Results 121 to 130 of about 18,522 (215)

IMMUNOCHEMICAL CHARACTERIZATION OF 6 MONOCLONAL-ANTIBODIES TO HUMAN APOLIPOPROTEIN-A-I - EPITOPE MAPPING AND EXPRESSION

, 1990
We have produced and characterized six urine monoclonal antibodies to human apolipoprotein A-I named A-I-9, A-I-12, A-I-15, A-I-16, A-I-19, and A-I-57. All monoclonal antibodies were specific for apolipoprotein A-I and bound between 55% and 100% of 125I ...
A. CATAPANO, A. ZOPPO, G. FRANCESCHINI, S. MARCOVINA, S. FANTAPPIE   +4 more
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AAV gene therapy as a means to increase apolipoprotein (Apo) A-I and high-density lipoprotein-cholesterol levels: correction of murine ApoA-I deficiency

, 2009
BACKGROUND: Inherited apolipoprotein (Apo) A-I deficiency is an orphan disorder characterized by high-density lipoprotein (HDL)-cholesterol deficiency and premature atherosclerosis.
Beattie, Stuart G, Comijn, Elisabeth M, Sierts, Jeroen A., van den Oever, Karin, Twisk, Jaap, Veldman, Robert Jan, Vaessen, Stefan F. C., Sierts, Jeroen A, Kuivenhoven, Jan Albert, Comijn, Elisabeth M., Vaessen, Stefan F C, Snapper, Jolanda, Beattie, Stuart G.   +12 more
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Molecular characterization and developmental expression patterns of apolipoprotein a-i in senegalese sole (solea senegalensis kaup)

, 2016
The apolipoprotein A-I (ApoA-I) is an essential component of the high density lipoproteins (HDL). In this study, the cDNA and genomic sequences of this apolipoprotein were characterized for first time in Solea senegalensis.
Rodríguez-Rúa, A. (Ana), Manchado, M. (Manuel), Hachero-Cruzado, I. (Ismael), Manchado, Manuel, Román-Padilla, J. (Javier), Rodríguez-Rúa, Ana, Hachero-Cruzado, Ismael, Román-Padilla, Javier   +7 more
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Apolipoprotein A-I induced amyloidosis

, 1998
Amyloidosis is characterized by extracellular deposits of protein fibrils with a high content of β-sheets in secondary structure. The protein forms together with proteoglycans amyloid fibrils causing organ damage and serious morbidity.
Marcus J Pröpsting, Genschel, Janine, Schmidt, Hartmut H.-J, Regina Haas, Pröpsting, Marcus J, Hartmut H.-J Schmidt, Janine Genschel, Haas, Regina   +7 more
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Secretion of lipoproteins, apolipoprotein A-I and apolipoprotein E by isolated and perfused liver of rat with experimental nephrotic syndrome.

, 1981
Nephrotic syndrome induced in the rat by the administration of puromycin aminonucleoside is accompanied by a hyperlipoproteinemia characterized by an elevation of all plasma lipoproteins, particularly of VLDL (1.006 g/ml) and HDL1 (1.050-1.090 g/ml). The
Bartosek I., Fainaru M, CALANDRA BUONAURA, Sebastiano, Gherardi E, Guaitani A   +4 more
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Apolipoprotein A-II Production Rate Is a Major Factor Regulating the Distribution of Apolipoprotein A-I Among HDL Subclasses LpA-I and LpA-I:A-II in Normolipidemic Humans

, 1995
HDLs are heterogeneous in their apolipoprotein composition. Apolipoprotein (apo) A-I and apoA-II are the major proteins found in HDL and form the two major HDL subclasses: those that contain only apoA-I (LpA-I) and those that contain both apoA-I and apoA-
Katsunori Ikewaki, Daniel J. Rader, Loren A. Zech, H. Bryan Brewer, Marie Kindt   +4 more
core   +1 more source

Haptoglobin Influences ApoA-I Activities in Reverse Cholesterol Transport.

, 2008
Aims: Apolipoprotein A-I (ApoA-I), the major apolipoprotein of the high density lipoprotein (HDL), plays key roles in the removal of cholesterol excess from peripheral cells, in a recognized anti-atherosclerotic process called “reverse cholesterol ...
CIGLIANO, LUISA, A. Dalessio, A. Carlucci, E. Picardi, A. Salvatore, B. Maresca, C. R. Pugliese, E. Santoro, ABRESCIA, PAOLO   +8 more
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Evidence That Apolipoprotein A-I _Milano Has Reduced Capacity, Compared With Wild-Type Apolipoprotein A-I, to Recruit Membrane Cholesterol

, 1997
Human carriers of apolipoprotein (apo) A-I Milano are heterozygous for an Arg 173 →Cys substitution in the apoA-I primary sequence; despite severe reductions in HDL cholesterol concentrations, affected ...
Trudy M. Forte, Lori J. Stoltzfus, Amir Ravandi, Edward M. Rubin, Mark R. McCall, Arnis Kuksis, John K. Bielicki   +6 more
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Chameleon ‘aggregation-prone’ segments of apoA-I: A model of amyloid fibrils formed in apoA-I amyloidosis

, 2015
Apolipoprotein A-I (apoA-I) is the major component of high density lipoproteins and plays a vital role in reverse cholesterol transport. Lipid-free apoA-I is the main constituent of amyloid deposits found in atherosclerotic plaques, an acquired type of ...
Louros, N.N., Tsiolaki, P.L., Howlett, G.J., Iconomidou, V.A., Hamodrakas, S.J., Griffin, M.D.   +5 more
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Bone Marrow Transplantation Shows Superior Atheroprotective Effects of Gene Therapy With Apolipoprotein A-I Milano Compared With Wild-Type Apolipoprotein A-I in Hyperlipidemic Mice

, 2006
ObjectivesWe tested the hypothesis that gene therapy using apolipoprotein A-I Milano (apoA-IMilano) is more effective than that using wild-type apolipoprotein A-I (apoA-I) in reducing atherosclerosis.BackgroundApolipoprotein A-I Milano is a naturally ...
Shah, Prediman K., Song, Lei, Pan, Theresa, Wang, Lai, Yukht, Ada, Sharifi, Behrooz G.   +5 more
core   +1 more source