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Annals of the New York Academy of Sciences, 2018
Over the past few years, scientific interest in the gut–brain axis (i.e., the bidirectional communication system between the gastrointestinal tract and the brain) has exploded, mostly due to the identification of the gut microbiota as a novel key player ...
N. Weltens +3 more
semanticscholar +1 more source
Over the past few years, scientific interest in the gut–brain axis (i.e., the bidirectional communication system between the gastrointestinal tract and the brain) has exploded, mostly due to the identification of the gut microbiota as a novel key player ...
N. Weltens +3 more
semanticscholar +1 more source
Appetite Regulation: An Overview
Thyroid, 2007Obesity is a major public health problem associated with morbidity and mortality and continues to increase worldwide. This review focuses on the regions of the brain that are important in appetite regulation and the circulating factors implicated in the control of food intake.
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Gut peptides and the regulation of appetite
Obesity Reviews, 2006SummaryThere is a growing worldwide epidemic of obesity. Obese people have a higher incidence of type 2 diabetes and cardiovascular disease, and hence present increasing social, financial and health burdens. Weight loss is always difficult to achieve through lifestyle changes alone, and currently licensed anti‐obesity drug treatments, such as orlistat ...
Jonathan Pinkney +2 more
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Robust modeling of appetite regulation
Journal of Theoretical Biology, 2011The interaction between appetite activation and the energy content of the brain and the body is mathematically modeled. General influence functions with saturation are used to describe the interaction. The resulting class of models is investigated with respect to the circadian periodicity of human food intake. We show that very weak and physiologically
Kerstin M. Oltmanns +5 more
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Appetite regulation and energy balance
Acta Paediatrica, 2005AbstractThe decision to begin eating or to stop eating is a complex process. Hunger is primarily driven by hunger signals, like ghrelin and neuropeptide Y, originating from the gastrointestinal tract and from the hypothalamus. The hunger signals stimulate the seeking of food and the eating, being activating for the body and mind.
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Appetite Regulation by Gut Peptides
Annual Review of Nutrition, 1990A number of gastrointestinal hormones that are released from the gut in response to intraluminal food stuffs have been shown to play a role in producing satiety. Some of these hormones apparently activate ascending vagal fibers that send messages to the nucleus tractus solitarius, and perhaps from there messages are sent to the paraventricular nucleus ...
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Hypothalamic neuropeptides and the regulation of appetite
Neuropharmacology, 2012Neuropeptides released by hypothalamic neurons play a major role in the regulation of feeding, acting both within the hypothalamus, and at other appetite regulating centres throughout the brain. Where classical neurotransmitters signal only within synapses, neuropeptides diffuse over greater distances affecting both nearby and distant neurons ...
Stephen R. Bloom, Jennifer Parker
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Regulation of Appetite and Body Weight
Hospital Practice, 1997Short-term variations in caloric intake and energy expenditure-including attempts by obese patients to lose weight-tend to be modified by the body's long-term weight regulatory system. Hormones such as leptin and insulin participate in this system, which links changes in body fat content to appropriate compensatory responses in the hypothalamus ...
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Appetite and the regulation of body composition
The FASEB Journal, 1994Stability of body composition requires that energy intake equals energy expenditure when integrated over prolonged periods. As recent human studies have failed to demonstrate active changes in energy expenditure with changes in body composition, it is likely that energy intake is continually adjusted to preserve a constant total adipose tissue mass. If
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