Die Wirkungen von Peroxisomenproliferatoren auf primäre Hepatocyten aus der Regenbogenforelle (Oncorhynchus mykiss) und die permanente Fischzelllinie RTG-2 aus der Gonade der Regenbogenforelle [PDF]
, 2001 Clofibrat dient zur Senkung von Lipiden und Cholesterin im Blut. Es ist ein Peroxisomenproliferator in Ratten und Mäusen und kann Krebs auslösen. Diese Effekte werden in Primaten nicht beobachtet.
Berbner, Thomas
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Anais da Academia Brasileira de Ciências, 2016 Salvia officinalis (Lamiaceae) has been used in south of Brazil as a diary homemade, in food condiment and tea-beverage used for the treatment of several disorders. The objective of this study was to characterize chemical compounds in the hydroalcoholic (
CHARLENE S.C. GARCIA +9 more
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Neuroprotektion und Aktivierung von Neurotrophin-Signaltransduktionswegen durch Hemmung von Protein-Tyrosin-Phosphatasen und durch NO-Donatoren [PDF]
, 2004 Trotz des enormen Fortschrittes der Medizin und neuen Erkenntnissen über die pathologischen Mechanismen des neuronalen Zelltodes steht bislang keine wirkungsvolle, kausale Therapie zur Behandlung neurodegenerativer Erkrankungen zur ...
Gerling, Norbert +1 more
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Ghrelin protects against cell death in myocardial ischaemia: Emerging role of microRNA
Experimental Physiology, Volume 111, Issue 4, Page 1618-1625, 1 April 2026.Abstract Acute myocardial infarction (MI) accelerates cardiomyocyte apoptosis, which underpins ventricular remodelling and dysfunction. The hormone ghrelin mitigates this remodelling, but the mechanisms remain unclear. Specific microRNAs (miRs) are key modulators and reliable biomarkers of early‐stage apoptosis.
Rajesh Katare +2 more
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Kint3-4 promotes apoptosis and inhibition of angiogenesis in solid Ehrlich Tumor
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2012 A proteína Kint3-4 (PKint3-4), codificadora da angiostatina, é reconhecida por sua potencialidade antiangiogênica. O presente estudo teve como objetivo avaliar o efeito da proteína Kint3-4 no crescimento do tumor sólido de Ehrlich.
C Souza +4 more
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Untersuchungen zur Chemo- und Radiosensitivität und deren Auswirkungen auf Zellzyklus, Apoptoseinduktion und Genexpression in neuroendokrinen Pankreastumorzellen [PDF]
, 2005 Die zur Behandlung maligner neuroendokriner gastroenteropankreatischer Tumoren eingesetzten Chemotherapeutika führen bisher zu keiner deutlich verbesserten Überlebenszeit der Patienten.
Robbel, Christian +1 more
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Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity
Advanced Science, Volume 13, Issue 14, 9 March 2026.Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini +24 more
wiley +1 more source
Leucemia mielóide crônica e o sistema Fas-FasL Chronic myeloid leukemia and the Fas-FasL system
Revista Brasileira de Hematologia e Hemoterapia, 2005 Com os avanços terapêuticos que incluem o mesilato de imatinibe, o transplante de medula óssea e a infusão de linfócito do doador, a perspectiva de vida dos portadores de leucemia mielóide crônica (LMC) tem aumentado significativamente e a doença pode ...
Ana Paula F. Bergantini +3 more
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Pathogenesis of Age‐Related Hearing Loss and Therapeutic Strategies
Sensory Neuroscience, Volume 2, Issue 1, March 2026.ABSTRACT Age‐related hearing loss (ARHL) is a degenerative disorder of the auditory system, characterized by bilateral symmetrical sensorineural hearing loss that occurs with aging. As a highly prevalent age‐related condition worldwide, ARHL significantly impairs both the quality of life and mental health of the elderly.
Yu Xiao +6 more
wiley +1 more source
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2003 Noventa e seis pintos de corte foram mantidos em diferentes temperaturas ambientais (calor, 29ºC; neutro, 24ºC; frio, 15ºC) e oito aves de cada grupo de temperatura (tratamento) foram sacrificadas nos dias 1, 7, 14, 21, 28, 35 e 42, e suas bolsas ...
E.B. Guimarães +6 more
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