Results 41 to 50 of about 18,522 (215)

Apolipoprotein A (ApoA) in Neurological Disorders: Connections and Insights [PDF]

International Journal of Molecular Sciences
Patrick G Burgon, Rafif Mahmood Al Saady, Shona Pedersen   +2 more
exaly   +2 more sources

Structural features and dynamics properties of human apolipoprotein A-I in a model of synthetic HDL

, 2009
High-density lipoproteins (HDL) play a major role in the reverse transport of cholesterol and have antiatherogenic activities. Their major protein component is apolipoprotein (apo) A-I.
E. GIANAZZA, C.R. SIRTORI, C. SENSI, G. FRANCESCHINI, I. EBERINI, A. GUERINI ROCCO, L. CALABRESI   +6 more
core   +1 more source

Characterization of four lipoprotein classes in human cerebrospinal fluid

Journal of Lipid Research, 2001
Lipoprotein metabolism in brain has not yet been fully elucidated, although there are a few reports concerning lipids in the brain and lipoproteins and apolipoproteins in the cerebrospinal fluid (CSF).
Stefanie Koch, Nicolette Donarski, Kathrin Goetze, Miriam Kreckel, Hans-Joerg Stuerenburg, Carsten Buhmann, Ulrike Beisiegel   +6 more
doaj   +1 more source

Association Between ApoA-I (Apolipoprotein A-I) Immune Complexes and Adverse Cardiovascular Events—Brief Report [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2019
Objective: The immune response is linked to the progression of atherosclerotic cardiovascular disease (CVD). Free autoantibodies targeting ApoA-I (apolipoprotein A-I) have been identified as a component of the inflammatory milieu in patients and have a moderate association with CVD progression.
David, Henson, Ayman Samman, Tahhan, David, Nardo, Arshed Ali, Quyyumi, Vincent J, Venditto   +4 more
openaire   +2 more sources

Quality control in the apoA-I secretory pathway

Journal of Lipid Research, 2004
From a total of 47 known apolipoprotein A-I (apoA-I) mutations, only 18 are linked to low plasma HDL apoA-I concentrations, and 78% of these map to apoA-I helices 6 and 7 (residues 143–186).
Shaila Bhat, Manal Zabalawi, Mark C. Willingham, Gregory S. Shelness, Michael J. Thomas, Mary G. Sorci-Thomas   +5 more
doaj   +1 more source

Human apolipoprotein A-I isoprotein metabolism: proapoA-I conversion to mature apoA-I.

Journal of Lipid Research, 1985
ProapoA-I (apoA-i+2 isoform) is the major apoA-I isoprotein secreted by the liver and intestine; however, it is a minor isoprotein in plasma and lymph where the major A-I apo-lipoprotein is mature apoA-I (apoA-I0, apoA-I-1, and apoA-I-2 isoforms). In the present report we provide evidence that apoA-I is rapidly and quantitatively converted to mature ...
D Bojanovski, R E Gregg, G Ghiselli, E J Schaefer, J A Light, H B Brewer, Jr   +5 more
openaire   +3 more sources

Exercise‐specific plasma proteomic signatures in racehorses: Candidates for training adaptation and peak load monitoring

Equine Veterinary Journal, EarlyView.
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka, Bianka Świderska, Ewa Sitkiewicz, Izabela Dąbrowska, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Structural determinants in ApoA-I amyloidogenic variants explain improved cholesterol metabolism despite low HDL levels. [PDF]

, 2017
Twenty Apolipoprotein A-I (ApoA-I) variants are responsible for a systemic hereditary amyloidosis in which protein fibrils can accumulate in different organs, leading to their failure.
Iacobucci, I, Domingo-Espín, Joan, Nilsson, O, Oktawia Nilsson, Domingo espín, J, Del Giudice, Rita, Lagerstedt, Jens O, Iacobucci, Ilaria,, Monti, Dm, Lagerstedt, Jens O,, Lagerstedt, Jo, Iacobucci, Ilaria, Joan Domingo-Espín, Nilsson, Oktawia, Nilsson, Oktawia,, Daria Maria Monti, Monti, Daria Maria,, Del Giudice, R, Jens O. Lagerstedt, Maria Monti, Monti, Daria Maria, MONTI, MARIA, Monti, Maria Cristina, Rita Del Giudice, Ilaria Iacobucci, Domingo-Espín, Joan,, Monti, Maria Cristina,, Lund University., Del Giudice, Rita,   +28 more
core   +1 more source

Apolipoprotein gene expression in the rabbit: abundance, size, and distribution of apolipoprotein mRNA species in different tissues

Journal of Lipid Research, 1988
We have used human apolipoprotein cDNAs as hybridization probes to study the relative abundance and distribution of apolipoprotein mRNAs in rabbit tissues by RNA blotting analysis.
C Lenich, P Brecher, S Makrides, A Chobanian, V I Zannis   +4 more
doaj   +1 more source

Inhibition of collar-induced carotid atherosclerosis by recombinant apoA-I cysteine mutants in apoE-deficient mice[S]

Journal of Lipid Research, 2010
The previous studies in our laboratory revealed that seven cysteine mutants of apolipoprotein A-I (apoA-I) have different structural features and biological activities in vitro and in vivo.
Xinbo Zhang, Xuewei Zhu, Baosheng Chen
doaj   +1 more source