Results 51 to 60 of about 14,827 (208)
Background: Apomorphine infusion therapy remains under-used and there are no comparative studies of motor and non-motor effects of apomorphine infusion.
Pablo Martinez-Martin +11 more
doaj +1 more source
Challenges of Pain in Parkinson's Disease: Results from the OCEAN Study
Abstract Background Pain is a common non‐motor symptom in Parkinson’s disease (PD) and is often associated to fluctuations. Objective The OpiCapone Effect on motor fluctuations and pAiN (OCEAN) study evaluated the effect of opicapone on fluctuation‐related pain when added to levodopa therapy in PD patients.
Kallol Ray Chaudhuri +13 more
wiley +1 more source
The octadecaneuropeptide ODN inhibits apomorphine-induced yawning in rats
International audienceHigh concentrations of diazepam-binding inhibitor (DBI) have been detected in brain areas containing dopaminergic cell bodies and nerve terminals.
Garcia de Mateos-Verchere, Juanita +9 more
core +1 more source
Apathy in Lewy Body Disorders: A Position Paper
Abstract Apathy is one of the most prevalent and disabling non‐motor symptoms in Parkinson's disease (PD) and dementia with Lewy bodies (DLB), collectively referred to as Lewy body disorders (LBDs). It is associated with reduced quality of life, accelerated cognitive decline, increased caregiver burden, and poorer functional outcomes, yet remains ...
Jaime Kulisevsky +12 more
wiley +1 more source
The effect of the dopamine agonist, apomorphine, on regional cerebral blood flow in normal volunteers. [PDF]
Apomorphine, a non-selective dopamine agonist, has been used as a pharmacological probe for investigating central dopaminergic neurotransmission in psychiatric illness.
Friston, K. +7 more
core
Short-latency somatosensory evoked potentials (SSEPs) were recorded from 10 parkinsonian patients in ‘off’ and ‘on’ states induced by apomorphine and levodopa.
M. Miranda, J. L. Castillo, F. Araya
doaj +1 more source
The Costs of Parkinson's Disease in Europe: Results of the Costs of Illness in Neurology Initiative
Abstract Background Parkinson's disease (PD) is the second most common neurodegenerative disease. It imposes substantial and growing burden on patients, families, and caregivers and reduces quality of life. The disability and care needs associated with PD carry economic ramifications.
Luisa Welter +15 more
wiley +1 more source
Apomorphine Is a Bimodal Modulator of TRPA1 Channels [PDF]
Apomorphine is a non-narcotic derivative of morphine, which acts as a dopamine agonist and is clinically used to treat "offstates" in patients suffering from Parkinson's disease.
Nicole Urban +4 more
core
Au nanoparticle-based sensor for apomorphine detection in plasma
Artificially roughened gold surfaces with controlled nanostructure produced by pulsed laser deposition have been investigated as sensors for apomorphine detection aiming at clinical application.
Chiara Zanchi +6 more
doaj +1 more source
Background The hydro-ethanolic whole plant extract of Synedrella nodiflora (SNE) has demonstrated anticonvulsant, sedative and analgesic effects. Preliminary studies conducted in animals, SNE significantly decreased stereotypic behaviours suggesting ...
Patrick Amoateng +6 more
doaj +1 more source

