Results 41 to 50 of about 35,166 (278)
Apomorphine Targets the Pleiotropic Bacterial Regulator Hfq
Hfq is a bacterial regulator with key roles in gene expression. The protein notably regulates translation efficiency and RNA decay in Gram-negative bacteria, thanks to its binding to small regulatory noncoding RNAs. This property is of primary importance
Florian Turbant+6 more
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Apomorphin in Eclampsia. [PDF]
Hartshorn, Okla., May 4, 1908. To the Editor: —Dr. Morgan, in his article on "Treatment of Eclampsia" inThe Journal, May 2, 1908, makes no mention of apomorphin in that condition, and I do not remember ever having seen this drug mentioned in this connection.
openaire +2 more sources
Apomorphine Subcutaneous Injection for the Management of Morning Akinesia in Parkinson's Disease
In patients with motor fluctuations complicating Parkinson's disease (PD), delays in time‐to‐ON with levodopa are common. This open‐label study aimed to assess the effect of apomorphine on time‐to‐ON in PD patients with morning akinesia.
S. Isaacson+5 more
semanticscholar +1 more source
Reactionen Des Apomorphins [PDF]
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Quehl,, K�hler, H.
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Continuous subcutaneous apomorphine monotherapy in Parkinson’s disease
Introduction and objective Continuous subcutaneous apomorphine (APO) treatment is one of the 3 therapeutic options for advanced Parkinson’s disease (PD), in addition to deep brain stimulation (DBS) and intrajejunal levodopa.
Ewa Papuć+2 more
doaj +1 more source
Dopamine Autoreceptor Regulation of a Hypothalamic Dopaminergic Network [PDF]
Acknowledgments The authors thank Drs. Gilberto Fisone, Jessica Ausborn, Abdel El Manira, Gilad Silberberg, and members of the C.B. laboratory for advice, as well as Paul Williams for expert help with the graphical abstract. This study was supported by a
Broberger, Christian+3 more
core +3 more sources
We have recently reported G-protein coupled receptor (GPCR) model structures for the active and inactive states of the human dopamine D2 receptor (D2R) using adrenergic crystal structures as templates.
S. Durdağı+4 more
semanticscholar +1 more source
Apomorphine: A potential modifier of amyloid deposition in Parkinson's disease?
Evidence from clinical and pathological studies suggests a role for both alpha‐synuclein and amyloid‐beta in the pathophysiology of dementia associated with PD.
A. Yarnall+8 more
semanticscholar +1 more source
Turmeric active substance, curcumin, enhanced apomorphine-induced yawning in rats [PDF]
Objective: Curcumin is a major constituent of turmeric and influences many functions of the brain. In the present study, we investigated the effect of curcumin on yawning induced by apomorphine in rats.
Esmaeal Tamaddonfard
doaj
Parkinson’s disease (PD) is a common neurodegenerative disease. At present, 5–10% of PD patients are found to have monogenic form of the disease. Each genetic mutation has its own unique clinical features and disease trajectory.
Germaine Hiu-Fai Chan
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