Results 181 to 190 of about 803,874 (212)

Apolipoprotein A-II, HDL metabolism and atherosclerosis.

Atherosclerosis, 2002
Apolipoprotein (Apo) A-I and apo A-II are the major apolipoproteins of HDL. It is clearly demonstrated that there are inverse relationships between HDL-cholesterol and apo A-I plasma levels and the risk of coronary heart disease (CHD) in the general population.
A. Tailleux, P. Duriez, J. Fruchart, V. Clavey   +3 more
semanticscholar   +3 more sources

Atherosclerosis in transgenic mice overexpressing apolipoprotein A-II.

Science, 1993
Concentrations of plasma high density lipoprotein (HDL) are inversely correlated with atherosclerotic coronary artery disease. The two most abundant protein constituents of HDL are apolipoproteins A-I and A-II (apoA-I and apoA-II). ApoA-I is required for assembly of HDL and, when overexpressed in transgenic mice, confers resistance to early ...
Craig H. Warden, C. Hedrick, J. Qiao, L. Castellani, A. Lusis   +4 more
semanticscholar   +3 more sources

In vitro interaction of human HDL with human apolipoprotein A-II. Synthesis of apolipoprotein A-II-rich HDL.

Biochimica et biophysica acta, 1981
The aim of this study was to define the specific affinity of human apolipoproteins A-I and A-II for HDL lipids and to investigate the possible transfer of apolipoproteins from the HDL molecule. For this purpose we incubated human HDL with increasing amounts of isolated apolipoprotein A-II.
P. van Tornout, H. Caster, M. Lievens, M. Rosseneu, G. Assmann   +4 more
semanticscholar   +3 more sources

Apolipoprotein A-II accelerates reactive AA amyloidosis

Amyloid, 2017
During the acute-phase response (APR), there is a dramatic increase in serum amyloid A (SAA) circulating in the blood in high-density lipoproteins (HDL).
Mu, Yang, Yingye, Liu, Lin, Li, Hiroki, Miyahara, Xin, Ding, Jian, Dai, Jinko, Sawashita, Masayuki, Mori, Keiichi, Higuchi   +8 more
openaire   +2 more sources

Apolipoprotein A-II modulates HDL remodeling in plasma

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1992
Native and reduced-carboxamidomethylated (RCM) HDL3 are incubated with a lipoprotein-depleted plasma fraction in the presence of triacylglycerol-rich particles isolated from Intralipid. Unmodified HDL3 are mainly converted into large HDL2b particles (diameter: 9.84 +/- 0.15 nm); RCM-HDL3 are transformed into both large HDL2b (9.76 +/- 0.10 nm) and ...
L. CALABRESI, C. BANFI, C. SIRTORI, G. FRANCESCHINI   +3 more
openaire   +2 more sources

Plasma Factors Required for Human Apolipoprotein A-II Dimerization

Biochemistry, 2004
Although plasma high-density lipoproteins (HDL) have been implicated in several cardioprotective pathways, the physiologic role of apolipoprotein (apo) A-II, the second most abundant of the HDL proteins, remains ambiguous. Human apo A-II is distinguished from most other species by a single cysteine (Cys6), which forms a disulfide bond with other ...
Baiba Kurins, Gillard, Y-S Amber, Chen, John W, Gaubatz, John B, Massey, Henry J, Pownall   +4 more
openaire   +2 more sources

Apolipoproteins A‐I and A‐II downregulate neutrophil functions

Lipids, 2002
AbstractThis work reports the effect of the apolipoproteins A‐I and A‐II (apoA‐I and apoA‐II) on the release of tumor necrosis factor (TNF)‐α, interleukin (IL)‐1β, IL‐8, and IL‐1 receptor antagonist (IL‐1Ra) and on the oxidative burst of human neutrophils.
Cristiane Jaciara, Furlaneto, Fernanda Pereira, Ribeiro, Elaine, Hatanaka, Glaucia Mendes, Souza, Marco A, Cassatella, Ana, Campa   +5 more
openaire   +2 more sources

Plasma apolipoprotein concentrations in familial apolipoprotein A-I and A-II deficiency (Tangier disease)

Metabolism, 1981
Familial apolipoprotein A-I and A-II deficiency (Tangier disease) is characterized by cholesterol ester deposition in histiocytes, decreased plasma cholesterol and low density lipoprotein cholesterol (C-LDL), and a striking deficiency of high density lipoproteins (HDL).
P, Alaupovic, E J, Schaefer, W J, McConathy, J D, Fesmire, H B, Brewer   +4 more
openaire   +2 more sources

Apolipoprotein A-Ii Gene Structure: Evolutionary Implications

1985
Abstract We present the complete nucleotide sequence of human apolipoprotein (apo) A-II cDNA cloned in plasmid. Using the cloned DNA as a hybridization probe, we localized the gene for apoA-II to chromosome 1 by Southern blot analysis of human-hamster somatic cell hybrids.
Y.K. TSAO, M.N. MOORE, LAWRENCE CHAN, C.C. LUO, W.H. LI, F.T. KAO   +5 more
openaire   +1 more source