Results 31 to 40 of about 1,587,813 (316)

Suspension-Induced Stem Cell Transition: A Non-Transgenic Method to Generate Adult Stem Cells from Mouse and Human Somatic Cells

Cells, 2023
Adult stem cells (ASCs) can be cultured with difficulty from most tissues, often requiring chemical or transgenic modification to achieve adequate quantities. We show here that mouse primary fibroblasts, grown in suspension, change from the elongated and
Behzad Yeganeh, Azadeh Yeganeh, Kyle Malone, Shawn T. Beug, Robert P. Jankov   +4 more
doaj   +1 more source

IAP-IAP complexes required for apoptosis resistance of C. trachomatis-infected cells [PDF]

, 2006
Host cells infected with obligate intracellular bacteria Chlamydia trachomatis are profoundly resistant to diverse apoptotic stimuli. The molecular mechanisms underlying the block in apoptotic signaling of infected cells is not well understood.
Manu Sharma, Nicole Paland, Nikolaus Machuy, Thieck, Oliver, Oswald, Monique, Robert Hurwitz, Oswald, M., Machuy, Nikolaus, Sharma, Manu, Thomas Rudel, Rajalingam, K., Sharma, M., Monique Oswald, Rudel, T., Paland, Nicole, Thieck, O., Rudel, Thomas, Oliver Thieck, Hurwitz, Robert, Krishnaraj Rajalingam, Paland, N., Machuy, N., Rajalingam, Krishnaraj, Hurwitz, R.   +23 more
core   +1 more source

Bim and Bmf synergize to induce apoptosis in Neisseria gonorrhoeae infection [PDF]

, 2009
: Bcl-2 family proteins including the pro-apoptotic BH3-only proteins are central regulators of apoptotic cell death. Here we show by a focused siRNA miniscreen that the synergistic action of the BH3-only proteins Bim and Bmf is required for apoptosis ...
Kepp, Oliver, Yuri Churin, Nikolaus Machuy, Kathleen Gottschalk, Kepp, O., Gottschalk, K., Machuy, Nikolaus, Kroemer, G., Oliver Kepp, Gottschalk, Kathleen, Thomas Rudel, Rajalingam, K., Churin, Yuri, Rudel, T., Churin, Y., Rudel, Thomas, Volker Brinkmann, Krishnaraj Rajalingam, Machuy, N., Brinkmann, Volker, Rajalingam, Krishnaraj, Brinkmann, V., Guido Kroemer, Kroemer, Guido   +23 more
core   +2 more sources

The Proanthocyanidin-Rich Fraction Obtained from Red Rice Germ and Bran Extract Induces HepG2 Hepatocellular Carcinoma Cell Apoptosis

Molecules, 2019
This study aims to determine the anti-carcinogenic effects of the proanthocyanidin-rich fraction (PRFR) obtained from red rice germ and bran extract on HepG2 cells.
Supranee Upanan, Supachai Yodkeeree, Pilaiporn Thippraphan, Wanisa Punfa, Rawiwan Wongpoomchai, Pornngarm Limtrakul (Dejkriengkraikul)   +5 more
doaj   +1 more source

Evolution of apoptosis-like programmed cell death in unicellular protozoan parasites [PDF]

, 2011
Apoptosis-like programmed cell death (PCD) has recently been described in multiple taxa of unicellular protists, including the protozoan parasites Plasmodium, Trypanosoma and Leishmania.
Sarah E Reece, Szymon Kaczanowski, Reece, Sarah E., Kaczanowski Szymon, Kaczanowski, S., Reece, S.E., Reece Sarah E, Mohammed Sajid, Sajid Mohammed, Sajid, M., Reece, Sarah, Sajid, Mohammed, Kaczanowski, Szymon   +12 more
core   +1 more source

Apoptosis and carcinogenesis [PDF]

British Medical Bulletin, 1997
Many tumours are characterised by increased levels of apoptosis. This observation establishes significance for this process in tumour development, but it does little to elucidate the nature of this role, nor does it yield information relevant to the early stages of carcinogenesis.
S K, Lyons, A R, Clarke
openaire   +2 more sources

The meaning of death : evolution and ecology of apoptosis in protozoan parasites [PDF]

, 2011
This work was funded by the Wellcome Trust (SER: WT082234MA; http://www.wellcome.ac.uk/), the NERC (LCP: studentship), the Royal Society of London (AG: University Research Fellowship; http://royalsociety.org/), and Balliol College, University of Oxford ...
Colegrave, Nick, Sarah E Reece, Sarah E. Reece, Pollitt Laura C., Colegrave Nick, Reece, Sarah E., Gardner, A, Pollitt, Laura C., Colegrave, N, Laura C Pollitt, Nick Colegrave, Gardner Andy, Gardner, Andy, Pollitt, LC, Reece, SE, Reece Sarah E., Andy Gardner, Laura C. Pollitt   +17 more
core   +2 more sources

Photoablation at single cell resolution and its application in the Drosophila epidermis and peripheral nervous system

Frontiers in Physiology, 2023
Tissues contain diverse cell populations that, together, make up physiologically functional units. A remarkable example is the animal epidermis, where neuronal and non-neuronal cells intermingle to allow somatosensory perception.
Federica Mangione, Rocco D’Antuono, Nicolas Tapon   +2 more
doaj   +1 more source

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger, Efrat Bar‐Ilan, Victoria Marcu, Evgeny Grishin, Rinat Yacobi, Aviv Barzilai, Hana Golan, Assaf Arie Barg   +7 more
wiley   +1 more source

Investigating the evolution of apoptosis in malaria parasites: the importance of ecology [PDF]

, 2010
Apoptosis is a precisely regulated process of cell death which occurs widely in multicellular organisms and is essential for normal development and immune defences.
Colegrave, Nick, Sarah E Reece, Khan, Shahid M., Reece, Sarah E., Colegrave, N., Pollitt, Laura C., Laura C Pollitt, Nick Colegrave, Reece, S.E., Mohammed Sajid, Pollitt, L.C., Khan, S.M., Sajid, M., Sajid, Mohammed, Shahid M Khan   +14 more
core   +1 more source