Results 1 to 10 of about 178,943 (330)

Lipid‐Free Apolipoprotein A‐I Reduces Progression of Atherosclerosis by Mobilizing Microdomain Cholesterol and Attenuating the Number of CD131 Expressing Cells: Monitoring Cholesterol Homeostasis Using the Cellular Ester to Total Cholesterol Ratio [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundAtherosclerosis is a chronic inflammatory disorder whose development is inversely correlated with high‐density lipoprotein concentration. Current therapies involve pharmaceuticals that significantly elevate plasma high‐density lipoprotein ...
Sushma Kaul, Hao Xu, Manal Zabalawi, Elisa Maruko, Brian E. Fulp, Theresa Bluemn, Kristina L. Brzoza‐Lewis, Mark Gerelus, Ranjuna Weerasekera, Rachel Kallinger, Roland James, Yi (Sherry) Zhang, Michael J. Thomas, Mary G. Sorci‐Thomas   +13 more
doaj   +2 more sources

Impact of Glucose Metabolism Status on the Association between Apolipoprotein A-I and Ischemic Risk in Patients with Coronary Artery Disease: A Large-Sample Cohort Study [PDF]

Endocrinology and Metabolism
Background Apolipoprotein A-I (ApoA-I) is a key cardioprotective lipoprotein. Nevertheless, it remains unclear how ApoA-I relates to ischemic risk across glucose metabolism statuses in patients with coronary artery disease (CAD).
Kailun Yan, Jiawen Li, Kexin Zhang, Menglu Liu, Pei Zhu, Xiaofang Tang, Deshan Yuan, Yuejin Yang, Runlin Gao, Jinqing Yuan, Xueyan Zhao   +10 more
doaj   +2 more sources

Apolipoprotein A-I and A-I mimetic peptides: a role in atherosclerosis

Journal of Inflammation Research, 2011
Godfrey S Getz, Catherine A ReardonThe University of Chicago, Department of Pathology, Chicago, IL, USAAbstract: Cardiovascular disease remains a major cause of morbidity and mortality in the westernized world.
Getz GS, Reardon CA
doaj   +1 more source

Lecithin:cholesterol acyltransferase binds a discontinuous binding site on adjacent apolipoprotein A-I belts in HDL. [PDF]

J Lipid Res
Coleman B, Bedi S, Hill JH, Morris J, Manthei KA, Hart RC, He Y, Shah AS, Jerome WG, Vaisar T, Bornfeldt KE, Song H, Segrest JP, Heinecke JW, Aller SG, Tesmer JJG, Davidson WS.   +16 more
europepmc   +2 more sources

Trypsin Partially Cleaves Apolipoprotein A-I (ApoA-I) Precursor into Mature ApoA-I Hindering the Quantification of Naturally Occurring ApoA-I Proteoforms by Liquid Chromatography in Multiple Reaction Monitoring Mode Mass Spectrometry (LC-MRM-MS). [PDF]

J Am Soc Mass Spectrom
Llorens-Cebrià C, Núñez-Seral N, Villena-Ortiz Y, Martínez-Díaz I, Soler MJ, Ferrer-Costa R, Jacobs-Cachá C, López-Hellín J.   +7 more
europepmc   +2 more sources

LCAT cholesterol esterification is associated with the increase of ApoE/ApoA-I ratio during atherosclerosis progression in rabbit [PDF]

, 2011
Apolipoprotein A-I and Apolipoprotein E promote different steps of reverse cholesterol transport, including lecithin-cholesterol acyltransferase stimulation.
A. Carlucci, L. Cigliano, B. Maresca, M. S. Spagnuolo, G. Di Salvo, R. Calabrò, P. Abrescia   +6 more
core   +2 more sources

The apolipoprotein B and apolipoprotein A-I Ratio serves as a strong prognostic factor for the overall survival of patients with colorectal cancer

Frontiers in Oncology, 2023
BackgroundThe lipid metabolism status of patients with colorectal cancer (CRC) has not been understood comprehensively. The present study investigated the characteristics of lipid metabolism parameters in CRC patients with or without metastases and ...
Yangxun Pan, Yangxun Pan, Yangxun Pan, Zhiwei Ye, Zhiwei Ye, Yihong Ling, Yihong Ling, Lingheng Kong, Lingheng Kong, Chenwei Wang, Chenwei Wang, Gong Chen, Gong Chen, Desen Wan, Desen Wan, Minshan Chen, Minshan Chen, Dandan Hu, Dandan Hu   +18 more
doaj   +1 more source

Association between the ratio of high-density lipoprotein cholesterol to apolipoprotein A-I and in-stent neoatherosclerosis: an optical coherence tomography study. [PDF]

Cardiovasc Diagn Ther
Gu N, Zeng Y, Long X, Liu Z, Wang Z, Zhang W, Yang D, Yuan J, Chen L, Zhao R, Shi B.   +10 more
europepmc   +2 more sources

Correlation between Pretreatment Serum Apolipoprotein Level and Prognosis of Small Cell Lung Cancer Patients

Chinese Journal of Lung Cancer, 2020
Background and objective Lung cancer is the leading cause of cancer-related death, and small cell lung cancer (SCLC) has a poor prognosis in all types of lung cancer.
Ya DONG, Haocheng WANG, Dongfeng SHAN, Linwei ZHANG, Zhuang YU   +4 more
doaj   +1 more source

Apolipoprotein Mimetic Peptides: A New Approach for the Treatment of Asthma

Frontiers in Pharmacology, 2012
New treatments are needed for severe asthmatics to improve disease control and avoid severe toxicities associated with oral corticosteroids. We have used a murine model of house dust mite (HDM)-induced asthma to identify steroid-unresponsive genes that ...
Xianglan eYao, Michael P. Vitek, Alan T. Remaley, Stewart J. Levine   +3 more
doaj   +1 more source