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Multifunctional metabolic role of apolipoprotein A-II

Trends in Endocrinology and Metabolism, 2001
Men with a particular polymorphism of the gene encoding apolipoprotein A-II (apoA-II) have small waist circumference and enhanced metabolism of triglycerides, offering clues to the function of apoA-II.Ferdinand van't Hooft and colleagues investigated the role of apoA-II, a major structural protein of plasma high-density lipoproteins and whose function ...
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Plasma, apolipoprotein A‐I and A‐II levels in hyperlipidemia

Lipids, 1978
AbstractSome of the component moieties of high denisty lipoproteins (HDL) were analyzed in normal subjects and in patients with hyperlipidemia. Apoproteins A‐I and A‐II were quantified by radioimmunoassay, HDL cholesterol and triglycerides were assessed on heparin‐MnCl2 supernates of fasting plasmas.
G, Schonfeld, A, Bailey, R, Steelman
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A purification method for apolipoprotein A-I and A-II

Analytical Biochemistry, 1989
Apolipoproteins A-I and A-II were isolated from precipitates obtained by cold ethanol fractionation of human plasma. The starting material used in this report was precipitate B of the Kistler and Nitschmann method which corresponds approximately to fraction III of the Cohn and Oncley procedure.
M C, Peitsch   +5 more
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The concentration of apolipoprotein A-II in human peripheral lymph

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1989
The concentration of apolipoprotein A-I (apoA-I) and of apolipoprotein A-II (apoA-II) was determined immunoelectrophoretically in lymph and plasma of six subjects. The concentration in lymph of apoA-I was 20.3 +/- 3.1 mg/dl, that of apoA-II was 4.6 +/- 0.5 mg/dl. The ratio of the concentration in lymph over that in plasma (CL/CP) for apoA-I was 0.14 +/-
D, Reichl, D N, Rudra, J, Pflug
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Serum apolipoprotein A-II, a biochemical indicator of alcohol abuse

Clinica Chimica Acta, 1984
The possible use of high density lipoprotein (HDL) cholesterol, HDL phospholipids, apolipoproteins (APO) A-I and A-II as markers of alcohol abuse was studied in 78 intemperate drinkers. The mean value for each of these parameters was higher in drinkers than in control subjects.
P, Puchois   +4 more
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Rosuvastatin selectively stimulates apolipoprotein A-I but not apolipoprotein A-II synthesis in Hep G2 cells

Metabolism, 2008
Hydroxymethylglutaryl-coenzyme A reductase inhibitors (statins) are extensively used to regulate dyslipidemia and to reduce atherosclerotic cardiovascular disease. In addition to effectively lowering cholesterol and low-density lipoprotein levels, rosuvastatin and certain other statins can also increase plasma high-density lipoprotein (HDL) cholesterol
Shucun, Qin   +4 more
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Kinetics of apolipoproteins A-I and A-II

1984
Plasma lipoproteins are a polydisperse collection of particles which range in diameter from 7 to 160 nm. These lipoproteins particles have been classified according to methods of separation1. One system, based on density, divides the lipoproteins into five classes: chylomicrons (ρ < 0.95), very-low-density lipoproteins (VLDL, 0.95 < ρ < 1.006 ...
L. Zech   +4 more
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Human Apolipoprotein A-I and A-II Metabolism

1987
Recognition of the inverse correlation between high density lipoprotein cholesterol levels and the development of premature cardiovascular disease have focused a great deal of interest on HDL (Miller and Miller 1975; Rhoads et al. 1976; Castelli et al. 1977).
H. B. Brewer   +4 more
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Metabolism of apolipoproteins A-I, A-II, and A-IV

1986
Publisher Summary Kinetic studies utilizing radioiodinated apolipoproteins have yielded important insights into lipoprotein metabolism. A major concern in these studies is that the tracer has identical kinetic behavior in vivo to native lipoproteins.
E J, Schaefer, J M, Ordovas
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