Results 21 to 30 of about 18,522 (215)

ApoA-I deficiency in mice is associated with redistribution of apoA-II and aggravated AApoAII amyloidosis[S]

Journal of Lipid Research, 2011
Apolipoprotein A-II (apoA-II) is the second major apolipoprotein following apolipoprotein A-I (apoA-I) in HDL. ApoA-II has multiple physiological functions and can form senile amyloid fibrils (AApoAII) in mice.
Yaoyong Wang (王耀勇), Jinko Sawashita (澤下仁子), Jinze Qian (钱金泽), Beiru Zhang (张蓓茹), Xiaoying Fu (付笑影), Geng Tian (田耕), Lei Chen (陈磊), Masayuki Mori (森 政之), Keiichi Higuchi (樋口京一)   +8 more
doaj   +1 more source

Mass kinetics of apolipoprotein A-I in interstitial fluid after administration of intravenous apolipoprotein A-I/lecithin discs in humans

Journal of Lipid Research, 2006
Apolipoprotein kinetics are customarily determined by modeling time curves of specific radioactivity or isotopic enrichment in plasma after intravenous infusion of radiolabeled lipoproteins or stable isotope-enriched amino acids.
Roman Hovorka, M. Nazeem Nanjee, C. Justin Cooke, Irina P. Miller, Waldemar L. Olszewski, Norman E. Miller   +5 more
doaj   +1 more source

Intracellular apoA-I and apoB distribution in rat intestine is altered by lipid feeding.

Journal of Lipid Research, 1988
Intracellular forms of chylomicrons, very low density lipoprotein (VLDL) and high density lipoprotein (HDL) have previously been isolated from the rat intestine.
A M Magun, B Mish, R M Glickman
doaj   +1 more source

High density lipoprotein particle size restriction in apolipoprotein A-I(Milano) transgenic mice

Journal of Lipid Research, 1997
Human carriers of apolipoprotein A-I(Milano) (Arg173 –> Cys substitution in apolipoprotein A-I) are characterized by an HDL deficiency in which small, dense HDL accumulate in plasma.
J K Bielicki, T M Forte, M R McCall, L J Stoltzfus, G Chiesa, C R Sirtori, G Franceschini, E M Rubin   +7 more
doaj   +1 more source

Tissue-specific expression of apolipoprotein A-I (ApoA-I) is regulated by the 5′-flanking region of the human ApoA-I gene.

Journal of Biological Chemistry, 1988
We have isolated and characterized a 2.5-kilobase pairs genomic DNA fragment which includes the 5'-flanking region and the first and second exons of the human apolipoprotein (apo) A-I gene. The major transcriptional start site was determined by primer extension analysis and is 235 base pairs (bp) upstream from the AUG translational start codon in liver
K, Higuchi, S W, Law, J M, Hoeg, U K, Schumacher, N, Meglin, H B, Brewer   +5 more
openaire   +2 more sources

Mass spectrometric determination of apolipoprotein molecular stoichiometry in reconstituted high density lipoprotein particles[S]

Journal of Lipid Research, 2009
Plasma HDL-cholesterol and apolipoprotein A-I (apoA-I) levels are strongly inversely associated with cardiovascular disease. However, the structure and protein composition of HDL particles is complex, as native and synthetic discoidal and spherical HDL ...
John B. Massey, Henry J. Pownall, Stephen Macha, Jamie Morris, Matthew R. Tubb, R.A.Gangani D. Silva   +5 more
doaj   +1 more source

Prebeta-migrating high density lipoprotein: quantitation in normal and hyperlipidemic plasma by solid phase radioimmunoassay following electrophoretic transfer.

Journal of Lipid Research, 1987
A quantitative solid phase immunoassay has been developed for the determination of the mass of electrophoretically separated prebeta apolipoprotein A-I (apoA-I) in human plasma.
B Y Ishida, J Frolich, C J Fielding
doaj   +1 more source

IgG anti-apolipoprotein A-1 antibodies in patients with systemic lupus erythematosus are associated with disease activity and corticosteroid therapy: an observational study. [PDF]

, 2015
IgG anti-apolipoprotein A-1 (IgG anti-apoA-1) antibodies are present in patients with systemic lupus erythematosus (SLE) and may link inflammatory disease activity and the increased risk of developing atherosclerosis and cardiovascular disease (CVD) in ...
Davari, M, Yiannis Ioannou, Isenberg, D, Paul Bassett, Rahman, A, David Isenberg, Anisur Rahman, Maria Davari, Alber, KF, Ioannou, Y, Oliver Leach, Giles, I, Bassett, P, Karim Alber, Ian Giles, Leach, O, Sara Croca, Chambers, S, Croca, S, Sharon Chambers   +19 more
core   +1 more source

Gain and loss events in the evolution of the apolipoprotein family in vertebrata

BMC Evolutionary Biology, 2019
Background Various apolipoproteins widely distributed among vertebrata play key roles in lipid metabolism and have a direct correlation with human diseases as diagnostic markers.
Jia-Qian Liu, Wen-Xing Li, Jun-Juan Zheng, Qing-Nan Tian, Jing-Fei Huang, Shao-Xing Dai   +5 more
doaj   +1 more source

Apolipoprotein A-I conformation markedly influences HDL interaction with scavenger receptor BI

Journal of Lipid Research, 2001
Apolipoprotein A-I (apoA-I) is an important ligand for the high density lipoprotein (HDL) scavenger receptor class B type I (SR-BI). SR-BI binds both free and lipoprotein-associated apoA-I, but the effects of particle size, composition, and ...
M.C. de Beer, D.M. Durbin, L. Cai, A. Jonas, F.C. de Beer, D.R. van der Westhuyzen   +5 more
doaj   +1 more source