Results 211 to 220 of about 37,488 (288)

Novel Insights into Causal Effects of Serum Lipids and Apolipoproteins on Cardiovascular Morpho-Functional Phenotypes. [PDF]

Cardiovasc Toxicol
Liu A, Liu X, Wei Y, Xiang X, Chen Y, Zheng Z, Xu C, Yang S, Zhao K.   +8 more
europepmc   +1 more source

Microglia Single‐Cell RNA‐Seq Enables Robust and Applicable Markers of Biological Aging

Aging Cell, EarlyView.
This study develops computational approaches to translate single‐cell based transcriptomic signatures of microglia into aging clocks, or machine learning models of age. These models can be broadly applied to new single‐cell or bulk RNA‐sequencing datasets to gain novel biological insights and evaluate how environmental inputs (such as stress) affect ...
Natalie Stanley, Luvna Dhawka, Sneha Jaikumar, Yu‐Chen Huang, Anthony S. Zannas   +4 more
wiley   +1 more source

Deciphering Acute Coronary Syndromes Pathobiology Through Proteomics. [PDF]

J Cardiovasc Dev Dis
Nieddu G, Formato M, Lepedda AJ.
europepmc   +1 more source

A Comprehensive Multiomics Signature of Doxorubicin‐Induced Cellular Senescence in the Postmenopausal Human Ovary

Aging Cell, EarlyView.
Explants of human postmenopausal ovarian cortex and medulla were treated with doxorubicin for 24 h followed by culture for up to 10 days in doxorubicin‐free medium. Single nuclei sequencing and proteomics revealed an unbiased signature of ovarian senescence driven by epithelial cells in the cortex and stromal cells in the cortex and medulla ...
Pooja Raj Devrukhkar, Mark A. Watson, Bikem Soygur, Fei Wu, Joanna Bons, Hannah Anvari, Tomiris Atazhanova, Nicolas Martin, Tommy Tran, Kevin Schneider, Jacob P. Rose, Daniel Winer, Elisheva Shanes, Mary Ellen G. Pavone, Judith Campisi, David Furman, Simon Melov, Birgit Schilling, Francesca E. Duncan   +18 more
wiley   +1 more source

Low apolipoprotein A-II levels causally contribute to increased mortality in septic shock. [PDF]

J Intensive Care
Takahashi N, Campbell KR, Shimada T, Nakada TA, Russell JA, Walley KR.   +5 more
europepmc   +1 more source

Long‐term alcohol consumption and incident health risk conditions related to cardiometabolic risk markers: A 20‐year prospective cohort study

Addiction, EarlyView.
Abstract Background and aims Amid questions about a perceived association between low‐to‐moderate alcohol consumption and reduced cardiovascular risk from recent studies, research examining the impact of alcohol consumption on cardiometabolic risk markers has reported inconsistent results.
Sooyeun Choi, Taeyoung Park, Youjin Je
wiley   +1 more source

Assessment of lipid profile and its association with acne vulgaris severity in adolescents and young adults: A cross-sectional study in Kurdistan Region, Iraq. [PDF]

Qatar Med J
Abdulsattar Mosa A, Ahmad Hamza M, Yaseen Khalaf M.   +2 more
europepmc   +1 more source

Genetic Determinants of the Familial Hypercholesterolaemia Phenotype

Annals of Human Genetics, EarlyView.
ABSTRACT Individuals with familial hypercholesterolaemia (FH) have severely elevated plasma concentrations of low‐density lipoprotein cholesterol (LDL‐C) from birth and as a consequence have an elevated morbidity and mortality due to the development of coronary heart disease (CHD).
Steve Eric Humphries, Marta Futema
wiley   +1 more source

Association between Apolipoprotein B and diabetic nephropathy: insights from the National Health and Nutrition Examination Survey 2007-2016 and Mendelian randomization analysis. [PDF]

Nutr Diabetes
Wang H, Wu S, Pan D, Ning Y, Fu Y, Feng C, Guo J, Liu Z, Gu Y.   +8 more
europepmc   +1 more source