Erectile dysfunction - an update of current practice and future strategies [PDF]
, 2013 Erectile dysfunction (ED) is defined as the inability to achieve and maintain a penile erection adequate for satisfactory sexual intercourse.1 Up to 150 million men worldwide suffer from ED and this figure is likely to double by the year 2025.2 A number
Kalsi, J, Muneer, A
core +1 more source
Subcutaneous Apomorphine Infusion Initiation Is Associated with Impulse Control Disorder Attenuation in Advanced Parkinson's Disease Patients: Insights from the French NS-Park Cohort. [PDF]
Mov Disord Clin PractAbstract Background Impulse control disorders (ICD) are common non‐motor complications in Parkinson's disease (PD), particularly in patients receiving oral dopamine agonists (DA). Continuous subcutaneous apomorphine infusion (CSAI) is a device‐aided therapy for advanced PD, but its effects on ICD remain underexplored in real‐world settings.
Desjardins C +20 more
europepmc +2 more sources
Apomorphine in the Treatment of Parkinson’s Disease
Türk Nöroloji Dergisi, 2021 Apomorphine is a dopamine agonist used in the treatment of some motor and non-motor complications during Parkinson’s disease, which could be administered as an intermittent or continuous infusion.
Serhat Özkan
doaj +1 more source
On the Behavior of the Respiratory Muscles During Vomiting [PDF]
, 1957 In order to produce vomiting in the dogs decerebrated and unanesthetized, apomorphine or copper sulfate was administered. The behaviors of both the inspiratory and the expiratory muscles were studied through the course of the act of vomiting by the ...
Hukuhara, Takesi +2 more
core +1 more source
Apomorphine Targets the Pleiotropic Bacterial Regulator Hfq
Antibiotics, 2021 Hfq is a bacterial regulator with key roles in gene expression. The protein notably regulates translation efficiency and RNA decay in Gram-negative bacteria, thanks to its binding to small regulatory noncoding RNAs. This property is of primary importance
Florian Turbant +6 more
doaj +1 more source
Catecholamine-Based Treatment in AD Patients: Expectations and Delusions. [PDF]
, 2015 In Alzheimer disease, the gap between excellence of diagnostics and efficacy of therapy is wide. Despite sophisticated imaging and biochemical markers, the efficacy of available therapeutic options is limited.
Alessandro eStefani +9 more
core +3 more sources
Myopes have significantly higher serum melatonin concentrations than non-myopes [PDF]
, 2017 Purpose Experimental animal models of myopia demonstrate that higher melatonin (Mel) and lower dopamine (DA) concentrations actively promote axial elongation.
Ackermann +70 more
core +2 more sources
Transplantation of melanocytes obtained from the skin ameliorates apomorphine-induced abnormal behavior in rodent hemi-parkinsonian models [PDF]
, 2013 Tyrosinase, which catalyzes both the hydroxylation of tyrosine and consequent oxidation of L-DOPA to form melanin in melanocytes, is also expressed in the brain, and oxidizes L-DOPA and dopamine.
Asanuma, Masato +5 more
core +7 more sources
Serotonin system implication in L-DOPA-induced dyskinesia: from animal models to clinical investigations [PDF]
, 2014 In the recent years, the serotonin system has emerged as a key player in the induction of l-DOPA-induced dyskinesia (LID) in animal models of Parkinson's disease. In fact, serotonin neurons possess the enzymatic machinery able to convert exogenous l-DOPA
CARTA, MANOLO, TRONCI, ELISABETTA
core +1 more source
Turmeric active substance, curcumin, enhanced apomorphine-induced yawning in rats [PDF]
Avicenna Journal of Phytomedicine, 2013 Objective: Curcumin is a major constituent of turmeric and influences many functions of the brain. In the present study, we investigated the effect of curcumin on yawning induced by apomorphine in rats.
Esmaeal Tamaddonfard
doaj