Results 81 to 90 of about 2,196 (157)

Role of enterocyte stearoyl-Co-A desaturase-1 in LDLR-null mice

Journal of Lipid Research, 2018
After crossing floxed stearoyl-CoA desaturase-1 (Scd1fl/fl) mice with LDL receptor-null (ldlr−/−) mice, and then Villin Cre (VilCre) mice, enterocyte Scd1 expression in Scd1fl/fl/ldlr−/−/VilCre mice was reduced 70%. On Western diet (WD), Scd1fl/fl/ldlr−/−
Pallavi Mukherjee, Greg Hough, Arnab Chattopadhyay, Victor Grijalva, Ellen Ines O'Connor, David Meriwether, Alan Wagner, James M. Ntambi, Mohamad Navab, Srinivasa T. Reddy, Alan M. Fogelman   +10 more
doaj   +1 more source

An apoA-I mimetic peptide facilitates off-loading cholesterol from HDL to liver cells through scavenger receptor BI

International Journal of Biological Sciences, 2009
Apolipoprotein A-I (apoA-I) mimetic peptides have been pursued as new therapeutic agents for the treatment of atherosclerosis, yet their precise mechanism responsible for atheroprotection remains unclear.
Xuelei Song, Paul Fischer, Xun Chen, Charlotte Burton, Jun Wang
doaj  

Potential restoration of HDL function with apolipoprotein A-I mimetic peptide in end-stage renal disease [PDF]

Kidney International, 2009
High-density lipoprotein (HDL) cholesterol level is low in dialysis patients. The HDL that is present is dysfunctional, failing to protect low-density lipoprotein (LDL) from oxidation and reduce levels of oxidized LDL. Addition of the orally absorbable amphipathic peptide 4-F to LDL obtained from dialysis patients protects LDL from oxidation in vitro ...
openaire   +2 more sources

Incorporation of α-methylated amino acids into Apolipoprotein A-I mimetic peptides improves their helicity and cholesterol efflux potential. [PDF]

Biochem Biophys Res Commun, 2020
Islam R, Sviridov DO, Drake SK, Tunyi J, Abdoulaeva G, Freeman LA, Pastor RW, Remaley AT.   +7 more
europepmc   +1 more source

Molecular Dynamic Simulations of Apolipoprotein A-I peptide Mimetics [PDF]

Biophysical Journal, 2011
Plain, Amanda M., Patterson, James C.
openaire   +1 more source

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

High‐density lipoprotein in diabetes: Structural and functional relevance

Journal of Diabetes Investigation
Low levels of high‐density lipoprotein‐cholesterol (HDL‐C) is considered a major cardiovascular risk factor. However, recent studies have suggested a more U‐shaped association between HDL‐C and cardiovascular disease.
David Tak Wai Lui, Kathryn Choon Beng Tan   +1 more
doaj   +1 more source

ISEV2026 Abstract Book

Journal of Extracellular Vesicles, Volume 15, Issue S1, June 2026.
wiley   +1 more source

High-density lipoprotein, and apolipoprotein A-I: a regulatory role and novel therapeutic strategies for the treatment atherosclerosis

Атеросклероз, 2013
In the review show the functions of high-density lipoprotein, is not related to the exchange of lipids within them. The results own research, as well as literary evidenced of the important regula tory role. Regulatory effect of HDL is closely related to
L. M. Polyakov, L. E. Panin
doaj  

Characterization of apolipoprotein A-I peptide phospholipid interaction and its effect on HDL nanodisc assembly

International Journal of Nanomedicine, 2019
Hiren Patel,1 Bei Ding,2 Kelsey Ernst,3 Lei Shen,2 Wenmin Yuan,3 Jie Tang,3 Lindsey R Drake,1 Jukyung Kang,3 Yaoxin Li,2 Zhan Chen,2 Anna Schwendeman1,3,41Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor, MI, USA;
Patel H, Ding B, Ernst K, Shen L, Yuan W, Tang J, Drake LR, Kang J, Li Y, Chen Z, Schwendeman A   +10 more
doaj