Results 41 to 50 of about 64,094 (275)
N6-Adenosine Methylation of miRNA-200b-3p Influences Its Functionality and Is a Theranostic Tool
Molecular Therapy: Nucleic Acids, 2020 MicroRNAs (miRNAs or miRs) play crucial roles in biological and pathological processes. Some miRNAs also appear as promising biomarkers and therapeutic tools. However, the epitranscriptomic regulation of miRNAs is not yet fully elucidated in all of their
Joséphine Briand +7 more
doaj
Sensitivierung von Osteosarkomzellen für Strahlen- und Chemotherapie durch das SMAC mimetic LCL161 [PDF]
, 2018 Osteosarkome sind die häufigsten malignen Knochentumoren im Kindes- und Jugendalter. Die Behandlung von Osteosarkomen wurde in den 1970er Jahren durch die Einführung einer intensiven Polychemotherapie revolutioniert, konnte jedoch seitdem kaum verbessert
Erdmann, Marie-Sophie
core +1 more source
O envolvimento de genes e proteínas na regulação da apoptose – Carcinogênese
Revista Brasileira de Cancerologia, 2022 A apoptose é um fator importante em muitos processos biológicos normais, tais como a embriogênese, o desenvolvimento do sistema imune, a maturação e a diferenciação celular. Em situações patológicas, a apoptose parece estar implicada na imunodeficiência,
Ana Bárbara M. Delfino +4 more
doaj +1 more source
The Journal of Cell Biology, 2004 ![][1] Dead cells bind dye nonspecifically. Suicide in a unicellular organism might sound like a lousy idea, but there are several possible justifications. Budding yeast cells that are sickly, mating-incompetent, or stuck in the middle of a colony might do better to go out with ...
openaire +3 more sources
Estresse oxidativo e aumento da apoptose em neutrófilos de cães com azotemia pré-renal
, 2013 O presente trabalho tem como objetivo testar a hipotese de que, a semelhanca do que ocorre na uremia, caes com azotemia pre-renal sofrem estresse oxidativo, o qual esta relacionado com alteracoes do metabolismo oxidativo e apoptose dos neutrofilos.
A. C. Silva +5 more
semanticscholar +1 more source
Endocycling cells do not apoptose in response to DNA rereplication genotoxic stress.
Genes & Development, 2008 Initiation of DNA replication at origins more than once per cell cycle results in rereplication and has been implicated in cancer. Here we use Drosophila to examine the checkpoint responses to rereplication in a developmental context.
Sonam Mehrotra +4 more
semanticscholar +1 more source
Leucemia mielóide crônica e o sistema Fas-FasL Chronic myeloid leukemia and the Fas-FasL system
Revista Brasileira de Hematologia e Hemoterapia, 2005 Com os avanços terapêuticos que incluem o mesilato de imatinibe, o transplante de medula óssea e a infusão de linfócito do doador, a perspectiva de vida dos portadores de leucemia mielóide crônica (LMC) tem aumentado significativamente e a doença pode ...
Ana Paula F. Bergantini +3 more
doaj +1 more source
Das tumortherapeutische Potential optimierter Agonisten der Rezeptoren des Apoptose-induzierenden Liganden TRAIL [PDF]
, 2005 Trotz der Entwicklung neuer Wirkstoffen und verbesserter Therapien ist die Bekämpfung von Tumoren weiterhin eine große Herausforderung. Apo-2L oder „tumor necrosis factor (TNF)-related apoptosis ligand“ (TRAIL), TRAIL, ist ein Mitglied der TNF-Familie ...
Eilers, Martin (Prof. Dr.) +1 more
core +1 more source
Environmental modulators of vascular physiology and inflammation
Experimental Physiology, EarlyView.Abstract Environmental factors play a crucial role in modulating vascular inflammation, contributing significantly to the development of atherosclerosis and cardiovascular disease. This review synthesizes current evidence on how various environmental exposures influence vascular function and inflammation, with a focus on pollutants such as particulate ...
Anusha N. Seneviratne +3 more
wiley +1 more source
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2007 Investigou-se o resultado da isquemia, da congestão e da reperfusão na ocorrência de apoptose. Modelos de obstrução vascular total - artériovenosa e venosa - foram induzidos no jejuno por 2h, seguidos de reperfusão durante 12h.
J.M.G. Abreu +4 more
doaj +1 more source