Results 231 to 240 of about 123,719 (312)

Vascular smooth muscle cell mechanotransduction: Pathways, phenotypes and emerging technologies

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Vascular smooth muscle cells are exposed to mechanical stimuli from the blood flow and the extracellular matrix. The cells sense the signals from cyclic stretch, shear stress, hydrostatic pressure and matrix stiffness through specialized mechanosensors, such as mechanosensitive ion channels or cell surface receptors including ...
Nivethitha Kota Lakshminaraasimulu   +3 more
wiley   +1 more source

APOE4 negates the effects of ovarian hormones on cerebrovascular endothelial and mitochondrial function

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend We examined the interaction effect of ovarian hormones and APOE genotype on cerebrovascular and mitochondrial function. Our data revealed that APOEε3 mice that were ovariectomized exhibited impaired endothelial function and greater oxidative stress and inflammation compared to sham controls.
Mackenzie N. Kehmeier   +9 more
wiley   +1 more source

Association between total and regional body fat measured by dual-energy X-ray absorptiometry and apolipoprotein B. [PDF]

open access: yesSci Rep
Chen C   +11 more
europepmc   +1 more source

National Trends and Disparities in Cancer Mortality Among Individuals With Alzheimer's Disease and Related Dementias in the United States, 1999–2020

open access: yesComputational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT As population aging accelerates, the coexistence of cancer and Alzheimer's disease and related dementias (ADRD) is becoming increasingly common. While each condition independently contributes to mortality, national trends in cancer‐related deaths occurring alongside ADRD—and their demographic and geographic disparities—remain poorly defined ...
Aasim Ali   +14 more
wiley   +1 more source

Applying Bayesian Multivariable Mendelian Randomisation to Prioritise Candidate Causal Traits From High‐Dimensional Data: Illustration From Estimation of the Effect of Maternal Metabolites on Offspring Birthweight

open access: yesGenetic Epidemiology, Volume 50, Issue 6, September 2026.
ABSTRACT Mendelian randomisation (MR) is an approach to causal inference that uses genetic variants to infer whether or not a causal effect exists, unbiased by unobserved confounding. MR estimation usually considers the effect of a single exposure on an outcome; it has recently been extended to explore potential effects of multiple exposures using ...
Ciarrah‐Jane Barry   +5 more
wiley   +1 more source

High‐density mutation tracks are associated with proton‐beam irradiation patterns in Sorghum bicolor

open access: yesThe Plant Genome, Volume 19, Issue 3, September 2026.
Abstract Induced mutagenesis is a cornerstone of crop functional genomics, yet the extent to which distinct radiation sources reshape the spatial distribution of mutations remains difficult to evaluate in reduced‐representation datasets. Here, we analyze a published genotyping‐by‐sequencing (GBS) panel (192,040 loci) to compare proton‐beam and gamma ...
Ezekiel Ahn   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy