Results 11 to 20 of about 13,147 (207)
Continuous subcutaneous apomorphine monotherapy in Parkinson’s disease [PDF]
Annals of Agricultural and Environmental Medicine, 2019 Introduction and objective Continuous subcutaneous apomorphine (APO) treatment is one of the 3 therapeutic options for advanced Parkinson’s disease (PD), in addition to deep brain stimulation (DBS) and intrajejunal levodopa.
Ewa Papuć +2 more
doaj +2 more sources
Stability of apomorphine in solutions containing selected antioxidant agents [PDF]
Drug Design, Development and Therapy, 2016 Zen Yang Ang, Michael Boddy, Yandi Liu, Bruce Sunderland School of Pharmacy, Faculty of Health Sciences, Curtin University, Bentley, WA, Australia Abstract: Apomorphine in solution undergoes rapid autoxidation, producing greenish colored solutions ...
Ang ZY, Boddy M, Liu Y, Sunderland B
doaj +3 more sources
Genotoxic, neurotoxic and neuroprotective activities of apomorphine and its oxidized derivative 8-oxo-apomorphine [PDF]
Brazilian Journal of Medical and Biological Research, 2005 Apomorphine is a dopamine receptor agonist proposed to be a neuroprotective agent in the treatment of patients with Parkinson's disease. Both in vivo and in vitro studies have shown that apomorphine displays both antioxidant and pro-oxidant actions, and ...
J.N. Picada +2 more
doaj +5 more sources
Clinical trial evaluating apomorphine oromucosal solution in Parkinson's disease patients [PDF]
Clinical and Translational ScienceApomorphine, used to treat OFF episodes in patients with Parkinson's disease (PD), is typically administered via subcutaneous injections. Administration of an oromucosal solution could offer a non‐invasive and user‐friendly alternative.
Eva Thijssen +8 more
doaj +2 more sources
Apomorphine effects on the hippocampus [PDF]
Neural Regeneration Research, 2018 Apomorphine is a non-specific dopamine receptor agonist that has been used in the treatment of some diseases and mental disorders. Its use has particularly well documented in Parkinson's disease (PD).
Luis Enrique Arroyo-Garcia +2 more
doaj +3 more sources
Turmeric active substance, curcumin, enhanced apomorphine-induced yawning in rats [PDF]
Avicenna Journal of Phytomedicine, 2013 Objective: Curcumin is a major constituent of turmeric and influences many functions of the brain. In the present study, we investigated the effect of curcumin on yawning induced by apomorphine in rats.
Esmaeal Tamaddonfard
doaj +2 more sources
Au nanoparticle-based sensor for apomorphine detection in plasma [PDF]
Beilstein Journal of Nanotechnology, 2015 Artificially roughened gold surfaces with controlled nanostructure produced by pulsed laser deposition have been investigated as sensors for apomorphine detection aiming at clinical application.
Chiara Zanchi +6 more
doaj +2 more sources
Intermittent Subcutaneous Injections of Apomorphine in Parkinson’s Disease [PDF]
, 2022 The intermittent subcutaneous injection of apomorphine is highly effective in the management of motor and non-motor symptoms of Parkinson's disease. Although it has been shown that apomorphine injection can be safely used in selected cases at all stages ...
Nazli Durmaz Celik +12 more
core +1 more source
Motor Evoked Potentials Improve Targeting in Deep Brain Stimulation Surgery
Neuromodulation: Technology at the Neural Interface, EarlyView., 2021 Abstract Objectives One of the main challenges posed by the surgical deep brain stimulation (DBS) procedure is the successful targeting of the structures of interest and avoidance of side effects, especially in asleep surgery. Here, intraoperative motor evoked potentials (MEPs) might serve as tool to identify the pyramidal tract.
Petyo Nikolov +7 more
wiley +1 more source
Apomorphine in the Treatment of Parkinson's Disease [PDF]
, 2021 Apomorphine is a dopamine agonist used in the treatment of some motor and non-motor complications during Parkinson's disease, which could be administered as an intermittent or continuous infusion.
ÖZKAYNAK, SEHÜR SİBEL +7 more
core +1 more source