Results 31 to 40 of about 18,522 (215)

Apolipoprotein A-II influences apolipoprotein E-linked cardiovascular disease risk in women with high levels of HDL cholesterol and C-reactive protein. [PDF]

PLoS ONE, 2012
BACKGROUND: In a previous report by our group, high levels of apolipoprotein E (apoE) were demonstrated to be associated with risk of incident cardiovascular disease in women with high levels of C-reactive protein (CRP) in the setting of both low ...
James P Corsetti, Stephan J L Bakker, Charles E Sparks, Robin P F Dullaart   +3 more
doaj   +1 more source

Kinetic characteristics and regulation of HDL cholesteryl ester and apolipoprotein transport in the apoA-I-/- mouse [PDF]

Journal of Lipid Research, 1998
The concentration dependence and tissue distribution of high density lipoprotein (HDL) cholesteryl ester and apolipoprotein (apo) transport were determined in apoA-I knockout mice (apoA-I-/-) that lack normal HDL in plasma. Rates of HDL cholesteryl ester clearance were highly sensitive to plasma HDL cholesteryl ester concentrations with clearance rates
David K. Spady, Laura A. Woollett, Robert S. Meidell, Helen H. Hobbs   +3 more
openaire   +3 more sources

Apolipoprotein A-I promotes cholesterol release and apolipoprotein E recruitment from THP-1 macrophage-like foam cells

Journal of Lipid Research, 1999
Apolipoprotein E (apoE) is synthesized and secreted by arterial macrophages while apolipoprotein A-I (apoA-I) is present in surrounding interstitial fluids.
John K. Bielicki, Mark R. McCall, Trudy M. Forte   +2 more
doaj   +1 more source

Adenoviral vector-mediated overexpression of serum amyloid A in apoA-I-deficient mice

Journal of Lipid Research, 1997
Serum amyloid A (SAA) is an acute phase reactant that can become the predominant apolipoprotein of high density lipoprotein (HDL) during severe inflammatory states. However, the function of SAA is unknown.
N R Webb, M C de Beer, D R van der Westhuyzen, M S Kindy, C L Banka, K Tsukamoto, D L Rader, F C de Beer   +7 more
doaj   +1 more source

In vivo metabolism of apolipoprotein A-I on high density lipoprotein particles LpA-I and LpA-I,A-II.

Journal of Lipid Research, 1991
Apolipoprotein (apo) A-I is the major protein in high density lipoproteins (HDL) and is found in two major subclasses of lipoproteins, those containing apolipoprotein A-II (termed LpA-I,A-II) and those without apoA-II (termed LpA-I). The in vivo kinetics
DJ Rader, G Castro, LA Zech, JC Fruchart, HB Brewer, Jr   +4 more
doaj   +1 more source

Formation of high density lipoproteins containing both apolipoprotein A-I and A-II in the rabbit

Journal of Lipid Research, 2006
Human plasma HDLs are classified on the basis of apolipoprotein composition into those that contain apolipoprotein A-I (apoA-I) without apoA-II [(A-I)HDL] and those containing apoA-I and apoA-II [(A-I/A-II)HDL]. ApoA-I enters the plasma as a component of
Neil J. Hime, Kate J. Drew, Kevin Wee, Philip J. Barter, Kerry-Anne Rye   +4 more
doaj   +1 more source

On the hepatic mechanism of HDL assembly by the ABCA1/apoA-I pathway

Journal of Lipid Research, 2005
The mechanism for the assembly of HDL with cellular lipid by ABCA1 and helical apolipoprotein was investigated in hepatocytes. Both HepG2 cells and mouse primary culture hepatocytes produced HDL with apolipoprotein A-I (apoA-I) whether endogenously ...
Maki Tsujita, Cheng-Ai Wu, Sumiko Abe-Dohmae, Shinichi Usui, Mitsuyo Okazaki, Shinji Yokoyama   +5 more
doaj   +1 more source

A cDNA-dependent scintillation proximity assay for quantifying apolipoprotein A-I

Journal of Lipid Research, 1997
We have developed a cDNA-dependent scintillation proximity assay (SPA) for rabbit apolipoprotein A-I that follows a classic radioimmunoassay scheme, in that antiserum and radiolabeled ligand are used in a process to quantify a source containing unlabeled
J C Hanselman, D A Schwab, T J Rea, C L Bisgaier, M E Pape   +4 more
doaj   +1 more source

Structural and dynamic features of apolipoprotein A-I cysteine mutants, Milano and Paris, in synthetic HDL

, 2010
Pursuing an established research interest in our group, we built two models for synthetic HDL containing the natural cysteine mutants of apolipoprotein A-I, apolipoprotein A-I Milano (apoA-IM) and apolipoprotein A-I Paris (apoA-IP), both in their ...
C. Sirtori, Cesare R. Sirtori, Cristina Sensi, L. Calabresi, G. Franceschini, Alessandro Guerini Rocco, Elisabetta Gianazza, E. Gianazza, I. Eberini, A. Guerini Rocco, C. Sensi, Laura Calabresi, Ivano Eberini, Guido Franceschini   +13 more
core   +1 more source

Allelic drop-out may occur with a primer binding site polymorphism for the commonly used RFLP assay for the -1131T>C polymorphism of the Apolipoprotein AV gene. [PDF]

, 2006
Apolipoprotein AV (ApoAV) gene variant, -1131T>C, is associated with increased triglyceride concentrations in all ethnic groups studied. An MseI based RFLP analysis is the most commonly used method for genotyping this SNP.
Andrew T Hattersley, Venigalla, Prathyusha NS, Kirsten J Ward, Ward Kirsten J, Hattersley, Andrew T, Ward, Kirsten J, Giriraj R Chandak, Ellard Sian, Timothy M Frayling, Prathyusha NS Venigalla, Frayling, Timothy M, Sian Ellard, Chittaranjan S Yajnik, Hattersley Andrew T, Chandak Giriraj R, Frayling Timothy M, Yajnik Chittaranjan S, Chandak, Giriraj R, Venigalla Prathyusha NS, Ellard, Sian, Yajnik, Chittaranjan S   +20 more
core   +1 more source