Results 81 to 90 of about 103,741 (231)
Effect of human myoblasts on tenogenic progression in 2D and 3D culture models
Journal of Anatomy, Volume 248, Issue 4, Page 653-663, April 2026.We investigated whether factors released from muscle derived myogenic cells enhance tenogenic progressions of human tendon derived cells using two‐dimensional (2D) culture model and a three‐dimensional (3D)‐engineered tendon construct culture model.
Yoshifumi Tsuchiya +3 more
wiley +1 more source
Fibrinolysis protease receptors promote activation of astrocytes to express pro-inflammatory cytokines. [PDF]
, 2019 BACKGROUND:Astrocytes contribute to the crosstalk that generates chronic neuro-inflammation in neurological diseases; however, compared with microglia, astrocytes respond to a more limited continuum of innate immune system stimulants.
Azmoon, Pardis +8 more
core +1 more source
The FASEB Journal, Volume 40, Issue 6, 31 March 2026.Heat shock induces Arc/Arg3.1 Cys34‐Cys159 disulfide crosslinking, promoting oligomerization and Hsp70‐CHIP‐dependent ubiquitination followed by proteasomal degradation during recovery. Disrupting disulfide formation (C159A) impairs CHIP‐mediated ubiquitination and stabilizes Arc/Arg3.1, whereas HSF1 loss limits inducible Hsp70 and leads to Arc ...
Dami So +7 more
wiley +1 more source
Общая реаниматология, 2007 Objective: to comparatively evaluate the efficiency and safety of trasylol and aprotex used in the treatment of the fibrinolytic type of disseminated intravascular coagulation (DIC) syndrome after long abdominal operations.Materials and methods.
S. V. Sinkov +3 more
doaj +1 more source
A lymphoma plasma membrane-associated protein with ankyrin-like properties. [PDF]
, 1986 In this study we have used several complementary techniques to isolate and characterize a 72-kD polypeptide that is tightly associated with a major mouse T-lymphoma membrane glycoprotein, gp 85 (a wheat germ agglutinin-binding protein), in a 16 S complex.
Balazovich, K +3 more
core
A Molecular Basis for Stabilization of the von Hippel-Lindau (VHL) Tumor Suppressor Protein by Components of the VHL Ubiquitin Ligase [PDF]
, 2002 The multiprotein von Hippel-Lindau (VHL) tumor suppressor (CBCVHL, Cul2-Elongin BC-VHL) and SCF (Skp1-Cul1/Cdc53-F-box protein) complexes are members of structurally related families of E3 ubiquitin ligases that use a heterodimeric module composed of a ...
Brower, Christopher S. +3 more
core +2 more sources
The FASEB Journal, Volume 40, Issue 6, 31 March 2026.Human primary myoblasts were subjected to 2% or 10% static mechanical loading for 24 h, with unloaded cells as controls. Conditioned media were collected and applied, together with normal medium, to a 3D tendon fibrin gel model. Secretome from loaded myoblasts, particularly 2% loading, enhanced tenocyte proliferation, scleraxis (SCX) expression, and ...
Junhong Li +4 more
wiley +1 more source
The FASEB Journal, Volume 40, Issue 6, 31 March 2026.CADASIL is the major cause of early‐onset stroke and cognitive dysfunction, including dementia. It is caused by mutations in the NOTCH3 receptor that result in the formation of protein aggregates in the small vessel walls of the brain. We demonstrated that NOTCH3 CADASIL variant receptor aggregation is strictly dependent on interactions with NOTCH3 ...
Haijiang Wang +9 more
wiley +1 more source
The FASEB Journal, Volume 40, Issue 5, 15 March 2026.In SH‐SY5Y cells, Methylglyoxal (MGO) reduces the intracellular dopamine content, up‐regulating the expression of proteins that modulate dopamine amount (MAO‐B, COMT, and α‐Syn). The MGO‐induced increase of COMT and α‐Syn expression is mediated by the reduction of miR‐214 and miR‐190a levels.
Alessandra Croce +9 more
wiley +1 more source