Results 61 to 70 of about 21,736 (211)

Continuous Subcutaneous Versus Intestinal Levodopa Infusion for Parkinson's Disease: A Real‐World, Monocentric, Observational Study and Critical Review

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Subcutaneous foslevodopa‐foscarbidopa (SCFF) is a novel, non‐surgical dopaminergic infusion therapy for better controlling motor fluctuations in advanced Parkinson's disease (PD). However, there are scarce real‐world data on efficacy, adverse events and comparisons with other infusion strategies. Objectives Here, we aimed to provide
Johannes Hartig   +6 more
wiley   +1 more source

Chronic Subcutaneous Infusion Therapy with Apomorphine in Advanced Parkinson's Disease Compared to Conventional Therapy: A Real Life Study of Non Motor Effect

open access: yesJournal of Parkinson’s Disease, 2011
Background: Apomorphine infusion therapy remains under-used and there are no comparative studies of motor and non-motor effects of apomorphine infusion.
Pablo Martinez-Martin   +11 more
doaj   +1 more source

Sleep loss and recovery after administration of drugs related to different arousal systems in rats [PDF]

open access: yes, 2016
Sleep is homeostatically regulated suggesting a restorative function. Sleep deprivation is compensated by an increase in length and intensity of sleep.
Détári, L   +4 more
core   +1 more source

Risk‐Benefit Considerations in Deep Brain Stimulation Discontinuation for Late‐Stage Parkinson's Disease

open access: yesMovement Disorders Clinical Practice, EarlyView.
ABSTRACT Background Management of deep brain stimulation (DBS) in late‐stage Parkinson's disease (LSPD) remains challenging, particularly when deciding whether to continue or discontinue stimulation, and evidence on risk–benefit considerations is limited. Objectives To identify key factors to improve decision‐making in DBS management for LSPD patients.
Pietro Antenucci   +9 more
wiley   +1 more source

The effects of Nicotine on licking behavior induced by Apomorphine in rats

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 1999
Objective: The purpose of the present study was to determine the possible interaction of nicotine or muscarinic receptor mechanism(s) with the licking behavior induced by apomorphine in rats.
MR Zarrindast, M Shecharchi, M Rezayat
doaj  

Endogenous Dopamine and Endocannabinoid Signaling Mediate Cocaine-Induced Reversal of AMPAR Synaptic Potentiation in the Nucleus Accumbens Shell [PDF]

open access: yes, 2018
Repeated exposure to drugs of abuse alters the structure and function of neural circuits mediating reward, generating maladaptive plasticity in circuits critical for motivated behavior.
Hearing, Matthew   +3 more
core   +2 more sources

Continuous Apomorphine Infusion in Multiple System Atrophy Real‐World Insights From a French Nationwide Retrospective Cohort

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Continuous subcutaneous apomorphine infusion (CSAI) is effective in Parkinson's disease but has not been evaluated in multiple system atrophy (MSA). Objective To assess the 6‐month efficacy and tolerability of CSAI in MSA patients. Methods French multicenter retrospective registry‐based analysis of CSAI use in MSA.
Simon Lamy   +16 more
wiley   +1 more source

Somatosensory Evoked Potentials and Dopaminergic Responsiveness to Apomorphine and Levodopa in Parkinsonian Patients

open access: yesBehavioural Neurology, 1996
Short-latency somatosensory evoked potentials (SSEPs) were recorded from 10 parkinsonian patients in ‘off’ and ‘on’ states induced by apomorphine and levodopa.
M. Miranda, J. L. Castillo, F. Araya
doaj   +1 more source

Extract of Synedrella nodiflora (L) Gaertn exhibits antipsychotic properties in murine models of psychosis

open access: yesBMC Complementary and Alternative Medicine, 2017
Background The hydro-ethanolic whole plant extract of Synedrella nodiflora (SNE) has demonstrated anticonvulsant, sedative and analgesic effects. Preliminary studies conducted in animals, SNE significantly decreased stereotypic behaviours suggesting ...
Patrick Amoateng   +6 more
doaj   +1 more source

Delta-mediated cross-frequency coupling organizes oscillatory activity across the rat cortico-basal ganglia network [PDF]

open access: yes, 2013
The brain's ability to integrate different behavioral and cognitive processes relies on its capacity to generate neural oscillations in a cooperative and coordinated manner.
Ivan Cordon   +5 more
core   +1 more source

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