Results 61 to 70 of about 13,147 (207)

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor   +4 more
wiley   +1 more source

Toll‐like receptor 4 mediates lipopolysaccharide‐induced emesis

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 16, Page 4592-4609, August 2026.
Background and Purpose Lipopolysaccharide (LPS) induces inflammation and sepsis through Toll‐like receptor 4 (TLR4) activation. Common laboratory animals do not exhibit emesis, but administration of LPS in piglets, cats, and dogs induces emesis via peripheral mechanisms.
Luping Liu   +5 more
wiley   +1 more source

Chronic Subcutaneous Infusion Therapy with Apomorphine in Advanced Parkinson's Disease Compared to Conventional Therapy: A Real Life Study of Non Motor Effect

open access: yesJournal of Parkinson’s Disease, 2011
Background: Apomorphine infusion therapy remains under-used and there are no comparative studies of motor and non-motor effects of apomorphine infusion.
Pablo Martinez-Martin   +11 more
doaj   +1 more source

Effects of Repeated Apomorphine and Haloperidol Treatments on Subsequent Behavioral Sensitivity to Apomorphine [PDF]

open access: yes, 1989
Effects of repeated apomorphine and haloperidol treatments on subsequent behavioral sensitivity to apomorphine. PHARMACOL BIOCHEM BEHAV 34(2) 345-347, 1989.- In a 2 × 2 factorial design, four groups of rats (n = l0 each) were injected daily with ...
Rowlett, James K., Mattingly, Bruce A.
core  

Severe Lower Limb and Abdominal Edema Associated with Subcutaneous Apomorphine Infusion

open access: yes
Movement Disorders Clinical Practice, EarlyView.
Guillaume Costentin, David Maltête
wiley   +1 more source

ZDHHC9‐Mediated Palmitoylation of ACSL4 Drives Ferroptosis in Diabetes Mellitus–Induced Erectile Dysfunction

open access: yesAdvanced Science, Volume 13, Issue 42, 28 July 2026.
ABSTRACT Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.
Wanyang Guo   +14 more
wiley   +1 more source

Somatosensory Evoked Potentials and Dopaminergic Responsiveness to Apomorphine and Levodopa in Parkinsonian Patients

open access: yesBehavioural Neurology, 1996
Short-latency somatosensory evoked potentials (SSEPs) were recorded from 10 parkinsonian patients in ‘off’ and ‘on’ states induced by apomorphine and levodopa.
M. Miranda, J. L. Castillo, F. Araya
doaj   +1 more source

Extract of Synedrella nodiflora (L) Gaertn exhibits antipsychotic properties in murine models of psychosis

open access: yesBMC Complementary and Alternative Medicine, 2017
Background The hydro-ethanolic whole plant extract of Synedrella nodiflora (SNE) has demonstrated anticonvulsant, sedative and analgesic effects. Preliminary studies conducted in animals, SNE significantly decreased stereotypic behaviours suggesting ...
Patrick Amoateng   +6 more
doaj   +1 more source

Mechanisms of apomorphine cytotoxicity towards rat glioma C6 cells: protection by bovine serum albumin and formation of apomorphine-protein conjugates [PDF]

open access: yes, 1999
Apomorphine cytotoxicity towards rat glioma C6 cells was recently demonstrated to be time- and concentration-dependent. In the present work, the mechanism of cytotoxicity of apomorphine was further studied in the C6 cell line. We showed that bovine serum
Netter, Patrick   +2 more
core  

Apomorphine infusion in advanced Parkinson disease [PDF]

open access: yes, 2018
The TOLEDO study provides new evidence to support the use of subcutaneous apomorphine infusion to control motor fluctuations in patients with advanced Parkinson disease.
Peter Jenner   +3 more
core   +1 more source

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