Results 221 to 230 of about 19,002,199 (367)

Multi-functional role of apolipoprotein E in neurodegenerative diseases. [PDF]

open access: yesFront Aging Neurosci
Islam S   +4 more
europepmc   +1 more source

GREM1 deficiency induced bone marrow adipose niche promotes B‐cell acute lymphoblastic leukemia disease progression

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Too often, children treated for B‐cell acute lymphocytic leukemia (B‐ALL) experience relapse. Here, the authors investigate the role of dyslipidemia in leukemia progression. Higher adipogenicity in bone marrow mesenchymal stem cells, and increased triglyceride accumulation, are associated with higher risk of death.
Lili Song   +10 more
wiley   +1 more source

Sex‐specific associations of Roseburia with uric acid metabolism and hyperuricemia risk in females

open access: yesiMetaOmics, EarlyView.
Researchers recruited 623 participants, including 270 females, and used 16S rDNA sequencing to investigate gender differences in hyperuricemia. In healthy females, Roseburia was enriched, positively correlating with estrogen and negatively with uric acid, suggesting it is a potential biomarker affecting uric acid levels in females.
Zhihan Yang   +8 more
wiley   +1 more source

Characterization in vitro of interaction of human apolipoprotein E-free high density lipoprotein with human hepatocytes. [PDF]

open access: gold, 1990
Donald Schouten   +6 more
openalex   +1 more source

Pharmacokinetics and Safety of Fenofibrate in Participants with Mild Hepatic Impairment or with Advanced Fibrosis due to Metabolic‐Associated Fatty Liver Disease

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Fenofibrate is contraindicated in patients with advanced hepatic fibrosis due to limited clinical data. We evaluated the pharmacokinetics and safety of fenofibrate in participants with mild hepatic impairment (phase 1 study) or advanced fibrosis due to metabolic‐associated fatty liver disease (MAFLD; phase 2a study).
Islam R. Younis   +5 more
wiley   +1 more source

No effect of apolipoprotein E polymorphism on MRI brain activity during movie watching. [PDF]

open access: yesBrain Neurosci Adv
Raykov PP   +5 more
europepmc   +1 more source

Opposing effects of apolipoproteins E and C on lipoprotein binding to low density lipoprotein receptor-related protein.

open access: hybrid, 1990
Robert Kowal   +5 more
openalex   +1 more source

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