Results 211 to 220 of about 2,361,281 (339)

p28GANK knockdown-derived reactive oxygen species induces apoptosis through mitochondrial dysfunction mediated by p38 in hepG2 cells

, 1992
Wang
openalex   +2 more sources

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

Mechanisms of Oncolytic Virus-Induced Multi-Modal Cell Death and Therapeutic Prospects. [PDF]

Int J Mol Sci
Xu J, Liu C, An Y, Sun J, Wang S, Xia Q.
europepmc   +1 more source

Correction of accelerated autoimmune disease by early replacement of the mutated lpr gene with the normal Fas apoptosis gene in the T cells of transgenic MRL-lpr/lpr mice. [PDF]

, 1994
Jian Wu, Tianyu Zhou, J Zhang, Jin He, William C. Gause, J D Mountz   +5 more
openalex   +1 more source

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

FEBS Open Bio, EarlyView.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro, Afshan F. Nawas, Jessica A. Kilgore, Pedro A. S. Nogueira, M.Carmen Lafita‐Navarro, Paul H. Acosta, Roy Garcia, Noelle S. Williams, Maralice Conacci‐Sorrell   +8 more
wiley   +1 more source

Chimeric antigen receptor cells as a tool for localized delivery of TNFα in solid cancer treatment. [PDF]

Hum Vaccin Immunother
Yao Z, Sittplangkoon C.
europepmc   +1 more source

A novel protein domain required for apoptosis. Mutational analysis of human Fas antigen

, 1993
Naoto Itoh, Shigekazu Nagata
openalex   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Author Correction: SIRT2-mediated deacetylation and deubiquitination of C/EBPβ prevents ethanol-induced liver injury

Cell Discovery, 2023
Yingting Zhang, Xidai Long, Xin Ruan, Qian Wei, Lin Zhang, Lulu Wo, Dongdong Huang, Longshuai Lin, Difei Wang, Li Xia, Qinghua Zhao, Junling Liu, Qian Zhao, Ming He   +13 more
doaj   +1 more source

Programmed Cell Death in Diabetic Kidney Disease: Mechanisms and Therapeutic Targeting. [PDF]

J Inflamm Res
Tang S, Sun Y, Sun W, Kang X, Zhao X, Jiang L, Gao Q, An X, Ji H, Lian F.   +9 more
europepmc   +1 more source