Results 241 to 250 of about 123,719 (312)

Single‐Nucleus Multiomic Analysis Reveals Immune–Metabolic Reprogramming Consistent With Maladaptive Trained Immunity in HIV‐Associated Neurocognitive Disorders

Glia, Volume 74, Issue 8, August 2026.
Single‐nucleus multiomic profiling of postmortem brain reveals coordinated immune, metabolic, and epigenomic reprogramming in glia of people with HIV consistent with maladaptive trained immunity sustaining neuroinflammation in HAND. ABSTRACT HIV‐associated neurocognitive disorders (HAND) remain prevalent in people with HIV (PWH) despite effective ...
Siera Martinez, Anelia Horvath, Luke Johnson, Tatiana Pushkarsky, Larisa Dubrovsky, Daria Starosyla, Ashley Bastin, Dmitri Sviridov, Michael Bukrinsky   +8 more
wiley   +1 more source

Apolipoprotein B and Glycemic Dysregulation: New Predictors of Type 2 Diabetes in High-Cardiovascular-Risk Populations. [PDF]

J Pers Med
Bekbossynova M, Ivanova-Razumova T, Kali A, Sailybayeva A, Khamitov S, Daniyarova G, Akzholova K, Saliev T.   +7 more
europepmc   +1 more source

Plasma Membrane Remodeling During Microglial Activation: A Hypothesis Linking Microglial Shape and Lipid Droplet Formation

Glia, Volume 74, Issue 8, August 2026.
Microglial morphology changes in response to damage by Aβ and aging result in significant reductions in cell surface area. Transcriptomic analyses suggest that fatty acid synthesis and triacylglycerol formation drive redistribution of surface membrane into intracellular lipid droplets.
G. William Rebeck, Giorgi Shautidze, Jordy Sepulveda, Gracie S. Healey, Priyanka S. Narayan   +4 more
wiley   +1 more source

Serum Apolipoprotein B and B/A1 Ratio as Early Negative Biomarkers for OCT- and OCTA-Detected Retinal Changes in Diabetic Macular Edema. [PDF]

Clin Ophthalmol
Soedarman S, Julia M, Gondhowiardjo TD, Kurnia KH, Prasetya ADB, Triyoga IF, Sasongko MB.   +6 more
europepmc   +1 more source

Contrast Agents for Enhanced Bioimaging: A Comprehensive Review

ChemBioChem, Volume 27, Issue 13, 14 July 2026.
Contrast agents, especially those that are nanoparticle‐based, are revolutionizing bioimaging by enabling highly sensitive, specific, and early‐stage diagnosis of diseases like cancer, using clinical imaging modalities such as CT, MRI, PET, and SPECT.
Paulo Sérgio Taube, Donald Fernandes, Arthur Abinader Vasconcelos, Hugo de Campos Braga, Alan Kelbis Oliveira Lima, José Arnaldo Santana Costa, Karla Furtado Andriani, Ester da Cunha Meira Santos, Antonio Jorge Silva Araújo Junior, Hauster Maximiler Campos de Paula, Wallace Júnio Reis, Kashif Gul, Nida Wahab, Luis Carlos Resio, Elisa Kawana Leal dos Santos, Márcio Peres de Araujo, Matheus Allen P. da Silva, Juliana Paula da Silva   +17 more
wiley   +1 more source

Apolipoprotein B: Bridging the Gap Between Evidence and Clinical Practice. [PDF]

Circulation
De Oliveira-Gomes D, Joshi PH, Peterson ED, Rohatgi A, Khera A, Navar AM.   +5 more
europepmc   +1 more source

Natural History of Chronic Kidney Disease in Sickle Cell Disease

American Journal of Hematology, Volume 101, Issue 7, Page 1456-1477, July 2026.
ABSTRACT Kidney complications, referred to as nephropathy, develop early in sickle cell disease (SCD). In addition to its known morbidity, abundant data show that chronic kidney disease (CKD) is associated with an increased mortality risk in SCD. Increasing evidence suggests that the natural history of SCD nephropathy is progressive. Initial glomerular
Kenneth I. Ataga
wiley   +1 more source

Apolipoprotein B/Apolipoprotein A1 ratio is an independent prognostic factor in pancreatic cancer. [PDF]

Transl Oncol
Li C, Yang X, Zhong Y, Wang W, Jin X, Bian L, Wang X.   +6 more
europepmc   +1 more source

Associations of self‐reported obstructive sleep apnea with cognition and dementia risk in cognitively unimpaired middle‐aged adults

Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract INTRODUCTION Obstructive sleep apnea (OSA) is a potential risk factor for cognitive impairment and dementia; however, its contribution in midlife and interactions with APOE ε4 remain unclear. METHODS Participants were 2795 cognitively unimpaired, middle‐aged adults enrolled in the Healthy Brain Project. OSA status was determined by self‐report.
Gabriel T. Abdelmessih, Lisa Bransby, Hannah Cummins, Melinda L. Jackson, Yen Ying Lim   +4 more
wiley   +1 more source

Lipoprotein(a) and risk-weighted apolipoprotein B: a novel metric for atherogenic risk. [PDF]

Lipids Health Dis
Rehman MB, Tudrej BV.
europepmc   +1 more source