Results 91 to 100 of about 26,023 (245)

A protective role for N-acylphosphatidylethanolamine phospholipase D in 6-OHDA-induced neurodegeneration. [PDF]

, 2019
N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) catalyzes the cleavage of membrane NAPEs into bioactive fatty-acid ethanolamides (FAEs). Along with this precursor role, NAPEs might also serve autonomous signaling functions. Here, we report that
Palese, Francesca, Piomelli, Daniele, Pontis, Silvia, Realini, Natalia   +3 more
core  

Slow oscillatory activity and levodopa-induced dyskinesias in Parkinson’s disease [PDF]

, 2006
The pathophysiology of levodopa-induced dyskinesias (LID) in Parkinson’s disease is not well understood. We have recorded local field potentials (LFP) from macroelectrodes implanted in the subthalamic nucleus (STN) of 14 patients with Parkinson’s ...
Alegre-Esteban, M. (Manuel), Alonso-Frech, F. (F.), Artieda, J. (Julio), Guridi-Legarra, J. (Jorge), Manrique, M. (Miguel), Obeso, J.A. (José A.), Rodriguez-Oroz, M.C. (María Cruz), Valencia-Ustarroz, M. (Miguel), Zamarbide, I. (I.)   +8 more
core   +1 more source

A Systematic Review of the Parkinson's Foundation Hospital Care Recommendations

Movement Disorders Clinical Practice, Volume 13, Issue 1, Page 29-43, January 2026.
Abstract Background People with Parkinson's disease (PwP) face increased risks of complications and longer hospital stays compared to the general population. Four major factors contribute to increased morbidity and mortality during hospitalization: medication timing errors, administration of harmful medications, restricted mobility, and dysphagia ...
Ariane Veilleux Carpentier, Irene A. Malaty, Peter A. LeWitt, Hooman Azmi, Anne Brooks, Edward Pollak, Ellen L. Air, Heather Simpson, Jaime Thomas, Florian P. Thomas, Lisa Cocoziello, Sheera Rosenfeld, Michael S. Okun   +12 more
wiley   +1 more source

Evaluation of D1 and D2 dopamine receptors families’ role in basolateral amygdala on working and reference memory

یافته‌های نوین در علوم زیستی, 2018
The Basolateral Amygdala (BLA) has modulatory effects on working and reference memory. The aim of this study was the evaluation of effects of dopaminergic system in the BLA of rats on working and reference memory behaviors.
Farhad Valizadegan, Maryam Rahimi Tesyie
doaj  

Treating Disorders of Consciousness With Apomorphine: Protocol for a Double-Blind Randomized Controlled Trial Using Multimodal Assessments

Frontiers in Neurology, 2019
Background: There are few available therapeutic options to promote recovery among patients with chronic disorders of consciousness (DOC). Among pharmacological treatments, apomorphine, a dopamine agonist, has exhibited promising behavioral effects and ...
Leandro R. D. Sanz, Leandro R. D. Sanz, Nicolas Lejeune, Nicolas Lejeune, Nicolas Lejeune, Nicolas Lejeune, Séverine Blandiaux, Séverine Blandiaux, Estelle Bonin, Estelle Bonin, Aurore Thibaut, Aurore Thibaut, Aurore Thibaut, Aurore Thibaut, Johan Stender, Neal M. Farber, Ross D. Zafonte, Ross D. Zafonte, Nicholas D. Schiff, Steven Laureys, Steven Laureys, Olivia Gosseries, Olivia Gosseries   +22 more
doaj   +1 more source

Efficacy and Safety of IncobotulinumtoxinA for Treatment of Sialorrhea: A Multicenter, Phase 3 Study in Japan

Movement Disorders Clinical Practice, Volume 13, Issue 1, Page 120-130, January 2026.
This study demonstrated significant treatment efficacy and safety of incobotulinumtoxinA injection in Japanese patients with chronic sialorrhea caused by Parkinson's disease and other neurological conditions. Suppression of salivary secretion and improvement in drooling symptoms were also observed throughout 48 weeks.
Nobutaka Hattori, Yohei Mukai, Noriko Nishikawa, Kazuko Hasegawa, Masahiko Tomiyama, Yasuyoshi Kimura, Yoshio Tsuboi, Ryosuke Takahashi, Ryota Nakamura, Yuishin Izumi, Hirohisa Watanabe, Morinobu Seki, Kenji Sekiguchi, Shohei Tateishi, Yusaku Matsushita, Yusaku Nakamura   +15 more
wiley   +1 more source

Synthetic aporphine alkaloids are potential therapeutics for Leigh syndrome

Scientific Reports
Mitochondrial diseases are mainly caused by dysfunction of mitochondrial respiratory chain complexes and have a variety of genetic variants or phenotypes. There are only a few approved treatments, and fundamental therapies are yet to be developed.
Mizuki Kobayashi, Akihiko Miyauchi, Eriko F. Jimbo, Natsumi Oishi, Shiho Aoki, Miyuki Watanabe, Yasushi Yoshikawa, Yutaka Akiyama, Takanori Yamagata, Hitoshi Osaka   +9 more
doaj   +1 more source

Design of an Optical Probe to Monitor Vaginal Hemodynamics during Sexual Arousal

Sensors, 2019
An optical probe was developed to measure the change of oxy-hemoglobin (OHb), deoxy- hemoglobin (RHb), and total hemoglobin (THb) along with temperature from the vaginal wall of female rats.
Hyeryun Jeong, Myeongsu Seong, Hyun-Suk Lee, Kwangsung Park, Sucbei Moon, Jae Gwan Kim   +5 more
doaj   +1 more source

Subtype of the Freezing of Gait and Motor Function in Patients with Parkinson's Disease

Movement Disorders Clinical Practice, Volume 13, Issue 1, Page 90-97, January 2026.
Abstract Background The association between freezing of gait and motor function in Parkinson's disease is variable, and the results suggest the existence of subtypes. Objectives This study aimed to identify the subtypes of freezing of gait and motor function in patients with Parkinson's disease. Methods Sixty‐one patients were included.
Katsuya Sakai, Tsubasa Kawasaki, Kichol Kim, Jyunya Ogawa, Yuya Yamaguchi   +4 more
wiley   +1 more source

Examining Device Usage Patterns in Outpatient Telemedicine Video Visits among Movement Disorders Patients

Movement Disorders Clinical Practice, Volume 13, Issue 1, Page 243-247, January 2026.
Abstract Background Telemedicine has improved access to care, yet device usage for virtual visits remains underexplored. Objective To characterize device usage patterns for video televisits across sociodemographic factors in a tertiary Movement Disorders clinic in the United States.
Mitra Afshari, Vijay G. Palakuzhy, Bichun Ouyang, Glenn T. Stebbins, Christopher G. Goetz   +4 more
wiley   +1 more source