Results 21 to 30 of about 194,689 (341)

Reduced hippocampal volume in healthy young ApoE4 carriers: an MRI study. [PDF]

, 2012
The E4 allele of the ApoE gene has consistently been shown to be related to an increased risk of Alzheimer's disease (AD). The E4 allele is also associated with functional and structural grey matter (GM) changes in healthy young, middle-aged and older ...
Hampel, Harald, Lamberton, Franck, Matura, Silke, Miller, Julia, O'Dwyer, Laurence, Prvulovic, David, Rujescu, Dan, Scheibe, Monika, Tanner, Colby   +8 more
core   +7 more sources

Images in cardiovascular medicine : multiphoton microscopy for three-dimensional imaging of lymphocyte recruitment into apolipoprotein-E-deficient mouse carotid artery [PDF]

, 2007
Two recent elegant studies have shown that in apolipoprotein-E– deficient mice, the lamina adventitia is a major site of arterial wall inflammation associated with lymphocyte infiltration into atherosclerotic arteries and with formation of adventitial ...
Baker, Andrew H., Brewer, James M., Garside, Paul, Ialenti, Armando, Kennedy, Simon, Maffia, Pasquale, McInnes, Iain B., Zinselmeyer, Bernd H.   +7 more
core   +1 more source

The N-Terminus of Apolipoprotein A-V Adopts a Helix-Bundle Molecular Architecture [PDF]

, 2008
Previous studies of recombinant full-length human apolipoprotein A-V (apoA-V) provided evidence of the presence of two independently folded structural domains.
Beckstead, J. A., Guigard, E., Kay, C. M., Lee, D., Ryan, R. O., Weers, P. M.M., Wong, Kasuen   +6 more
core   +3 more sources

Evaluation of α-Synuclein and Apolipoprotein E as Potential Biomarkers in Cerebrospinal Fluid to Monitor Pharmacotherapeutic Efficacy in Dopamine Dictated Disease States of Parkinson’s Disease and Schizophrenia [Corrigendum]

Neuropsychiatric Disease and Treatment, 2022
Gupta AK, Pokhriyal R, Das U, et al. Neuropsychiatr Dis Treat. 2019;15:2073–2085. The authors wish to advise of typographical errors in Figures 1 and 2 and Table 3, the correct unit of apolipoprotein E concentration is μg/ml, and not pg/ml. Page
Gupta AK, Pokhriyal R, Das U, Khan MI, Ratna Kumar D, Gupta R, Chadda RK, Ramachandran R, Goyal V, Tripathi M, Hariprasad G   +10 more
doaj  

Human ApoD, an apolipoprotein up-regulated in neurodegenerative diseases, extends lifespan and increases stress resistance in Drosophila [PDF]

, 2008
Apolipoprotein D (ApoD) expression increases in several neurological disorders and in spinal cord injury. We provide a report of a physiological role for human ApoD (hApoD): Flies overexpressing hApoD are long-lived and protected against stress ...
Ahn, Boyles, Boyles, Butterfield, D. W. Walker, Desai, Do Carmo, Duffy, Guti  rrez, J. Muffat, Kalman, Lechner, Morais Cabral, Navarro, Oakley, Pfaffl, Provost, Provost, Rassart, S. Benzer, Sanchez, Sutcliffe, Terrisse, Thomas, Thomas, Toroser, Vogt, Walker, Wallace, Walsh, Weech   +30 more
core   +3 more sources

Role of Esrrg in the Fibrate-Mediated Regulation of Lipid Metabolism Genes in Human ApoA-I Transgenic Mice [PDF]

, 2009
We have used a new ApoA-I transgenic mouse model to identify by global gene expression profiling, candidate genes that affect lipid and lipoprotein metabolism in response to fenofibrate treatment.
A Chroni, A Duka, A Patsialou, A Rigotti, A Walsh, AP Feinberg, B Staels, B Staels, B Staels, B Staels, B Staels, B Staels, BN Finck, CW Miller, D Arsenijevic, D Lan, D Sanoudou, D Sanoudou, D Sanoudou, EM Rubin, ES Cathcart, F Yadetie, G Fredrikson, G Martin, H Duez, H Samyn, HB Rubins, HY Kan, J Karbowska, J Lin, J St Pierre, JC Fruchart, JD Brunzell, JJ Lehman, JK Reddy, JL Goldstein, JM Huss, JM Huss, JP Desager, K C Hayes, K Drosatos, K Motojima, K Schoonjans, K Schoonjans, KE Kypreos, KE Kypreos, KS Frederiksen, L Berthou, LA Pennacchio, LJ Kelly, M Bouly, MB Eisen, MC Hunt, MJ Holness, N Hennuyer, N Vu-Dac, N Vu-Dac, N Vu-Dac, N Vu-Dac, NF Cariello, P Puigserver, Q Guo, R Sladek, RB Vega, RL Jacobs, SA Greenberg, SN Schreiber, V Beisvag, V Giguere, V I Zannis, V Litvak, VG Tusher, VI Zannis, VI Zannis, VI Zannis, WC Roberts, X Prieur, Y Kamei, Y Nagai, Z Wu   +79 more
core   +3 more sources

Association of APOE gene polymorphism with stroke patients from rural Eastern India

Annals of Indian Academy of Neurology, 2020
Context: Studies from the different ethnic regions of the world have reported variable results on association of APOE gene polymorphism in stroke. Aim: The aim of this study is to find out the possible association of APOE polymorphism in stroke patients ...
Hilal Ahmad Ganaie, Arindam Biswas, Annada Prasad Bhattacharya, Sandip Pal, Jharna Ray, Shymal Kumar Das   +5 more
doaj   +1 more source

A well-characterised peak identification list of MALDI MS profile peaks for human blood serum [PDF]

, 2010
MALDI MS profiling, using easily available body fluids such as blood serum, has attracted considerable interest for its potential in clinical applications.
Anderson, Antwi, Bakun, Callesen, Fiedler, Harper, Hu, Koomen, Koomen, Liang, Marshall, Omenn, Orvisky, Pang, Peng, Schenk, Taguchi, Timms, Tirumalai, Villanueva, Villanueva, West-Norager, Zhang   +22 more
core   +1 more source

Study on the relationship between SLCO1B1 and ApoE gene polymorphisms and the risk of coronary heart disease in the Mongolian population

Clinical and Experimental Hypertension, 2021
Objective This study aimed to analyze the influence of SLCO1B1 and APOE gene polymorphisms on coronary heart disease in Mongolian population who living in Ordos area.
Rui-Bing Niu, Xiao-Xian Dong, Li-Ping Guo, Li Pan, Yue-Qin Hai, Xiao-Xiao Chen, Bao-Sheng Duan   +6 more
doaj   +1 more source

Apolipoprotein E Isoforms and AMD [PDF]

, 2015
The cholesterol transporting protein apolipoprotein E (ApoE) occurs in three allelic variants in humans unlike in other species. The resulting protein isoforms E2, E3 and E4 exhibit differences in lipid binding, integrating into lipoprotein particles and affinity for lipoprotein receptors. ApoE isoforms confer genetic risk for several diseases of aging
Toops, Kimberly A, Tan, Li Xuan, Lakkaraju, Aparna   +2 more
openaire   +5 more sources