Results 21 to 30 of about 21,736 (211)
Challenges and trends in apomorphine drug delivery systems for the treatment of Parkinson's disease
Parkinson's disease (PD) is a chronic debilitating disease affecting approximately 1% of the population over the age of 60. The severity of PD is correlated to the degree of dopaminergic neuronal loss.
Nrupa Borkar, Huiling Mu, René Holm
doaj +1 more source
On the Behavior of the Respiratory Muscles During Vomiting [PDF]
In order to produce vomiting in the dogs decerebrated and unanesthetized, apomorphine or copper sulfate was administered. The behaviors of both the inspiratory and the expiratory muscles were studied through the course of the act of vomiting by the ...
Hukuhara, Takesi +2 more
core +1 more source
MCH and apomorphine in combination enhance action potential firing of nucleus accumbens shell neurons in vitro [PDF]
The MCH and dopamine receptor systems have been shown to modulate a number of behaviors related to reward processing, addiction, and neuropsychiatric conditions such as schizophrenia and depression. In addition, MCH and dopamine receptors can interact in
F Woodward Hopf +3 more
doaj +2 more sources
Background: Impulsive compulsive behaviors (ICBs) can affect a significant number of Parkinson’s disease (PD) patients. Objective: We have studied brain samples from a brain bank of PD patients who received apomorphine via continuous infusion in life to
Pedro Barbosa +3 more
doaj +1 more source
The Influence of Hyperactivity of the Hypothalamic-pituitary-adrenal Axis and Hyperglycemia on the 5-HT2A Receptor-mediated Wet-dog Shake Responses in Rats [PDF]
Hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis induces hyperglycemia and serotonin (5-HT)2A receptor supersensitivity. In the present study, to investigate the effect of hyperglycemia on the function of 5-HT2A receptors, we compared the 5-
Amano, Manabu +7 more
core +1 more source
Costs of Parkinson's Disease and Antiparkinsonian Pharmacotherapy: An Italian Cohort Study [PDF]
Objective: Antiparkinsonian pharmacotherapy is costly and the determinants of drug costs in Parkinson's disease (PD) have been poorly investigated. The objective of this study was to investigate the costs of PD and antiparkinsonian drugs in an Italian ...
Balzer-Geldsetzer, Monika +10 more
core +1 more source
Apomorphine: The initial indian experience in relation to response tests and pumps
Background: Apomorphine is an option for continuous dopaminergic therapy in Parkinson's disease (PD). However, its effects in varied populations are limited due to its availability.
L K Prashanth +3 more
doaj +1 more source
Apomorphine Targets the Pleiotropic Bacterial Regulator Hfq
Hfq is a bacterial regulator with key roles in gene expression. The protein notably regulates translation efficiency and RNA decay in Gram-negative bacteria, thanks to its binding to small regulatory noncoding RNAs. This property is of primary importance
Florian Turbant +6 more
doaj +1 more source

