml. It is a single polypeptide chain with 243 amino acid residues of known primary amino acid sequence. ApoA-I is
S. Hamdan, Apolipoprotein A-I
semanticscholar +4 more sources
The Egyptian Heart Journal, 2020 Background The apolipoprotein B/apolipoprotein A-I ratio was shown to be strongly related to the risk of myocardial infarction in several large-scale studies.
Haitham Galal +2 more
doaj +2 more sources
The apolipoprotein B and apolipoprotein A-I Ratio serves as a strong prognostic factor for the overall survival of patients with colorectal cancer [PDF]
Frontiers in Oncology, 2023 BackgroundThe lipid metabolism status of patients with colorectal cancer (CRC) has not been understood comprehensively. The present study investigated the characteristics of lipid metabolism parameters in CRC patients with or without metastases and ...
Yangxun Pan +18 more
doaj +2 more sources
Apolipoprotein A‐I: the dual face of a protein [PDF]
FEBS Letters, 2016 Conformational plasticity and flexibility are key structural features of ApoAI in lipid metabolism. Amyloidogenic single point mutations, associated with incurable familial amyloidosis with fibril deposition in peripheral organs, may have a dramatic ...
Angela Arciello, R. Piccoli, D. Monti
semanticscholar +5 more sources
Anti-inflammatory mechanism of Apolipoprotein A-I. [PDF]
Front ImmunolApolipoprotein A-I(ApoA-I) is a member of blood apolipoproteins, it is the main component of High density lipoprotein(HDL). ApoA-I undergoes a series of complex processes from its generation to its composition as spherical HDL. It not only has a cholesterol reversal transport function, but also has a function in modulating the inflammatory response ...
Tao X, Tao R, Wang K, Wu L.
europepmc +4 more sources
The Apolipoprotein B/Apolipoprotein A-I Ratio as a Potential Marker of Plasma Atherogenicity [PDF]
Disease Markers, 2015 Background. The apolipoprotein (apo) B/apoA-I ratio represents the balance between apoB-rich atherogenic particles and apoA-I-rich antiatherogenic particles, and this ratio is considered to be a marker of cardiovascular risk.
A. M. Kaneva +3 more
semanticscholar +5 more sources
A comparison of two methods to investigate the metabolism of human apolipoproteins A-I and and A-II.
Journal of Lipid Research, 1978 Two methods are compared for measuring the kinetic parameters of apolipoprotein A-I and A-II metabolism in human plasma. In the first, high density lipoprotein apoproteins were radioiodinated in situ in the lipoprotein particle (endogenous apoprotein ...
J Shepherd +3 more
doaj +2 more sources
Apolipoprotein A-I: Potential Protection Against Intestinal Injury Induced by Dietary Lipid [PDF]
Journal of Inflammation ResearchJue-Xin Wang,1– 3,* Shi-Jia Yu,4,* Gang Huang,1,2 Yan-Bo Yu,1,2 Yan-Qing Li1,2 1Department of Gastroenterology, Qilu Hospital of Shandong University, Jinan, Shandong Province, 250012, People’s Republic of China; 2Laboratory of Translational ...
Wang JX, Yu SJ, Huang G, Yu YB, Li YQ
doaj +2 more sources