Results 101 to 110 of about 69,801 (269)

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić   +7 more
wiley   +1 more source

An open‐label, single‐arm, dose‐escalating concentration–QT study to investigate the cardiac effects and safety of paroxetine in healthy adults

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Paroxetine is a selective serotonin reuptake inhibitor (SSRI), approved for treatment of major depressive disorder and anxiety disorders. Some SSRIs are known to prolong the QT interval; however, clinical evidence to establish a lack of association between paroxetine and corrected QT interval (QTc) prolongation is limited. Therefore, this
Sven C. van Dijkman   +6 more
wiley   +1 more source

Ghrelin and its role in health and disease

open access: yesТерапевтический архив, 2013
The paper provides a review of the present-day literature on the role of the hormone ghrelin discovered in 1999.
I V Tereshchenko, P E Kaiushev
doaj  

A Serotonin-Dependent Mechanism Explains the Leptin Regulation of Bone Mass, Appetite, and Energy Expenditure [PDF]

open access: bronze, 2009
Vijay K. Yadav   +14 more
openalex   +1 more source

Cannabinoids and drug–drug pharmacokinetic interactions: Deciphering the risks

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
The relationship between cannabinoids and mental health has become a major focus of scientific inquiry and public discourse. Cannabinoids are diverse chemical compounds from the Cannabis species that have been explored for their therapeutic applications in treating chronic pain, psychiatric and neurological conditions, such as depression, schizophrenia,
Paraskevi Papakyriakopoulou   +2 more
wiley   +1 more source

Effects of voluntary wheel running on appetite-regulating peptides and neuroinflammation in the hypothalamus of ovariectomized middle-aged mice

open access: yesFrontiers in Molecular Neuroscience
The postmenopausal period is associated with an increased tendency to gain weight. This may be due to disturbances in appetite regulation, mainly in the hypothalamus and nutritional behaviors, as well as persistent neuroinflammation resulting from ...
Mateusz Grabowski   +7 more
doaj   +1 more source

What characterises well‐connected schools? Exploring centrality in inter‐organisational school networks

open access: yesBritish Educational Research Journal, EarlyView.
Abstract Within the educational literature, inter‐organisational school networks are commonly considered instruments for administration, management, and school improvement, but are rarely scrutinised as objects of study themselves. Conversely, in organisational studies, this perspective is given more prominence.
Ignacio Wyman, Paul Wilfred Armstrong
wiley   +1 more source

Intergenerational transmission of appetite self-regulation [PDF]

open access: green, 2021
Nicole R. Giuliani   +2 more
openalex   +1 more source

A pipeline crisis or a sustainability crisis? Local and national succession planning for headteachers in England

open access: yesBritish Educational Research Journal, EarlyView.
Abstract Recruiting and retaining school leaders is a challenge in many systems worldwide. Previous research has identified three distinct ways in which succession planning can be conceptualised and approached: a ‘pipeline’ approach seeks to match supply and demand for the posts that need filling; a ‘pool’ strategy involves proactively identifying and ...
Toby Greany   +3 more
wiley   +1 more source

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