Results 171 to 180 of about 29,754 (236)

Enhancing the Sensitivity of Colorimetric Aptasensor Through Cd2+‐Thymine Interactions in ssDNA Loops for Food Contaminant Detection

Food Safety and Health, EarlyView.
This picture illustrates a novel aptamer‐based colorimetric assay, which demonstrates that high sensitivity, selectivity, and reliability for the rapid detection of cadmium ions (Cd2+) in water. Molecular dynamics (MD) simulations have revealed that the complexes are more stable, with Cd2+ binding more tightly to the thymine (T) within the aptamer loop.
Xuyan Li, Xinyu Ni, Yue Li, Xusheng Li, Dongbao Cai, Jianxia Sun, Chao Wang, Weibin Bai   +7 more
wiley   +1 more source

Sequence optimization of a DNA aptamer inhibiting COVID-19 infection guided by analysis of secondary structure distribution. [PDF]

Comput Struct Biotechnol J
Muniz MI, Carzaniga T, Nava G, Casiraghi L, Giana D, Rocca S, Pedretti A, Dellavedova J, Ciana P, Bellini T, Buscaglia M.   +10 more
europepmc   +1 more source

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

iNew Medicine, EarlyView.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen, Ru Ya, Ziling Zhang, Siyue Dong, Seol Hee Park, Wonhyo Seo, Yong He   +6 more
wiley   +1 more source

RaptScore: a large language model-based algorithm for versatile aptamer evaluation. [PDF]

Nucleic Acids Res
Kimura-Yamazaki A, Adachi T, Nakamura S, Nakamura Y, Hamada M.   +4 more
europepmc   +1 more source

Molecular crosstalk via exosomes in lung cancer progression

Interdisciplinary Medicine, EarlyView.
“Molecular and theranostics roles of exosomes in Lung Cancer.” Abstract Exosomes play a critical role in lung cancer metastasis, facilitating tumor progression through intercellular communication between cancer cells and the tumor microenvironment. These nanosized extracellular vesicles carry bioactive molecules such as proteins, nucleic acids, and ...
Rajib Dhar, Vinoth Kumarasamy, Brian G. Oliver, Vetriselvan Subramaniyan   +3 more
wiley   +1 more source

Affinity Maturation of a Fentanyl Aptamer by Motif-SELEX. [PDF]

JACS Au
Alkhamis O, Canoura J, Castro G, Byrd C, Bryant A, Yu H, Xiao Y.   +6 more
europepmc   +1 more source

A personal 360° view of applications of ‘biomimetic’ molecular recognition

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract Molecular recognition between biological molecules has formed the basis for innumerable applications in biotechnology for the last seven decades or so. Techniques such as affinity chromatography, solid‐phase and aqueous two‐phase extraction, affinity precipitation, biomimetic catalytic systems, biosensors and molecular imprinting all exploit ...
Christopher R Lowe
wiley   +1 more source

Aptamer-liposome targeted nanotherapeutics for cancer therapy: Bibliometric analysis, recent developments and future perspectives. [PDF]

Mater Today Bio
Gao Z, Du S, Song J, Gao Y, Peng X, Lin X, E S, Zhao Y, Zhang S.   +8 more
europepmc   +1 more source

Recent Advances in Photonic Bound States in the Continuum: From Fundamentals to Engineering and Implementation

Laser &Photonics Reviews, EarlyView.
This review summarizes recent progress in meta‐photonics with a focus on bound states in the continuum (BICs) as a powerful platform for light confinement and control. It covers fundamental concepts, design strategies across optical regimes, symmetry breaking for practical quasi‐BICs, tunable and AI‐assisted BIC devices, and emerging applications in ...
Hafiz Saad Khaliq, Hak‐Rin Kim
wiley   +1 more source