Results 21 to 30 of about 334,081 (324)
Neuropsychiatric Disease and Treatment, 2022 Gupta AK, Pokhriyal R, Das U, et al. Neuropsychiatr Dis Treat. 2019;15:2073–2085. The authors wish to advise of typographical errors in Figures 1 and 2 and Table 3, the correct unit of apolipoprotein E concentration is μg/ml, and not pg/ml. Page
Gupta AK +10 more
doaj
Neural Regeneration Research, 2023 Alzheimer’s disease, the primary cause of dementia, is characterized by neuropathologies, such as amyloid plaques, synaptic and neuronal degeneration, and neurofibrillary tangles.
Beibei Wu +6 more
doaj +1 more source
Endothelial Cell-specific Loss of Breast Cancer Susceptibility Gene 2 Exacerbates Atherosclerosis [PDF]
arXiv, 2023 The BReast CAncer type 2 susceptibility protein (BRCA2) responds to DNA damage by participating in homology-directed repair. BRCA2 deficiency culminates in defective DNA damage repair (DDR) that when prolonged leads to the accumulation of DNA damage causing cancer or apoptosis.
arxiv
Apolipoprotein E Isoforms and AMD [PDF]
, 2015 The cholesterol transporting protein apolipoprotein E (ApoE) occurs in three allelic variants in humans unlike in other species. The resulting protein isoforms E2, E3 and E4 exhibit differences in lipid binding, integrating into lipoprotein particles and affinity for lipoprotein receptors. ApoE isoforms confer genetic risk for several diseases of aging
Toops, Kimberly A +2 more
openaire +4 more sources
Association of Apolipoprotein E gene polymorphism with Preeclampsia: a meta-analysis
Hypertension in Pregnancy, 2020 Objective The aim of this meta-analysis was to examine the association of ApoE polymorphism with the risk of developing PE. Methods A comprehensive search was carried out through PubMed, Scopus, and Embase.
Morteza Abyadeh +4 more
doaj +1 more source
Кардиоваскулярная терапия и профилактика, 2020 Aim. To analyze the associations of apolipoprotein E (APOE) gene polymorphisms (rs7412 and rs4420638) with the risk of coronary artery disease (CAD) and the effectiveness of lipid-lowering therapy with rosuvastatin.Material and methods.
M. I. Churilin +12 more
doaj +1 more source
Apolipoprotein E Gene Polymorphism And Its Effect On Plasma Lipids In Arteriosclerosis [PDF]
Journal of Clinical and Diagnostic Research, 2013 Background & Objectives: Myocardial infarction and stroke are leading causes of death worldwide. Primarily, arteriosclerosis is responsible for these events. There is a strong family history suggesting a genetic cause.
P. D. Zende +3 more
doaj +1 more source
Protein corona critically affects the bio-behaviors of SARS-CoV-2 [PDF]
arXiv, 2021 The outbreak of the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has become a worldwide public health crisis. When the SARS-CoV-2 enters the biological fluids in the human body, different types of biomolecules (in particular proteins) may adsorb on its surface and alter its infection ability.
arxiv
Терапевтический архив, 2023 This study is aimed at investigating epileptic seizures, one of the consequences of traumatic brain injury (TBI). Immediate and early post-traumatic seizures, as well as late post-traumatic epileptic seizures or post-traumatic epilepsy, can have ...
Kseniia K. Kriukova +10 more
doaj +1 more source
Unresolved excess accumulation of myelin-derived cholesterol contributes to scar formation after spinal cord injury [PDF]
arXiv, 2022 Background: Spinal cord injury triggers complex pathological cascades, resulting in destructive tissue damage and incomplete tissue repair. Scar formation is generally considered as a barrier for regeneration in central nervous system (CNS), while the intrinsic mechanism of scar-forming after spinal cord injury has not been completed deciphered ...
arxiv