Results 241 to 250 of about 2,974,203 (387)

Peroxiredoxin 2 regulates DAF-16/FOXO mediated mitochondrial remodelling in response to exercise that is disrupted in ageing

Molecular Metabolism
Objectives: A decline in mitochondrial function and increased susceptibility to oxidative stress is a hallmark of ageing. Exercise endogenously generates reactive oxygen species (ROS) in skeletal muscle and promotes mitochondrial remodelling resulting in
Qin Xia, Penglin Li, José C. Casas-Martinez, Antonio Miranda-Vizuete, Emma McDermott, Peter Dockery, Katarzyna Goljanek-Whysall, Brian McDonagh   +7 more
doaj  

Differentiation of HL-60 cells into primed neutrophils for the evaluation of antiapoptotic effects of poorly soluble nanoparticles. [PDF]

PLoS One
Hornstein T, Unfried K.
europepmc   +1 more source

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source

Apoptosis: A Key Process That <i>Trypanosoma cruzi</i> Modulates as a Strategy to Perpetuate Infection. [PDF]

J Parasitol Res
Coria-Paredes DM, Wilkins-Rodríguez AA, Gutiérrez-Kobeh L.   +2 more
europepmc   +1 more source

Mitochondrial DNA is not fragmented during apoptosis.

, 1992
Marta Murgia, Paola Pizzo, Dorianna Sandonà, Paola Zanovello, Rosario Rizzuto, Francesco Di Virgilio   +5 more
openalex   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

Structural mechanism of VWF D’D3 dimer formation

Cell Discovery, 2022
Zimei Shu, Jianwei Zeng, Li Xia, Haiyan Cai, Aiwu Zhou   +4 more
doaj   +1 more source

Unlocking the mitochondrial functional code: unraveling the pathogenesis of ovarian cancer and innovative targets to inhibit malignant behavior. [PDF]

J Transl Med
Li CY, Ding DN, Guo Y, Fu Y, Shen Y, Fu JM, Zhang CX, Han FJ.   +7 more
europepmc   +1 more source

Wild-type p53 is required for apoptosis induced by growth factor deprivation in factor-dependent leukaemic cells

, 1994
Y-M Zhu, D. A. Bradbury, N. H. Russell
openalex   +2 more sources

Evidence that BCL-2 represses apoptosis by regulating endoplasmic reticulum-associated Ca2+ fluxes. [PDF]

, 1994
Mildred Lam, George Dubyak, Liang Chen, Gabriel Núñez, Roger L. Miesfeld, C W Distelhorst   +5 more
openalex   +1 more source