Results 11 to 20 of about 2,974,203 (387)
Necroptosis, pyroptosis and apoptosis: an intricate game of cell death
Cellular & Molecular Immunology, 2021 Cell death is a fundamental physiological process in all living organisms. Its roles extend from embryonic development, organ maintenance, and aging to the coordination of immune responses and autoimmunity.
D. Bertheloot, E. Latz, B. S. Franklin
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The Oncologist, 1999 Mechanisms in Hematology is a book with an accompanying interactive CD-ROM designed to assemble basic concepts that underlie clinical understanding and progress. It is presented as a concise text with a series of diagrams that distill diffuse information into a compact form.
Esther D. Israels, Lyonel G. Israels and
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Autophagy in Tumor Immunity and Viral-Based Immunotherapeutic Approaches in Cancer
Cells, 2021 Autophagy is a fundamental catabolic process essential for the maintenance of cellular and tissue homeostasis, as well as directly contributing to the control of invading pathogens.
Ali Zahedi-Amiri +4 more
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Inhibitor of apoptosis proteins and apoptosis [PDF]
Acta Biochimica et Biophysica Sinica, 2008 Apoptosis is a physiological cell death process that plays a critical role in development, homeostasis, and immune defense of multicellular animals. Inhibitor of apoptosis proteins (IAPs) constitute a family of proteins that possess between one and three baculovirus IAP repeats.
Yunbo Wei, Tingjun Fan, Miaomiao Yu
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Molecular Oncology, 2023 A better understanding of multiple myeloma (MM) biology has led to the development of novel therapies. However, MM is still an incurable disease and new pharmacological strategies are needed. Dinaciclib, a multiple cyclin‐dependent kinase (CDK) inhibitor,
Manuel Beltrán‐Visiedo +11 more
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Regulated IRE1α-dependent decay (RIDD)-mediated reprograming of lipid metabolism in cancer
Nature Communications, 2022 IRE1α cleaves several mRNAs upon accumulation of misfolded proteins. Here the authors show that active IRE1α cleaves DGAT2 mRNA encoding the rate-limiting enzyme in the synthesis of triacylglycerols, suggesting a role of IRE1α in reprogramming lipid ...
Aitor Almanza +13 more
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Feeder Cells at the Interface of Natural Killer Cell Activation, Expansion and Gene Editing
Frontiers in Immunology, 2022 Genome engineered natural killer (NK) cell therapies are emerging as a promising cancer immunotherapy platform with potential advantages and remaining uncertainties.
Mark Gurney +5 more
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OncoImmunology, 2022 Immunogenic cell death (ICD) has been proposed to be a crucial process for antitumor immunosurveillance. ICD is characterized by the exposure and emission of Damage Associated Molecular Patterns (DAMP), including calreticulin (CRT).
Alfonso Serrano Del Valle +11 more
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Introduction to Apoptosis [PDF]
Diagnostic Molecular Pathology, 1995 Kerr and colleagues (II) coined the term" apoptosis" to designate a particular form of cell death distinct from necrosis. The salient features of apoptosis, which Kerr defined in histopathologic terms, were the breakup of individual cells into smaller, often round or ovoid cytoplasmic fragments containing pyknotic nuclear debris, called" apoptotic ...
Diaz-Cano, Salvador J., R N Salomon
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Skeletal Muscle, 2019 Background Skeletal muscle atrophy is a pathological condition that contributes to morbidity in a variety of conditions including denervation, cachexia, and aging. Muscle atrophy is characterized as decreased muscle fiber cross-sectional area and protein
Neena Lala-Tabbert +7 more
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