ABSTRACT Background Genetic clusters related to Type 2 diabetes (T2D) have differential impact on cardiovascular diseases (CVDs), although the underlying mechanisms, such as proteomic perturbation, remain unexplored. We conducted a network Mendelian randomisation (MR) study to identify proteomic mediators linking T2D genetic clusters and CVDs.
Shuang Liao +4 more
wiley +1 more source
Apolipoprotein B/Apolipoprotein A1 ratio is an independent prognostic factor in pancreatic cancer. [PDF]
Li C +6 more
europepmc +1 more source
Lipoprotein(a) and risk-weighted apolipoprotein B: a novel metric for atherogenic risk. [PDF]
Rehman MB, Tudrej BV.
europepmc +1 more source
Understanding and addressing resistance to IMiDs immunomodulatory compounds in multiple myeloma
IMiDs are pivotal in the treatment of multiple myeloma. Mechanisms of resistance comprise cell intrinsic and extrinsic pathways, involving tumour microenvironment, immune cell dysfunction, CRBN‐dependent and independent genetic drivers and epigenetic changes.
Maria‐Cynthia Fuentes‐Lacouture +3 more
wiley +1 more source
Low prevalence of testing for apolipoprotein B and lipoprotein (a) in the real world. [PDF]
Murdock DJ +6 more
europepmc +1 more source
Apolipoprotein B-48 and late graft failure in kidney transplant recipients. [PDF]
Szili-Torok T +5 more
europepmc +1 more source
Association between Apolipoprotein B and diabetic nephropathy: insights from the National Health and Nutrition Examination Survey 2007-2016 and Mendelian randomization analysis. [PDF]
Wang H +8 more
europepmc +1 more source
Concordance-discordance between apolipoprotein B and lipid biomarkers in predicting 20-year atherosclerotic cardiovascular disease risk: The ATTICA study (2002-2022). [PDF]
Giannakopoulou SP +8 more
europepmc +1 more source
Fasting plasma C-peptide correlates with body mass index, hsCRP, apolipoprotein B, and other atherogenic lipids in healthy individuals. [PDF]
Whiss PA, Baldimtsi E, Wahlberg J.
europepmc +1 more source
Mini-Review: Immunogenic epitopes in apolipoprotein B-100 for atheroprotective immunization. [PDF]
Gerdes N, Klingenberg R.
europepmc +1 more source

