A Simple Programmable Cas12a/crRNA Induced Walking System for Sensitive Methicillin-Resistant <i>Staphylococcus aureus</i> Detection via Integrated <i>cis</i>- and <i>trans</i>-Cleavage Activity. [PDF]
Xiao B, Zhang J.
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Optimized Aptamer-Conjugated Gold Nanoparticles for Specific Detection of GII.4 Human Norovirus in Feces. [PDF]
Cheng C +10 more
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Computationally-designed aptamers targeting RAD51-BRCA2 interaction impair homologous recombination and induce synthetic lethality. [PDF]
Milordini G +14 more
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Expanded genetic alphabet increases structural and chemical diversity of six-letter DNA for high-affinity protein-targeting aptamers. [PDF]
Sawada K +12 more
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DNA aptamer Apt<sub>ERA</sub> 2 targets ERA from Staphylococcus aureus and limits GTP hydrolysis. [PDF]
PeƱaranda K +6 more
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RNA aptamers as tools for the purification and analysis of in vivo assembled ribonucleoproteins. [PDF]
Rocca DG, Kothe U.
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Recent Advances in the Detection of Aflatoxin M1 in Milk and Dairy Products. [PDF]
Maurelli AM +4 more
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Theranostic Bionanomaterials, 2019Polymeric aptamers, or chemical antibodies, consisting of oligonucleotides are regarded as upgraded polypeptidic antibodies. Aptamers are often sorted through systematic evolution of ligands by exponential enrichment.
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Artificial Nucleotide-containing Aptamers Used in Tumor Therapy
Chemical Research in Chinese Universities, 2019The high pharmaceutical cost and multi-drug resistance in tumor therapeutic agents hinder the further application of chemotherapy in tumor therapy. Artificial modified nucleic acid aptamers have the advantages of high binding affinity, programmability, and easy synthesis.
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HPLC purification of RNA aptamers up to 59 nucleotides with single-nucleotide resolution.
Methods in molecular biology, 2015An RNA sample is usually heterogeneous. RNA heterogeneity refers to difference in length or size (i.e., number of nucleotides [nt]), sequence, or alternative but coexisting conformations. Separation and purification of RNA is generally required for investigating the structure and function of RNA, such as RNA catalysis and RNA structure determination by
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